A tiny marine crustacean with a great big claw has shown that not only does size matter, but left or right-handedness (or in this case, left or right-clawedness) is important too.
The 5-6mm marine amphipod Dulichiella appendiculata, related to the land-based beach-hopper or sand flea we see hopping around on beaches, has one large claw on one side (either right or left), and a small claw on the opposite side.