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Structures called primary cilia - which act like TV antennas for cells to detect signals - are present in fewer numbers in mice born with Fragile X syndrome, according to researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio). Study results were published July 30 in the journal Stem Cell Reports.
A new study finds that healthcare workers in the United States are struggling with a suite of mental-health challenges during the COVID-19 pandemic. The study reports that healthcare workers are at greater risk than the general public of experiencing health problems such as depression.
One striking finding is that, on average, healthcare professionals reported enough symptoms of depression to be diagnosed with clinical depression.
LOS ANGELES -- Modifying 12 risk factors over a lifetime could delay or prevent 40% of dementia cases, according to an updated report by the Lancet Commission on dementia prevention, intervention and care presented at the Alzheimer's Association International Conference (AAIC 2020).
Philadelphia, July 30, 2020 - In a report in the Journal of Molecular Diagnostics, published by Elsevier, researchers at Augusta University and PerkinElmer Genomics describe a cheaper, rapid, and accurate pooling strategy for the RT-PCR-based detection of SARS-CoV-2 in clinical samples. This assay has a significant impact on large-scale population screening in the wake of the current COVID-19 pandemic.
More than 200 genes with novel and known roles in glioblastoma - the most aggressive type of brain cancer - offer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke's Hospital and their collaborators engineered a new mouse model to show for the first time how a mutation in the well-known cancer gene, EGFR initiates glioblastoma, and works with a selection from more than 200 other genes to drive the cancer.
A new technique that can spot a potential preterm birth in asymptomatic high-risk women, with up to 73% accuracy months before delivery, has been developed by scientists at the University of Warwick.
Utilising cutting-edge volatile organic compound analysis technology, designed to characterise airborne chemicals, the scientists 'trained' the device using machine-learning techniques to identify the chemical vapour patterns from preterm birth using vaginal swabs taken during routine examinations.
A study led by Charité - Universitätsmedizin Berlin and the Max Planck Institute for Molecular Genetics (MPIMG) shows that some healthy individuals possess immune cells capable of recognizing the novel coronavirus, SARS-CoV-2. The reason for this might be found in prior infections with 'common cold' coronaviruses. Whether or not this cross-reactivity has a protective effect on the clinical course in individuals infected with SARS-CoV-2 will now be addressed by the 'Charité Corona Cross' study.
CAMBRIDGE, MA -- Yellow fever, a hemorrhagic disease that is common in South America and sub-Saharan Africa, infects about 200,000 people per year and causes an estimated 30,000 deaths. While there is a vaccine for yellow fever, it can't be given to some people because of the risk of side effects, and there are no approved treatments for the disease.
East Hanover, NJ. July 29, 2020. Researchers in regenerative rehabilitation conducted a pilot study of a new approach to the treatment of treatment-resistant shoulder pain in wheelchair users with spinal cord injury (SCI) and rotator cuff disease. Results were encouraging in the study of six participants who received a combination of a single injection of platelet-rich plasma (PRP) into the supraspinatus tendon and a home-based exercise program of stretching and strengthening.
Hamilton, ON (July 27, 2020) - As provinces across Canada are deciding how to restart schools during the pandemic, a research review has found children are not a major source of transmission of COVID-19.
A second review has found strain on families, particularly women with children.
PHILADELPHIA -- Black and Hispanic pregnant women in Philadelphia are five times as likely as white and Asian women to have been exposed to the novel coronavirus, according to a new study led by Scott Hensley, PhD, an associate professor of Microbiology in the Perelman School of Medicine at the University of Pennsylvania, and Karen Marie Puopolo, MD, PhD, an associate professor of Pediatrics and neonatologist at the Children's Hospital of Philadelphia. The study was published today in Science Immunology.
A group of researchers from Brazil, Denmark, Italy and Spain analyzed 884 samples of fungi of the genus Candida collected from 16 hospitals and found a significant number of clusters in more than one hospital. Clusters are groups of fungal isolates with identical DNA sequences. The discovery may point to the presence of more virulent and drug-resistant varieties.
With communities throughout the United States combating surges in COVID-19 cases and hospitalizations, researchers at The University of Texas at Austin and Northwestern University have created a framework that helps policymakers determine which data to track and when to take action to protect their communities. The model specifies a series of trigger points to help local entities know when to tighten social distancing measures to prevent hospitals from being overrun by virus patients.
Wealthier communities went from being the most mobile before the COVID-19 pandemic to the least mobile, while poorer areas have gone from the least mobile to the most mobile, according to a study by the University of California, Davis.
CHICAGO, July 30, 2020 -- Risk factors for Alzheimer's dementia may be apparent as early as our teens and 20s, according to new research reported at the Alzheimer's Association International Conference® (AAIC®) 2020.