Body
Munich, Germany, 19 October 2018 - Nearly one in six premenopausal women being treated for early stage breast cancer do not adhere adequately to tamoxifen therapy after one year of treatment, potentially putting themselves at increased risk of recurrence and reduced survival, a French prospective study reports at ESMO 2018 (1).
Hormonal therapy such as tamoxifen is recommended for five to ten years in all patients with hormone receptor-positive breast cancer (2) but previous research has shown that many discontinue long-term therapy (3).
Munich, Germany, 19 October 2018 - Men and women may need to be treated differently - at least when it comes to some types of cancer. In an analysis (1) to be presented at the ESMO 2018 Congress in Munich, data was pooled from four UK randomised controlled clinical trials (RCTs) of first line chemotherapy in oesophagogastric (OG) cancer, finding significant differences in a number of important side-effects experienced by male and female patients.
Scientists at the University of York have found a way of distinguishing between fatal prostate cancer and manageable cancer, which could reduce unnecessary surgeries and radiotherapy.
A recent study showed that more than 25 men were being unnecessarily treated with surgery or radiotherapy, for every single life saved. It is believed that success rates could be hindered as a result of treating all prostate cancers in the same way.
-- Study from Australia is the first to evaluate a population-level roll-out of pre-exposure prophylaxis (PrEP) in men who have sex with men.
Rapid, targeted, and high-coverage roll-out of pre-exposure prophylaxis (PrEP) to men who have sex with men was associated with a reduction in HIV diagnoses by 25% in one year across New South Wales (Australia), according to a study published in The Lancet HIV journal.
Innovative cardioprotective strategies are of imminent demand. Nonfatal myocardial ischemia (MI) poses a significant risk to patients undergoing major non-cardiac surgery and these non-cardiac surgeries account for around 8 million myocardial injuries per year. Considering perioperative MI is the most common major cardiovascular complication, identifying factors that lead to cardiac disease onset and finding solutions to prevent potential cardiac damage are of critical importance.
Columbus, Ohio - A drug first identified 150 years ago and used as a smooth-muscle relaxant might make tumors more sensitive to radiation therapy, according to a recent study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).
ANN ARBOR--One question that scientists and fitness experts alike would love to answer is whether exercise or nutrition has a bigger positive impact on bone strength.
University of Michigan researchers looked at mineral supplementation and exercise in mice, and found surprising results--nutrition has a greater impact on bone mass and strength than exercise. Further, even after the exercise training stopped, the mice retained bone strength gains as long as they ate a mineral-supplemented diet.
ITHACA, N.Y. - Crohn's disease (CD), a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years. Experts have long suspected that CD likely represents a collection of related but slightly different disorders, but until now it has not been possible to predict accurately which subtype of CD a patient is likely to develop.
SAN FRANCISCO - Even with concerns about addiction, side effects and the other risks of opioids dominating headlines, a study presented at the ANESTHESIOLOGY® 2018 annual meeting found people expect to be prescribed opioids and perceive them to be the most effective form of pain relief after surgery. Interestingly, other research presented at the meeting found opioids led to complications such as increased pain, poorer quality of life and dependence following back surgery.
Terrorist attacks injure far more people than they kill, leaving victims with lost limbs, hearing loss, respiratory disease, depression and other issues. But little research has measured the impact of that damage beyond the number of people who are hurt.
Lugano-Munich, 12 October 2018 - Twitter is a place where many cancer patients go to share and discuss their experiences of the disease. This is the main finding of a recent exploratory study (1), to be presented at the ESMO 2018 Congress in Munich, which analysed the contents of over 6,000 tweets and retweets about breast cancer.
**Country-level data and spokespeople available**
Globally, 21% births are delivered via C-section, higher than the level thought required for medical purposes (10-15%).
60% of countries overuse C-sections, and 25% underuse the procedure, suggesting wide disparities in adherence to clinical recommendations.
Within countries large differences in use of C-sections exist between the rich and the poor, between public and private sectors, and between regions.
Genetics of puberty: Age at which women experience their first period linked to sons' age at puberty
The age at which young women experience their first menstrual bleeding is linked to the age at which their sons start puberty, according to the largest study to investigate this association in both sons and daughters.
The research, which is published today (Friday) in Human Reproduction [1], one of the world's leading reproductive medicine journals, looked at 15,822 children and found that the earlier women had their first period, the earlier their sons started puberty, and the later they had their first period, the later their sons started puberty.
The Philippines' highly politicised response to newly-reported risks of a dengue vaccine led to a dramatic drop in public trust in vaccines overall, according to new research published in Human Vaccines & Immunotherapeutics.
Led by the London School of Hygiene & Tropical Medicine (LSHTM), the study measured the impact of the Dengvaxia crisis on overall vaccine confidence before and after the manufacturer highlighted a risk associated with the vaccine and the associated political fallout.
BOSTON - (October 11, 2018) - People with type 1 diabetes are far more likely to develop cardiovascular disease than those without diabetes. Their risks climb even higher if they show signs of hypertension (high blood pressure) or dyslipidemia (unhealthy levels of cholesterol or triglycerides).
Interviewing both teens and parents, Joslin Diabetes Center researchers have identified strategies to help teens with these conditions manage them better, says Michelle Katz, MD, MPH, lead author on a paper about the work recently published in Pediatric Diabetes.