An image of the HDAC enzyme is available here: https://www.dropbox.com/sh/tafbpgai7ufo1hk/AAA3a1vCIEApA3srynHXnKfta?dl=0
New knowledge about the mechanism of specific protein complexes in the body could help in the development of better drugs for the treatment of diseases such as cancer and Alzheimer's, according to research led by the University of Leicester.
A new study suggests that charter school students are more likely to do well at college and earn significantly more than their counterparts at other schools.
In a sample of young people with type I diabetes, those who actively helped care for family pets were 2.5 times more likely to have well-controlled blood sugar levels, according to a study published April 22, 2016 in the open-access journal PLOS ONE by Louise Maranda from University of Massachusetts Medical School, USA, and colleagues.
The offspring of a brooding sea anemone transition from using egg yolks to pre-natal, then post-natal, parental feeding during their development, according to a study published April 22, 2016 in the open-access journal PLOS ONE by Annie Mercier from Memorial University, Canada, and colleagues.
Researchers from the University of Florida and Union College in Lincoln, NE wondered whether bed bugs preferred certain colors for their hiding places, so they did some testing in the lab. The tests consisted of using small tent-like harborages that were made from colored cardstock and placed in Petri dishes. A bed bug was then placed in the middle of the Petri dish and given ten minutes to choose one of the colored harborages.
PASADENA, Calif., April 25, 2016 -- A new Kaiser Permanente study, published in Pediatric Obesity, found that pre-pregnancy obesity and excessive weight gain during pregnancy was associated with an increased risk of the child becoming overweight at age 2. The study also found breastfeeding for at least six months helped reduce the likelihood of a child being overweight at age 2.
NEW YORK, NY (April 25, 2016) -- A study conducted by researchers at Columbia University Medical Center (CUMC) found that older adults who used a hearing aid performed significantly better on cognitive tests than those who did not use a hearing aid, despite having poorer hearing. The study was published online in the American Journal of Geriatric Psychiatry.
The researchers also found that cognitive function was directly related to hearing ability in participants who did not use a hearing aid.
Psoriasis is a long-lasting autoimmune disease that is characterized by patches of abnormal and inflamed skin. It is generally thought to have a genetic origin, which can be further triggered by environmental factors. People with specific mutations in the CARD14 gene have a high probability of developing psoriasis. A VIB/UGent research team now reveals the molecular signaling mechanism by which mutations in CARD14 lead to increased inflammation in patients with psoriasis. The results are published in the prestigious journal EMBO Reports.
The crucibles that bore out early building blocks of life may have been, in many cases, modest puddles.
Now, researchers working with that hypothesis have achieved a significant advancement toward understanding an evolutionary mystery -- how components of RNA and DNA formed from chemicals present on early Earth before life existed.
In surprisingly simple laboratory reactions in water, under everyday conditions, they have produced what could be good candidates for missing links on the pathway to the code of life.
Large animals play a key role in mitigating climate change in tropical forests across the world by spreading the seeds of large trees that have a high capacity to store carbon, new research co-led by the University of Leeds has said.
The research, published in the journal Nature Communications, sheds important new light on the role seed dispersal by animals plays in mitigating climate change, and how this role can vary in tropical forests across the world.
WASHINGTON -- Seven top international tobacco control experts are prompting regulators at the U.S. Food and Drug Administration (FDA) to have a broad "open-minded" perspective when it comes to regulating vaporized nicotine products, especially e-cigarettes.
Writing in the journal Addiction, published online April 25, the researchers synthesize much of the evidence published to date on e-cigarettes, and suggest that use of these products can lead to reduced cigarette smoking overall with a potential reduction in deaths from cigarette smoking.
(COLUMBUS, Ohio) - A new study conducted by the Center for Injury Research and Policy of the Research Institute at Nationwide Children's Hospital and the Central Ohio Poison Center found that exposure to laundry detergent packets is more dangerous to young children than exposure to other types of laundry and dishwasher detergent.
A "Mediterranean" diet, high in fruit, vegetables, fish and unrefined foods, is linked to a lower risk of heart attack and stroke in people who already have heart disease, according to a study of over 15,000 people in 39 countries around the world. The research also showed that eating greater amounts of healthy food was more important for these people than avoiding unhealthy foods, such as refined grains, sweets, desserts, sugared drinks and deep-fried food - a "Western" diet.
The smoking cessation medications varenicline and bupropion do not appear to increase the incidence of serious neuropsychiatric side effects compared to placebo, according to a study published in The Lancet today.
Compared to the nicotine patch and a placebo, the smoking cessation aids varenicline (marketed as Chantix in the U.S.) and bupropion (Zyban) do not show a significant increase in neuropsychiatric adverse events, reports an international team of researchers in a study published online April 22 in the journal The Lancet.