Growing evidence suggests that accumulation of multiple alterations such as activation of proto-oncogenes and inactivation of tumor suppressor genes is responsible for the development and progression of digestive system cancer. Genetic instability of oncogenes such as microsatellite instability (MSI) and loss of heterozygosity (LOH) is probably associated with mutations in genes responsible for tumor-genesis, and they play important roles in tumor clinical pathology.
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New research shows that most children have a diet that contains enough essential vitamins and minerals.
Analysis of the Government's own survey of children's diets and nutritional status has shown that the average child gets the recommended level of most vitamins and minerals, even though they consume more added sugars than recommended.
According to a new analysis published September 24th in the open-access journal PLoS Neglected Tropical Diseases, "The Neglected Tropical Diseases of Latin America and the Caribbean: A Review of Disease Burden and Distribution and a Roadmap for Control And Elimination,", neglected tropical diseases (NTDs) as a group may have surpassed HIV/AIDS, tuberculosis and malaria as the most prevalent infectious diseases in Latin America and the Caribbean. The analysis found that NTDs are the most common infections of approximately 200 million of the poorest people in the region.
Professors Yiqi Luo, Linda Wallace and Rebecca Sherry in the Department of Botany and Microbiology coauthored a paper with colleagues Jay Arnone and Paul Verburge at the Desert Research Institute; Dale Johnson from the University of Nevada at Reno; David Chimel from the National Center for Atmospheric Research; and others to report their findings on the long-term effects of warming anomaly on grassland productivity and ecosystem carbon cycling.
DANVILLE, PA. – Finding better ways to deliver healthcare to patients is key to ensuring that Medicare is able to meet the needs of the nation's baby boomers according to a new paper by Geisinger Health System published in Health Affairs.
Speaking at the 10th anniversary conference of the Swiss Institute ofBioinformatics in Berne, Switzerland, its director Professor Ron Appeldescribed his institute as a "Swiss success story". He said that he wasproud that as pioneers at the heart of science one of the SIB's 25 workinggroups was today able to announce the completion of the annotation ofhuman proteins.
Professor Amos Bairoch, head of the SIB's Swiss-Prot group said: "If humanDNA is the script of life, proteins are its actors, its living embodiment."
Sept. 23, 2008 -- Cancer death rates in the United States are highest among African Americans, but a new report shows that in Missouri the disparity in cancer incidence and death between African Americans and whites is declining. As a result, cancer incidence (the rate of newly diagnosed cases) between the races is equal, although the death rate will probably remain higher for African Americans for some time.
The genome of a humble worm that dines on the microbial organisms covering the carcasses of dead beetles may provide clues to the evolution of parasitic worms, including those that infect humans, say scientists at Washington University School of Medicine in St. Louis and the Max-Planck Institute for Developmental Biology in Germany.
In a paper published in the current issue of Nature Genetics, the researchers reported finding some surprises as they have decoded the genome of the worm, a tiny nematode called Pristionchus pacificus.
PORTLAND, Ore. – Oregon Health & Science University researchers have determined exactly how much breathing affects prostate movement during radiation treatment.
The results of this research are being presented from 5 p.m. to 6:30 p.m. today at the 50th annual American Society for Therapeutic Radiology and Oncology in Boston.
Johns Hopkins scientists who have spent decades researching the effects of caffeine report that a slew of caffeinated energy drinks now on the market should carry prominent labels that note caffeine doses and warn of potential health risks for consumers.
Queen's researchers have found that the main source of food for many fish - including cod - in the North Atlantic appears to adapt in order to survive climate change.
Billions of Calanus finmarchicus, a plankton species, which are just a few millimetres in size, live in the waters of the North Atlantic where the research was carried out.
The burden of trachoma in Ayod county, one of the most severe ever documented, is a threat to public health in Southern Sudan, according to a recent survey conducted in Jonglei state. These results, published September 24th in the open-access journal PLoS Neglected Tropical Diseases, were uncovered by experts at The Carter Center and University of Cambridge, and health officials from the government of Southern Sudan. The research determines the extent of the problem and resources needed to eliminate blinding trachoma from the county.
A dietary supplement containing isoflavone – a chemical found in soybeans, chickpeas, legumes and clovers – can improve artery function in stroke patients according to new research published online in Europe's leading cardiology journal, the European Heart Journal [1] today (Wednesday 24 September).
PITTSBURGH, Sept. 23 – Resveratrol, the natural antioxidant commonly found in red wine and many plants, may offer protection against radiation exposure, according to a study by the University of Pittsburgh School of Medicine. When altered with acetyl, resveratrol administered before radiation exposure proved to protect cells from radiation in mouse models. The results of the research will be presented during the American Society for Therapeutic Radiology and Oncology's (ASTRO) 50th Annual Meeting in Boston.
Researchers have developed and validated a model that predicts relapse in women with stage 2 or 3 breast cancer who have been treated with endocrine therapy prior to surgical removal of the tumor, according to a study published online September 23 in the Journal of the National Cancer Institute. The preoperative endocrine prognostic index (PEPI) may help identify women who can safely avoid chemotherapy and those women at high risk of relapse who should be considered for aggressive therapy.