Body

Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan.

From a public health perspective, that advice would be impractical for many and dangerous for some.

By taking a high-cost drug with a low-fat meal--instead of on an empty stomach, as prescribed--prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent, according to a new study in the March 28, 2018, issue of the Journal of Clinical Oncology (JCO).

CLEVELAND, Ohio -- Today, most people in the United States rarely think of rheumatic heart disease (RHD)-or the rheumatic fever that causes it-as more than a historical footnote.

Rheumatic fever, which usually starts as strep throat, was essentially eliminated as a life-threatening disease with the use of penicillin in the early 20th century.

Belmont, MA - McLean Hospital neuroscientists have found that immune system activation during pregnancy and right at birth can cause alterations in the brain's neural circuits during young adulthood that are consistent with behavioral symptoms common in autism spectrum disorder (ASD) and other developmental conditions. The detailed findings are available in the March 28, 2018, issue of the Journal of Neuroscience.

After years of public health efforts, health care at the Los Angeles County Jail has significantly improved, and the facility now typically provides full access to treatment for inmates who have HIV -- including medications that keep their disease in check.

When they are released, however, many former inmates stop making regular visits to a doctor and taking the medication they need, which puts their own health at risk and increases the chance they will transmit the virus to others.

Bottom Line: Despite the steady increase of liver cancer incidence in the United States in recent decades, data from 2015 indicates that less than 13 percent of individuals born between 1945 and 1965 are estimated to have undergone screening for hepatitis C virus (HCV).

Journal in Which the Study was Published: Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

New research does not support the previously observed negative impacts of antidepressant use on breastfeeding. In the British Journal of Clinical Pharmacology study, use of serotonin reuptake inhibitors in late pregnancy was not linked with an increased risk of women experiencing low milk supply.

The study found that women with an underlying psychiatric illness appeared at greatest risk of experiencing low milk supply, however.

EAST LANSING, Mich. - Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.

These findings are based on two studies featured in the latest issue of Cancer Prevention Research.

In patients who have had a heart attack, the drug varenicline significantly reduced smoking during the following year, found a randomized controlled trial published in CMAJ (Canadian Medical Association Journal) .

Patients who smoke after an acute coronary syndrome, including a heart attack (myocardial infarction) or unstable angina (reduced blood flow to the heart) are at increased risk of another attack and death if they do not quit.

Alexandria, VA, USA - At the 47th Annual Meeting of the American Association for Dental Research (AADR), held in conjunction with the 42nd Annual Meeting of the Canadian Association for Dental Research (CADR), Teresa A. Marshall, University of Iowa College of Dentistry, Iowa City, presented an oral session titled "Associations Between Longitudinal Beverage Intakes and Adolescent Caries." The AADR/CADR Annual Meeting is in Fort Lauderdale, Fla., USA from March 21-24, 2018.

LA JOLLA, CA--In Type 1 diabetes the immune system mistakenly attacks and destroys insulin-producing pancreatic cells, leaving patients dependent on lifelong insulin injections. The putative perpetrators of the attack--which are called CD8+ cytotoxic T lymphocytes (CTLs)--recognize specific protein fragments displayed on pancreatic islet cells and then kill them. However, even CTLs that cannot recognize islet-specific antigens (but for example viral antigen) nonetheless invade pancreata as inflammation progresses.

When infectious diseases (ID) specialists were involved in the care of patients with certain kinds of drug-resistant infections, the patients' 30-day mortality rates were about 50 percent lower, according to a new study published in Open Forum Infectious Diseases. The findings provide additional evidence for the beneficial impact ID physicians have on patient care and outcomes, particularly when individuals have difficult to treat infections that are resistant to multiple antibiotics.

Barcelona, Spain: Women with small, low grade, well-defined breast tumours and a genetic profile that shows they are at low risk of the cancer metastasising have only a 1.4% risk of the cancer returning to the site of the original tumour or the nearby lymph nodes (known as locoregional recurrence) within five years, according to new results from a large randomised trial of nearly 7000 patients.

Barcelona, Spain: The average number of moderate or marked side-effects reported by breast cancer patients is lower if they are treated with radiotherapy to part of the breast or a reduced dose to the whole breast, rather than with standard radiotherapy to the whole breast, according to new findings presented at the 11th European Breast Cancer Conference on Friday.

Thousands of older people in low and middle-income countries are at risk of abuse and human rights violations when being admitted to care homes, according to new research led by the University of East Anglia (UEA).

The study provides the first systematic analysis of admissions practices for residential long-term care facilities, assessing the extent to which older people are involved in admission decisions and whether current practices respect fundamental human rights.