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Philadelphia, August 24, 2020 - Autism is a neurodevelopmental condition that researchers are now tracing back to prenatal development, even though the disorder is not diagnosed until at least 18 months of age. A new study now shows in human brain cells that the atypical development starts at the very earliest stages of brain organization, at the level of individual brain cells.
What The Study Did: COVID-19 among incarcerated individuals and staff in Massachusetts jails and prisons is described in this observational study, which assesses the association of COVID-19 case rates with decarceration and testing rates.
Authors: Monik C. Jiménez, Sc.D., S.M., F.A.H.A., of Brigham and Women's Hospital and Harvard Medical School in Boston, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
What The Study Did: This open-label randomized trial compares the effect of remdesivir (5 or 10 days) compared with standard care on clinical status 11 days after treatment initiation among patients with confirmed SARS-CoV-2 infection hospitalized with moderate pneumonia.
Authors: Diana M. Brainard, M.D., of Gilead Sciences in Foster City, California, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Physicists at the University of Göttingen, together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique that enables high resolution and three-dimensional representation of damaged lung tissue following severe Covid-19. Using a special X-ray microscopy technique, they were able to image changes caused by the coronavirus in the structure of alveoli (the tiny air sacs in the lung) and the vasculature. The results of the study were published in the research journal eLife.
After the first fragility fracture, there is a high risk of subsequent fractures, with the risk highest in the following two years. Despite the enormous human and cost burden of secondary fractures, bone health experts warn that too little is being done to systematically identify and treat high risk patients who are in danger of sustaining such fractures, including highly debilitating and life-threatening hip fractures.
Publication: Journal of General Internal Medicine
Authors: Girish Nadkarni, MD, Co-Chair; Anuradha Lala, MD, Member; Benjamin Glicksberg, PhD, Member; and other coauthors of the Mount Sinai COVID Informatics Center at the Icahn School of Medicine at Mount Sinai.
Bottom Line: This study describes characteristics of patients with COVID-19 who returned to the ER or required readmission to the hospital within 14 days of being discharged. Understanding what conditions impact these patient outcomes can help improve care during the hospital stay and after discharge.
Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects. The drug, which was tested in non-human primates, could eventually replace or supplement components of combination drug "cocktail" therapies currently used to prevent or treat the virus.
The word 'synbiotic' appears on a growing number of food and supplement products, with synbiotic ingredients showing promise for modulating the community of microbes living in the human gut, while providing a health benefit. Synbiotics are generally understood to be a combination of a probiotic and a prebiotic--but experts have deemed this description too limiting for innovation in this field and too ambiguous to allow for a clear understanding of synbiotic health benefits.
Toronto -- Taking advantage of a cancer cell's altered metabolism that drives its runaway growth, Princess Margaret researchers are zeroing in on these molecular changes to help them develop more precise drug targets for one of the most deadly breast cancers.
State handgun purchaser licensing laws--which go beyond federal background checks by requiring a prospective buyer to apply for a license or permit from state or local law enforcement--appear to be highly effective at reducing firearm homicide and suicide rates, according to a new analysis of gun laws in four states from researchers at the Johns Hopkins Bloomberg School of Public Health.
Large forces of trained community health workers and standardised healthcare systems could reduce the number of maternal, newborn and foetal deaths, a study has recommended.
Meta-analysis of three studies, published today in the Lancet, examines the outcomes of 70,000 women in Mozambique, Pakistan and India between 2014-7.
While there is broad support in the United States for pro-vaccination policies, as many as 20% of Americans hold negative views about vaccination. Such misinformed vaccine beliefs are by far the strongest driver of opposition to pro-vaccination public policies - more than political partisanship, education, religiosity or other sociodemographic factors, according to new research from the Annenberg Public Policy Center (APPC) of the University of Pennsylvania.
Philadelphia, August 20, 2020 - In a new study, investigators found that ideal cardiovascular health, which is indicative of a healthy lifestyle, was associated with lower odds for ocular diseases especially diabetic retinopathy. These findings appearing in the American Journal of Medicine, published by Elsevier, suggest that interventions to prevent cardiovascular diseases may also hold promise in preventing ocular diseases.
TUSCALOOSA, Ala. - The prevalence of morbid obesity in a population is associated with negative outcomes from COVID-19, according to an analysis by researchers at The University of Alabama of morbid obesity data and reported COVID-19 deaths in the United States.
CHICAGO--- Deaths due to heart failure and hypertensive heart disease are increasing in the U.S. --particularly in Black women and men -- despite medical and surgical advances in heart disease management, reports a new Northwestern Medicine study.