Body
Osaka, Japan - Long-term dialysis treatment is tough on the body in many ways, but one of the most serious complications is dialysis-related amyloidosis, a disease characterized by abnormal buildup of protein aggregates--called amyloid fibrils--in joints, tissues and organs.
Although there is no cure, recent research by Osaka University researchers sheds light on how amyloid fibrils form and aggregate, thereby allowing the identification of new therapeutic and preventive avenues to further improve the lives of sufferers.
Medicinal cannabis oil containing both cannabidiol (CBD) and a small amount of THC can reduce or end seizures in children with severe, drug-resistant epilepsy, a study by the University of Saskatchewan (USask), Canada has found.
Children with severe epilepsy also experienced improvements in their quality of life after taking low doses of the medicinal cannabis oil, according to research published in Frontiers in Neurology.
PHILADELPHIA - For patients with prostate cancer, treating the disease with androgen deprivation therapy (ADT) is linked to a higher likelihood of being diagnosed with Alzheimer's disease or dementia, compared to patients who do not receive the therapy, according to a study from researchers in the Perelman School of Medicine at the University of Pennsylvania. The results were published this week in JAMA.
DALLAS, July 8, 2019 -- Microvascular disease is independently associated with a higher risk of leg amputation compared to people without the disease, according to new research in the American Heart Association's journal Circulation.
A new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, shows that women of color and young women may face elevated risks of developing triple-negative breast cancers, which are often aggressive and do not respond to hormone therapy or targeted therapy.
Barcelona, Spain, 6 July 2019 - Medical oncologists administer anticancer drug regorafenib to try to improve overall survival in patients with metastatic colorectal cancer who have ceased to respond to standard therapy (known as refractory mCRC). However, some of the adverse events related to the use of this drug often limits its use in clinical practice. A study reported at the ESMO World Congress on Gastrointestinal Cancer 2019 suggests the usefulness of a more flexible dosing, which improves patients' quality of life without jeopardising efficacy. (1,2)
What The Study Did: This study used measures of implicit and explicit biases to assess how health care professionals associated men and women with career and family, and how surgeons associated men and women with surgery and family medicine.
Authors: Arghavan Salles, M.D., Ph.D., of Washington University in St. Louis, is the corresponding author.
(doi:10.1001/jamanetworkopen.2019.6545)
MINNEAPOLIS - A study of high school and college football players suggests that biomarkers in the blood may have potential use in identifying which players are more likely to need a longer recovery time after concussion, according to a study published in the July 3, 2019, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A new review of evidence from the UK has found high levels of alcohol dependence among hospital inpatients. The researchers estimate one in five patients in the UK hospital system uses alcohol harmfully, and one in ten is alcohol dependent.
Currently little is being done to screen routinely for alcohol dependence in hospitals, and services for patients with alcohol dependence are limited. The researchers call for universal screening in hospitals for alcohol-related problems and improved training for hospital staff around alcohol-related conditions.
People with a genetic predisposition to obesity are not only at greater risk of excess weight, their genes interact with an increasingly "obesogenic" environment, resulting in higher body mass index (BMI) in recent decades, finds a study from Norway published by The BMJ today.
But the findings also show that BMI has increased for both genetically predisposed and non-predisposed people since the 1960s, implying that the environment remains the main contributor to the obesity epidemic.
Using advanced technology, scientists at Chan Zuckerberg (CZ) Biohub, Mayo Clinic and University of California, San Francisco (UCSF), have discovered an autoimmune disease that appears to affect men with testicular cancer.
An analysis of samples obtained from a well-studied cohort of over 1,000 patients affected by type 1 diabetes (T1D) for 50 years or longer has identified a protein that protects against an eye condition called diabetic retinopathy (DR) - one of the most common consequences of diabetes - which impacts most diabetic patients after 20 years of living with the disease. Injecting the protein into rodents blocked DR without causing severe side effects, suggesting that preserving or administering the protein could help avoid debilitating eye damage in diabetic patients.
Bottom Line: Data for 154,089 older men diagnosed with prostate cancer were used to analyze the association between androgen deprivation therapy, a hormone-suppressing therapy used to treat prostate cancer, and subsequent diagnosis of Alzheimer disease or dementia. Of the men, 62,330 (average age 76) received androgen deprivation therapy within two years of being diagnosed with prostate cancer and 91,759 men (average age 74) didn't have such treatment.
Gestational hypertension -- high blood pressure during pregnancy -- can have persisting adverse effects on the health of mothers and their infants. In 2017, the American College of Cardiology (ACC) and the American Heart Association (AHA) released clinical guidelines for hypertension in non-pregnant adults, which lowered the blood pressure threshold to diagnose hypertension, compared to previously established ones. However, the new ACC/AHA guidelines have not been adapted or applied to pregnant women.
New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK*, and excess weight causes more cases of certain cancers than smoking, as the charity urges Government action to tackle obesity.
Almost a third of UK adults are obese** and, while smoking is still the nation's biggest preventable cause of cancer and carries a much higher risk of the disease than obesity, Cancer Research UK's analysis revealed that being overweight or obese trumps smoking as the leading cause of four different types of cancer***.