One of the major obstacles with treating cancer is that tumors can conscript the body's immune cells and make them work for them. Researchers at EPFL have now found a way to reclaim the corrupted immune cells, turn them into signals for the immune system to attack the tumor, and even prevent metastasis.
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CANCER RESEARCH UK scientists have found a new way to slow the growth of the most aggressive type of breast cancer, according to research published in the journal Oncogene* today (Monday).
The team from Oxford University and the University of Nottingham found that using a drug called JQ1 can alter how cancer cells respond to hypoxia -- or low oxygen -- found in more than 50 per cent of breast tumours overall and most commonly in triple negative breast cancer, the form of the disease that is hardest to treat.
Irvine, Calif. -- The Botox toxin has a sweet tooth, and it's this craving for sugars - glycans, to be exact - that underlies its extreme ability target neuron cells in the body ... while giving researchers an approach to neutralize it.
UPTON, NY--A cube, an octahedron, a prism--these are among the polyhedral structures, or frames, made of DNA that scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have designed to connect nanoparticles into a variety of precisely structured three-dimensional (3D) lattices. The scientists also developed a method to integrate nanoparticles and DNA frames into interconnecting modules, expanding the diversity of possible structures.
The science of breeding chickens has revealed part of the mystery of how certain female animals are able to store sperm long-term. Droplets of fat transferred from female cells to sperm cells may contribute to keeping sperm alive.
Females of some types of insects, reptiles, and birds can store sperm from multiple males within specialized sperm storage areas of their reproductive tracts. Different animals can store sperm for days or years. Stored sperm can fertilize multiple eggs over time, meaning females do not need to mate again to fertilize additional eggs.
Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under investigated. Using a manually curated metabolic module framework for (meta-)genomic data analysis, Sara Vieira-Silva, Gwen Falony and colleagues from the Jeroen Raes lab (VIB/KU Leuven) studied species-function relationships in gut microbial genomes and microbiomes.
Amsterdam, June 13, 2016 - Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia.
NEW YORK (June 13, 2016) - Infection prevention bundles, a package of evidence-based guidelines implemented in unison, are effective for reducing central line-associated blood stream infections (CLABSI) in critical care newborn infants, according to a new study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America. The bundle helped reduce the number of lines placed, the duration of time used and the number of infections.
The microbiome is like a fingerprint: every person's community of microbes is complex and unique. But the underlying dynamics, the interactions between the microbes that shape these microbial ecosystems, may have something in common. To investigate, researchers from the Channing Division of Network Medicine at Brigham and Women's Hospital, led by Amir Bashan, PhD, and Yang-Yu Liu, PhD, analyzed data from large metagenomic datasets (e.g. the Human Microbiome Project and Student Microbiome Project) to look at the dynamics of the gut, mouth and skin microbiomes of healthy subjects.
Monrovia, CA (June 12, 2016) - Researchers are edging ever closer to discovering the perfect combination of drugs and drug delivery system that will stop the sexual transmission of HIV. Findings published last week in the journal PLOS ONE confirm that researchers from the Oak Crest Institute of Science, located in Monrovia, CA, have demonstrated for the first time that two powerful antiretroviral (AVR) drugs can provide complete protection against HIV when delivered topically by a sustained release intravaginal ring (IVR) device.
Low birth weight or stress during pregnancy can lead to long-term health problems in women, according to a study published today in The Journal of Physiology.
The study found that stress during pregnancy leads to long-term health issues in mothers, affecting adrenal, metabolic and cardio-renal health after pregnancy.
Jean Ni Cheong, from The University of Melbourne, and the PhD student leading the study, said it was known that being born of low birth weight or experiencing stress during pregnancy increased the risks of pregnancy complications.
A model that predicts outbreaks of zoonotic diseases -- those originating in livestock or wildlife such as Ebola and Zika -- based on changes in climate, population growth and land use has been developed by a UCL-led team of researchers.
An international team of scientists at EPFL and the US have discovered a material that can clear out radioactive waste from nuclear plants more efficiently, cheaply, and safely than current methods.
Although clinical trials have shown that lung cancer screening using low-dose computed tomography (LDCT) can detect lung cancers early and reduce lung cancer mortality, less than half of family physicians in a recent survey agreed that screening reduces lung cancer-related deaths. Most were also unaware of current recommendations on lung cancer screening in high risk patients. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings indicate that there are gaps physicians' knowledge about appropriate lung cancer screening.
For many, there's nothing like sitting down for a family meal at a table filled with hot, ready-to-serve food. Many caregivers enjoy providing diverse, nutritious meals to their families to be perceived as a good provider, and in some cultures, preparing excessive quantities of food is common. Think this is crazy? How many times have you had leftovers after Thanksgiving dinner?