Body

A study led by researchers at Georgia State University provides new insights into the molecular basis of human diseases resulting from mutations in the calcium-sensing receptor (CaSR), a protein found in cell membranes.

Their findings, published Friday (May 27) in the journal Science Advances, may assist in the development of novel receptor-based therapeutics for mutations that lead to certain types of hypocalcemia and neonatal hyperparathyroidism, in addition to Alzheimer's disease and some cancers.

LOUISVILLE, Ky. - The mouth is one of the "dirtiest" parts of the body, home to millions of germs. But puffing cigarettes can increase the likelihood that certain bacteria like Porphyromonas gingivalis will not only set up camp but will build a fortified city in the mouth and fight against the immune system.

Montreal, May 31, 20016 -- As the summer heats up, so do cities. That's true not just for hot places like Los Angeles and Phoenix, but also for cooler capitals like Ottawa and Reykjavik.

Regardless of latitude, urban temperatures are typically several degrees higher than those of nearby suburban and rural areas. The resulting "heat islands" mean increased discomfort, higher air-conditioning bills and denser smog.

A protein designed by researchers at Georgia State University can effectively target a cell surface receptor linked to a number of diseases, showing potential as a therapeutic treatment for an array of illnesses, including cancer, according to the research team.

WASHINGTON, D.C., May 31, 2016 -- When the script of Lawrence of Arabia called for wrecking a train, director David Lean found it easiest to go ahead and wreck a train, orchestrating and filming it with expert precision. Similarly, while it's possible to study explosives, sans explosives, new techniques involving high-speed, high-fidelity imaging with optical filtering and signal processing techniques have recently made setting off explosives and capturing the data in real-time a reasonable alternative to developing a new simulation.

LOS ALAMOS, N.M., May 31, 2016-- New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases.

A new study by Jonathan R. Clark, assistant professor of management at The University of Texas at San Antonio (UTSA), states that the language of leaders has a profound effect on the performance of their employees. Clark's top-tier research, published in Organizational Dynamics, shows that how a company presents its vision and values is deeply entwined with its overall success.

ATLANTA--A protein designed by researchers at Georgia State University can effectively target a cell surface receptor linked to a number of diseases, showing potential as a therapeutic treatment for an array of illnesses, including cancer, according to the research team.

May 31, 2016 - Many patients undergoing hip or knee replacement are still taking prescription opioid pain medications up to six months after surgery, reports a study in PAIN®, the official publication of the International Association for the Study of Pain® (IASP). The journal is published by Wolters Kluwer.

RIVERSIDE, Calif.

Mantis shrimp are available in the lab and can be photographed or videoed.

A video that media are free to use is here: https://www.youtube.com/watch?v=_8K3bx42jVM

-- The next generation of airplanes, body armor and football helmets crawled out from under a rock--literally.

It's no secret that over time, elevated levels of blood glucose (hyperglycemia) can induce the death of the pancreatic beta cells. The death of these cells, which are responsible for the production of insulin, underlies much of the pathology of diabetes.

New research presented at Euroanaesthesia 2016 (London 27-30 May) shows that patients undergoing breast cancer surgery need less painkilling medication post-surgery if they have anaesthesia that is free of opioid drugs. The study is by Dr Sarah Saxena, Jules Bordet Institute, Brussels, Belgium, and colleagues,

Among the many important processes that happen during a woman's last few weeks of pregnancy is the transfer of calcium to the growing foetus to boost bone development. But what happens if this transfer is interrupted when a baby is born prematurely?

The answer, it seems, is lower peak bone mass as an adult, compared to adults who were born full term. Adults who were born full term but were small for their gestational age also had lower bone mass. These findings are important since peak bone mass is a major determinant of future osteoporosis.

1. Investment in 90-90-90 initiative would yield "extraordinary returns" in the fight against HIV in South Africa

Abstract: http://www.annals.org/article.aspx?doi=10.7326/M16-0799

URL goes live when the embargo lifts

A new study finds that implementing the United Nations targets for HIV testing and treatment would be an expensive but ultimately very cost-effective way to increase survival, reduce the number of children orphaned by HIV, and contain the global AIDS epidemic. That is the conclusion of researchers at the Massachusetts General Hospital (MGH), the University of Cape Town and the Yale School of Public Health, who estimated the likely impact of the so-called "90-90-90" program.