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Bottom Line: Young mice that received molecularly targeted therapies used to treat brain cancer in human patients sustained cognitive and behavioral deficits, but the deficits were largely reversible through environmental stimulation and physical exercise. The study suggests that pediatric brain cancer patients may experience similar side effects of molecularly targeted therapies, and may benefit from efforts to remediate any cognitive deficits.
Journal in Which the Study was Published: Cancer Research, a journal of the American Association for Cancer Research.
A new paper in Music Therapy Perspectives examines the importance of music therapy in military healthcare. There has been an increase in music therapy to treat combat-related injuries in recent years. With this growth in the use of the therapy, the authors of this article believe it’s important for practitioners to publish information about effective music therapy treatment models for use in military settings.
A new report finds that extremely obese people who have a band surgically strapped around their stomachs to restrict food intake not only lose weight but also suffer less from arthritic knee pain.
The pain, say the study leaders at NYU School of Medicine, proceeds from the deterioration and related inflammation in knee joints caused in part by the extra weight they bear. And while the pain relief seen with lap-band surgery applied to all patients with osteoarthritic knees, researchers found that it was most helpful in the youngest men and women who lost the most weight.
Amsterdam, March 20, 2018 - World meat consumption has increased during the last decades, and evidence is mounting that high consumption of red and mainly processed meat is unhealthy to humans and is related to chronic diseases such as cancer, type 2 diabetes, and cardiovascular disease. A new study published in the Journal of Hepatology adds non-alcoholic fatty liver disease (NAFLD) to the list.
BIRMINGHAM, Ala. - University of Alabama at Birmingham researchers have identified a therapeutic target to prevent or delay heart failure from pressure overload of the heart, and a potential biomarker for the same. They say their animal studies carry clinical and translational potential.
People with tough-to-treat triple negative breast cancer, whose tumors also don't allow for double-strand DNA repair, fare better when treated with a common adjuvant breast cancer chemotherapy combination, according to results from a SWOG clinical trial.
Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.
"There is a need for new methods of treatment for high-risk patients, and that's where our research can lead to truly great benefits," says Chandrasekhar Kanduri, professor of medical biochemistry and cell biology at Sahlgrenska Academy, Sweden.
Copenhagen: Many wives of advanced prostate cancer sufferers feel that their lives are being undermined by their husband's illness, with nearly half reporting that their own health suffered. In addition a focus subgroup has revealed that many feel isolated and fearful, and worry about the role change in their lives as their husband's cancer advances. This study, developed with the wives of men with metastatic prostate cancer who were being treated with hormone therapy, is amongst the first carried out on how prostate cancer affects the partners of sufferers.
CHICAGO--Children with obesity may be more impulsive than those with normal weight, but during family-based behavioral treatment (FBT), the more impulsive of children with obesity may lose more weight, a new study suggests. The results of the study will be presented in a poster on Sunday, March 18, at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.
FBT aims to change parent and child behaviors and is currently the recommended intervention for children with obesity.
The incidence of all cancers combined was similar for Métis men and significantly higher for Métis women compared to non-Aboriginal men and women, found a study published in CMAJ (Canadian Medical Association Journal)
CHICAGO -- Being obese or having a higher body mass index (BMI) while carrying a BRCA (BReast CAncer gene) mutation is positively linked with higher levels of damage to the DNA in normal breast gland cells, new research suggests. The results of the study will be presented Sunday, March 18, at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.
Obesity is a known risk factor for breast cancer, and breast cancer has been shown to occur more frequently in BRCA mutation carriers who are obese than in those who are lean.
CHICAGO--Breastfeeding may protect high-birthweight infants from having overweight or obesity as children, new research from South Korea suggests. The results will be presented in a poster on Sunday, March 18 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.
CHICAGO--Young women with premature ovarian insufficiency (POI) may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests. The preliminary results from the ongoing ROSE clinical trial will be presented Tuesday at ENDO 2018, the 100th annual meeting of the Endocrine Society, in Chicago, Ill.
CHICAGO--Using e-cigarettes may lead to an accumulation of fat in the liver, a study of mice exposed to the devices suggests. The research will be presented Sunday, March 18, at ENDO 2018, the Endocrine Society's 100th annual meeting in Chicago, Ill.
CHICAGO--Patients undergoing Roux-en-Y gastric bypass (RYGB) surgery may be at greater risk for non-vertebral fracture than those having adjustable gastric banding (AGB), a new population-based study reports. The results will be presented on Saturday, March 17 at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.