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ARLINGTON HEIGHTS, IL - (APRIL 2, 2019) - Allergy shots (subcutaneous immunotherapy or SCIT) have been available for more than 100 years. Allergy tablets (sublingual immunotherapy or SLIT) have been approved by the Food and Drug Administration (FDA) for use in the United States for four years. A new study in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI) shows that most American allergists now prescribe the tablets for some patients to treat certain allergies.
New Rochelle, NY, April 1, 2019--Modern medicines have positively contributed to public health and changed the ways human diseases are prevented and treated. Yet, most drugs are not without side effects. Adverse drug reactions (ADRs) rank among the leading causes of morbidity and mortality worldwide. The current paradigm of drug development can detect only the most common ADRs in clinical trials.
ATLANTA -- A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according to results from a phase I clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3.
ATLANTA -- A combination of the anti-CTLA-4 immunotherapeutic ipilimumab (Yervoy) and the anti-PD-1 immunotherapeutic nivolumab (Opdivo) showed clinical benefit among patients with rare, high-grade neuroendocrine carcinoma, according to results from the DART phase II clinical trial presented at the AACR Annual Meeting 2019, March 29-April 3.
ATLANTA --Excess weight before age 50 may be more strongly associated with pancreatic cancer mortality risk than excess weight at older ages, according to results of a study presented at the AACR Annual Meeting 2019, March 29-April 3.
(PHILADELPHIA) - Glioblastoma is the most aggressive type of primary brain cancer, one with a prognosis of 11-15 months with standard treatment. Results from a phase 1b clinical trial of a new experimental glioblastoma vaccine developed by Jefferson and Imvax, show the treatment was tolerated well by patients, slowed tumor recurrence, and prolonged patient survival.
Researchers at the University of Illinois at Chicago have found that some preterm babies born without haptoglobin, a protein in blood cells, have higher odds of brain bleeding, cerebral palsy and death. Their findings suggest that the absence of the protein could serve as a potential biomarker indicating a need for increased monitoring or other preventive interventions.
As increasing numbers of patients gain online access to their radiology reports, a new study published in the April 2019 issue of the American Journal of Roentgenology (AJR) assesses how thoroughly patients understand these complex documents.
An essential part of breast intervention is the process of assessing concordance between imaging findings and core biopsy results. When pathology results are considered benign discordant, current standard of care is surgical excision, even though many of these lesions will ultimately be found benign.
A new study published in the April 2019 issue of the American Journal of Roentgenology (AJR) investigates whether including contrast-enhanced MRI in the assessment process might significantly benefit patient care.
TORONTO, March 29, 2019 -- Researchers at the University of Toronto and The Hospital for Sick Children (SickKids) have teamed up with educators, public health practitioners and grade seven students in Ontario to develop and implement a new approach to delivering school-based vaccines that improves student experience.
Some diseases which are fatal in one species can cause only mild discomfort in another--but it's hard for scientists to predict how lethal a disease will be if it leaps across species.
However, a new paper published this week in the Proceedings of the National Academy of Sciences indicates that the evolutionary relationship between infected hosts can predict the impact of diseases.
Canadian researchers used data from the World Organisation for Animal Health to track diseases in domesticated mammals, tracing their paths and outcomes across the world.
Preterm infants must establish regular breathing patterns at delivery. For extremely preterm infants requiring resuscitation at birth, a ventilation strategy involving two sustained inflations, compared with standard intermittent positive pressure ventilation, did not reduce the risk of bronchopulmonary dysplasia (BPD) or death at 36 weeks postmenstrual age.
Newton, Mass. (March 26, 2019) - Being a gymnast has its risks--the countless jumps, twists, and landings can take a toll on the body. But there's another, invisible risk: the equipment used in training contains hazardous flame retardant chemicals that accumulate in air and dust, and eventually end up in the athletes' bodies. A new study, however, shows that replacing the foam cubes in the landing pits with flame retardant-free alternatives can significantly lower their exposures.
AUSTIN, TEXAS (March 25, 2019)-- Uterine fibroid embolization (UFE) effectively treats uterine fibroids with fewer post-procedure complications compared to myomectomy, according to new research presented today at the Society of Interventional Radiology's 2019 Annual Scientific Meeting. Women who received this minimally-invasive treatment also had a slightly lower need for additional treatment than those who underwent surgery.
AUSTIN, TEXAS (March 24, 2019)--Tennis elbow, the painful chronic condition that affects up to 3 percent of the U.S. adult population, can be effectively treated through transcatheter arterial embolization (TAE), an image-guided, non-surgical treatment that decreases abnormal blood flow to the injured area to reduce inflammation and pain, according to research presented today at the Society of Interventional Radiology's 2019 Annual Scientific Meeting.