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Expanding the availability of medication treatment for opioid use disorder in primary care settings would be a major step toward reducing overdose deaths, write two physicians specializing in addiction medicine and health care delivery in the July 5 issue of New England Journal of Medicine.
Children of mothers who follow a healthy lifestyle have a substantially lower risk of developing obesity than children of mothers who don't make healthy lifestyle choices, finds a study published in The BMJ.
The findings show that risk was lowest among children whose mothers maintained a healthy weight, exercised regularly, did not smoke, ate a healthy diet, and were light to moderate drinkers.
New drugs known as direct oral anticoagulants (DOACs) used to treat serious blood clots are associated with reduced risks of major bleeding compared with the older anti-clotting drug, warfarin, finds a study in The BMJ today.
The findings provide initial reassurance about the safety of DOACs as an alternative to warfarin for all new patients.
Sepsis is an infection that kills as many Americans each year as stroke and Alzheimer's combined-about 250,000-but very little has changed in the treatment of this age-old scourge.
Now researchers at Columbia University Irving Medical Center have found a clue in understanding how an infection can spiral into sepsis by blunting the body's immune response. This research may also help doctors identify the patients who may need immediate intensive treatment to save their lives.
From Infection to Organ Failure
Charlottesville, VA (July 3, 2018). Researchers from the University of Michigan found that serum levels of two biomarkers of traumatic brain injury, tau and ubiquitin C-terminal hydrolase L1, are elevated following high-acceleration head impacts, even when there is no clinical diagnosis of concussion. Their complete findings are reported today in the Journal of Neurosurgery, in the article "Elevated markers of brain injury as a result of clinically asymptomatic high-acceleration head impacts in high-school football athletes" by Jacob R.
Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing
Anticonvulsant drugs are increasingly being used to treat low back pain, but a new study in CMAJ (Canadian Medical Association Journal) finds they are ineffective and can have adverse effects.
WHAT:
Fetal death in utero occurred in more than one-fourth of monkeys infected in the laboratory with Zika virus in early pregnancy, according to new research published in Nature Medicine. The finding raises the concern that Zika virus-associated pregnancy loss in humans may be more common than currently thought, according to the study authors.
New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center.
The scientists wanted to examine how cancers acquire resistance to treatment over time and whether those changes could be modeled computationally to determine patient-specific timelines of resistance.
The research was published by Genome Medicine on May 23, 2018.
Hospitals today spend a lot of time and effort to protect their patients from developing new infections while they're hospitalized - especially the most dangerous types that can threaten their health even more than the problem that sent them to the hospital in the first place. They also carefully track these hospital-acquired infections (HAIs), and even get paid more by the Medicare system if they achieve lower rates.
A multidisciplinary team from the University of Granada has developed software that can make it easier to identify potential pancreatic cancer biomarkers and thereby achieve earlier diagnosis of the disease. Pancreatic cancer can be diagnosed using biomarkers which, in this case, are differentially expressed genes indicative of this illness.
Australia's national science agency CSIRO has identified a new gene that plays a critical role in regulating the body's immune response to infection and disease.
The discovery could lead to the development of new treatments for influenza, arthritis and even cancer.
The gene, called C6orf106 or "C6", controls the production of proteins involved in infectious diseases, cancer and diabetes. The gene has existed for 500 million years, but its potential is only now understood.
A simple $20 blood test could help diagnose thousands of patients with hepatitis B in need of treatment in some of Africa's poorest regions.
Researchers have developed an accurate diagnostic score that consists of inexpensive blood tests to identify patients who require immediate treatment against the deadly hepatitis B virus - which can lead to liver damage or cancer (1).
Tokyo, Japan - Researchers from Tokyo Metropolitan University have observed the formation of holes that move by themselves in droplets of ionic liquids (IL) sitting inside water-ethanol mixtures. This curious, complex phenomenon is driven by an interplay between how ionic liquids dissolve, and how the boundary around the droplet fluctuates. Self-driven motion is a key feature of active matter, materials that use ambient energy to self-propel, with potential applications to drug delivery and nano-machine propulsion.
June 29, 2018 - Routine assessment by an endocrinologist and laboratory tests to measure hormone levels aren't necessary in most adolescent boys with gynecomastia (male breast enlargement), concludes a study in the July issue of Plastic and Reconstructive Surgery®, the official medical journal of the America
Deep brain stimulation (DBS) may slow the progression of tremor for early-stage Parkinson's disease patients, according to a Vanderbilt University Medical Center study released in the June 29 online issue of Neurology®, the medical journal of the American Academy of Neurology.
The study is the first evidence of a treatment that slows the progression of one of the cardinal features of Parkinson's, but a larger-scale clinical trial across multiple investigational centers is needed to confirm the finding.