Body
CHAMPAIGN, Ill. -- Scientists at the University of Illinois have found that free fatty acids in the blood appear to boost proliferation and growth of breast cancer cells. The finding could help explain obese women's elevated risk of developing breast cancer after menopause.
"When taken up by estrogen-receptor positive breast cancer cells, these fatty acids activated pathways that increased tumor cell growth, survival and proliferation," said food science and human nutrition professor Zeynep Madak-Erdogan, who led the study.
First evidence that repeated mass administration of ivermectin can reduce malaria incidence in children aged five or younger without an increase in adverse events for the wider population given the drug.
Childhood malaria episodes could be reduced by 20% -- from 2.49 to 2 cases per child -- during malaria transmission season if the whole population were given a drug called ivermectin every three weeks, according to the first randomised trial of its kind including 2,700 people including 590 children from eight villages in Burkina Faso, published in The Lancet.
Women who find their jobs mentally tiring are more likely to develop type 2 diabetes, according to a study published in the European Journal of Endocrinology. The study findings suggest that mentally draining work, such as teaching, may increase the risk of diabetes in women. This suggests that employers and women should be more aware of the potential health risks associated with mentally tiring work.
A study of over 64,000 women of childbearing age in the USA has found that infertility is associated with a higher risk of developing cancer compared to a group of over three million women without fertility problems, although the absolute risk is very low at just 2%.
An imaging technique used to detect some forms of cancer can also help detect preeclampsia in pregnancy before it becomes a life-threatening condition, a new Tulane study says.
Preelcampsia is a hypertensive disorder that accounts for 14 percent of global maternal deaths annually and affects 5 to 8 percent of all pregnancies. Symptoms may include high blood pressure and protein in the urine and typically occurs after the 20th week of pregnancy.
ATLANTA--Youth living in the slums of Uganda who are infected with both HIV and sexually transmitted infections are more likely to engage in problem drinking, according to a study led by Georgia State University.
HIV prevalence among individuals living in Uganda is high (6.5 percent), and Uganda is one of the few countries where HIV rates are increasing rather than decreasing. However, HIV prevalence is even higher among youth living in the slums of Kampala. They are vulnerable because of food scarcity, lack of parental oversight and limited infrastructure.
According to the American Cancer Society, prostate cancer is the second most common cause of cancer-related death among men in the United States in 2018. Currently, the standard of care treatment for high-risk, localized prostate cancer is a combination of radiotherapy (RT) and long-term (24-36 month) androgen suppression (AS). Researchers theorized that adding adjuvant docetaxel, a cytotoxic chemotherapy drug, to the standard of care RT and long-term AS treatment could potentially improve overall survival and clinical outcomes for men with localized, high-risk prostate cancer.
DURHAM, N.H. - Researchers at the University of New Hampshire are one step closer to helping answer the question of why autism is four times more common in boys than in girls after identifying and characterizing the connection of certain proteins in the brain to autism spectrum disorders (ASD).
Standard tests used to identify dehydration are not working for older people living in care homes - according to new research from the University of East Anglia.
Carers often use simple tests to see if an older person is dehydrated. These include looking at their eyes, skin, or asking if someone feels thirsty, tired or has a headache.
But new research published today finds that these tests do not accurately identify dehydration in older people, when compared against 'gold standard' blood tests.
NHS-approved PARP inhibitor therapy found to boost the body's immune response
Drugs could be used to increase number of patients who respond to immunotherapies
Treatment developed for ovarian and breast cancers could also work in some lung cancers
Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals.
WASHINGTON--Researchers will explore the link between unhealthy snack intake and screen time, long-term opioid use and its impact on men's testosterone levels, and other emerging science during news conferences at ENDO 2019, the Endocrine Society's annual meeting taking place March 23-26 in New Orleans, La.
The Society is debuting two new Clinical Practice Guidelines at the news conferences, which will be webcast at endowebcasting.com.
News Conference Schedule:
Saturday, March 23
New research suggests two-thirds (67%) of pregnant women in London aged between 16 and 24 years have mental health problems including depression, anxiety disorders, post-traumatic stress disorder and obsessive compulsive disorder, according to new research funded by the National Institute for Health Research (NIHR). Anxiety disorders, in particular social phobia, are especially high.
By comparison, the research suggests roughly one in five (21%) pregnant women in London aged 25 years and over have mental health problems.
An estimated 15 to 20 percent of all breast cancer patients are "triple negative." These unfortunate women lack three crucial treatment targets--the estrogen receptor, the progesterone receptor and human epidermal growth factor receptor 2. Because they lack these targets, most triple negative patients are treated with standard chemotherapy, rather than the preferred targeted drugs. Triple negative breast cancer (TNBC) also disproportionately affects younger women, women of African descent and women with mutations in the BRCA1 gene.
PHILADELPHIA - When cancer spreads to another organ, it most commonly moves to the liver, and now researchers at the Abramson Cancer Center of the University of Pennsylvania say they know why. A new study, published today in Nature, shows hepatocytes - the chief functional cells of the liver - are at the center of a chain reaction that makes it particularly susceptible to cancer cells.
Infants who are admitted to hospital with the common infection bronchiolitis are at increased risk of further emergency hospital admissions for asthma, wheezing and respiratory illness in the first five years of their life.
These are the findings of researchers from Imperial College London, who tracked 613,377 babies (almost all births in England between April 2007 - March 2008) up to the age of five years. Around 16, 000 babies were admitted to hospital with bronchiolitis before their first birthday.