SILVER SPRING, Md. - The Walter Reed Army Institute of Research (WRAIR), in collaboration with the Beth Israel Deaconess Medical Center and Harvard Medical School, has completed a second round of preclinical studies on a promising Zika vaccine candidate and found it to completely protect rhesus monkeys from experimental infection with Zika virus.
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Washington, DC--Women risk having their vitamin D levels fall when they stop using birth control pills or other contraceptives containing estrogen, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
Vitamin D is a hormone involved in the immune system and managing calcium levels in the blood. Proper calcium levels are necessary for bone health.
Washington, DC--Women who have polycystic ovary syndrome (PCOS)--a common cause of female infertility--may be able to improve their metabolic and cardiovascular health by consuming soy isoflavones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
Soy isoflavones are naturally occurring plant-based estrogens found in the soybean plant. They are found in foods such as soy milk, as well as supplements.
COLUMBUS, Ohio -- Researchers have uncovered previously hidden sources of ocean pollution along more than 20 percent of America's coastlines.
The study, published online Aug. 4 in the journal Science, offers the first-ever map of underground drainage systems that connect fresh groundwater and seawater, and also pinpoints sites where drinking water is most vulnerable to saltwater intrusion now and in the future.
Malignant cancer cells not only proliferate faster than most healthy cells in our bodies. They also generate more "junk", such as faulty and damaged proteins. This makes cancer cells inherently more dependent on the most important cellular garbage disposal unit, the proteasome, which degrades defective proteins and removes them from circulation. Treatments for some types of cancer, such as multiple myeloma -- a type of bone marrow cancer -- exploit this dependence. Patients are treated with inhibitors, which selectively block the proteasome.
BOSTON - A month after announcing that two promising vaccine candidates provided mice with complete protection against the Zika virus, a research team at Beth Israel Deaconess Medical Center (BIDMC), in collaboration with scientists at Walter Reed Army Institute of Research (WRAIR) and the University of São Paulo, now reports achieving complete protection against Zika virus in rhesus monkeys. The research team's findings were published online today in the journal Science.
Scientists working out of Trinity College Dublin, Maynooth University, and Queen Mary University of London have unearthed a potential new preventative option to combat Ascaris roundworm infection. Ascaris lumbricoides is an intestinal parasite that results in severe health consequences, including growth retardation and impaired cognitive development. The infection, which affects an estimated one billion people worldwide, is particularly common in Third World countries and is estimated to be responsible for 60,000 deaths per annum.
Scientists have tracked the flight paths of a group of bumblebees throughout their entire lives to find out how they explore their environment and search for food.
This is believed to be the first time any insect has been tracked throughout its whole life.
In this unconventional study, the researchers from Queen Mary University of London (QMUL) discovered the individual bumblebees differed greatly from one another in the way they flew around the landscape when foraging for nectar.
CAMBRIDGE, Mass. -- The cost and environmental impact of producing liquid biofuels and biochemicals as alternatives to petroleum-based products could be significantly reduced, thanks to a new metabolic engineering technique.
Liquid biofuels are increasingly used around the world, either as a direct "drop-in" replacement for gasoline, or as an additive that helps reduce carbon emissions.
WEST LAFAYETTE, Ind. - Alcohol-craving rats have provided researchers with a detailed look into the complicated genetic underpinnings of alcoholism.
By comparing the genomes of rats that drank compulsively with those that abstained, Purdue and Indiana University researchers identified 930 genes associated with alcoholism, indicating that it is a highly complex trait - on par with human height - influenced by many genes and the environment.
A new study from Autism Speaks' MSSNG program expands understanding of autism's complex causes and may hold clues for the future development of targeted treatments. The report, appearing in npj Genomic Medicine is the largest-ever whole genome study of autism, involving 200 children with the condition and both their unaffected parents.
Because the oceans absorb man-made carbon dioxide (CO2) from the atmosphere, its pH declines. Effects of this chemical change on tropical coral reefs can be examined in laboratory or short-term field experiments. However, a team led by Dr.
A group of Russian physicists, with the contribution from their Swiss colleagues, developed a way to use the therapeutic effect of heating or cooling the tissues due to the magnetocaloric effect. The article with the results of the work was published in the latest issue of the International Journal of Refrigeration.
A research team headed by investigators at the Icahn School of Medicine at Mount Sinai (ISMMS) has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell. They say the method, dubbed a "dual molecular tuner," offers an easy way to perform in-depth analyses in mammalian cells in general, and stem cells in particular.
WHAT:
Three different investigational Zika virus vaccine platforms--an inactivated virus vaccine, a DNA-based vaccine, and an adenovirus vector-based vaccine--protected against infection, induced immune responses, and produced no adverse side effects when tested in rhesus macaques challenged with the Zika virus, according to findings appearing August 4 in the journal Science. The results suggest that each of the three approaches holds promise for designing an effective Zika vaccine, according to the authors.