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TORONTO, July 13, 2018 - Death due to cardiovascular disease is on the rise in India, causing more than one quarter of all deaths in the country in 2015 and affecting rural populations and young adults the most, suggests a study published today in The Lancet Global Health.
Bottom Line: A study of two generations of women in England examined how common depression during pregnancy (prenatal depression) is in young mothers now compared with their mothers' generation. Depressed mood was measured using self-reported surveys in both generations and analysis of the data suggests depression in young pregnant women may be higher now than among their mothers' generation in the 1990s. Researchers acknowledge a number of plausible explanations for their findings requiring further study.
BOSTON - Previous studies have shown that when all members of the clinical care team feel comfortable speaking up, team performance improves. With intimate knowledge of patients' wishes, medical histories and clinical conditions, patients and their families are increasingly considered crucial members of the optimal patient-centered care team. However, to have an impact on patient safety, patients and families must feel comfortable voicing concerns about care to the medical team.
AUGUSTA, Ga. (July 13, 2018) -When it comes to diagnosing a condition in which the plasma cells that normally make antibodies to protect us instead become cancerous, it may be better to look at the urine as well as the serum of our blood for answers, pathologists say.
The condition is monoclonal gammopathy, in which immune cells called plasma cells start making just one immunoglobulin, or antibody, instead of their usual vast array. The result can be the cancer multiple myeloma.
In areas of the country disproportionately affected by the opioid crisis, treatment programs are less likely to accept patients paying through insurance of any type or accept pregnant women, a new Vanderbilt study found.
Lebanon, NH - A new multi-institutional clinical trial compared outcomes of women with multiple ipsilateral breast cancer, or more than one site of disease in the same breast, who underwent breast-conserving surgery, with outcomes of those who converted to mastectomy. Out of 198 eligible women in the trial, 184 (92.9%) successfully completed breast-conserving surgery, 134 of those with a single operation.
New research published in Experimental Physiology has indicated potential differences in heart health benefits of exercise intensity in teenagers. Teenage years are an important stage of life, with research suggesting it is a time during which heart diseases start to develop. These findings indicate that teenagers who participate in high intensity exercise have lower blood pressure. This may lead to a lower risk of developing heart disease later in life, but this requires confirmation with further research.
Boston, MA -- Cancer immunotherapies and targeted therapy have revolutionized how clinicians take care of patients with advanced skin cancer and have led to long lasting treatment responses for many of them. However, little is known about the survival impact of these therapies for a substantial group of patients. Melanoma patients with cancer that has spread to the brain have been excluded or underrepresented in clinical trials of immunotherapies due to concerns about whether such drugs can cross the blood-brain barrier or will interfere with other forms of treatment.
Philadelphia, July 12, 2018-- A new study from a team of researchers at Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania School of Nursing (Penn Nursing) found that in the previous three months, about half of parents talked on a cell phone while driving when their children between the ages of 4 and 10 were in the car, while one in three read text messages and one in seven used social media.
Nearly a third of American adults have high blood pressure, also known as hypertension, putting them at higher risk for heart attacks, strokes, and death. A recent estimate from the Centers for Disease Control reports that high blood pressure--and the many conditions associated with it--contribute to over 400,000 deaths and cost the nation more than $40 billion each year.
ROCKVILLE, MARYLAND (JULY 11, 2018) --Aeras, a nonprofit organization dedicated to developing vaccines against tuberculosis (TB), today announced the publication of the full results from a Phase 2, randomized, controlled clinical trial of two TB vaccines-- the currently available BCG vaccine and an investigational vaccine, H4:IC31--in the New England Journal of Medicine (NEJM).
Peer-reviewed? Yes
Type of evidence: Observational
Subjects: People
Adopting new guidelines for high blood pressure (hypertension) would dramatically increase the number of people labeled as having the condition and being recommended for drug treatment, finds a study published by The BMJ today.
The findings show that, if the guidelines were introduced in the US and China, more than half of those aged 45-75 years in both countries would be considered hypertensive.
Peer-reviewed? Yes
Type of evidence: Observational
Subjects: People
Researchers report no increased risk of womb cancer or invasive breast cancer after assisted reproduction in a study of over 250,000 British women published by The BMJ today.
Small increased risks of non-invasive breast and ovarian tumours were found, but the researchers say these results may not be due to the treatment itself and require further investigation.
CINCINNATI - When a dangerous defect on chromosome 11q23 disrupts the genetic programming of blood cells, it causes an aggressive and deadly blood cancer called acute myeloid leukemia (AML). With a dismal survival rate of 20-40 percent and desperate need for better treatments, scientists at Cincinnati Children's report finding a potential therapeutic target for AML in preclinical laboratory tests on donated human cells and mice.