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Using phage to discover new antifreeze proteins

Eurekalert - May 11 2021 - 00:05
Controlling, and mitigating the effects of ice growth is crucial to protect infrastructure, help preserve frozen cells and to enhance texture of frozen foods. An international collaboration of Warwick Scientists working with researchers from Switzerland have used a phage display platform to discover new, small, peptides which function like larger antifreeze proteins. This presents a route to new, easier to synthesise, cryoprotectants.
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Map of metabolic changes after heart attack holds clues to recovery

Eurekalert - May 11 2021 - 00:05
Researchers have mapped out the changes in metabolism that occur after a heart attack, publishing their findings today in the open-access eLife journal.
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University of Miami researchers report COVID-19 found in penile tissue could contribute to ED

Eurekalert - May 11 2021 - 00:05
University of Miami Miller School of Medicine researchers are the first to demonstrate endothelial dysfunction that results from the COVID-19 infection could contribute to erectile dysfunction.
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New gene editing strategies developed for Duchenne muscular dystrophy

Eurekalert - May 11 2021 - 00:05
DALLAS - April 30, 2021 - UT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD), uniquely utilizing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein that is missing in many DMD patients. The approach, described online today in the journal Science Advances, could lead to a treatment for DMD and inform the treatment of other inherited diseases.
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Researchers use AI to identify a new bone shape measure in knee osteoarthritis

Eurekalert - May 11 2021 - 00:05
Using an Artificial Intelligence-based approach known as deep learning, researchers from Boston University School of Medicine (BUSM) have now identified a new measure to determine the severity of knee osteoarthritis--named "subchondral bone length" (SBL).
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Researchers identify genes responsible for loss of lung function

Eurekalert - May 11 2021 - 00:05
Researchers from Boston University School of Medicine (BUSM) have identified a panel of genes that are active in smokers and ex-smokers who experience faster loss of lung function over time. They believe these genes could be useful to predict which people are most at risk for smoking-related decline in lung function.
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Roads pose significant threat to bee movement and flower pollination, U-M study shows

Eurekalert - May 11 2021 - 00:05
Road networks extend some 20 million miles across the globe, and that number is projected to increase by an additional 15 million miles or so by 2050.
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Ventilation assessment by carbon dioxide levels in dental treatment rooms

Eurekalert - May 11 2021 - 00:05
Carbon dioxide (CO2) is a byproduct of human metabolism and exists in high levels in exhaled air, and is therefore often used as a proxy for indoor air quality. The study "Ventilation Assessment by Carbon Dioxide Levels in Dental Treatment Rooms," published in the Journal of Dental Research (JDR), evaluated CO2 levels in dental operatories and determined the accuracy of using CO2 levels to assess ventilation rate in dental clinics.
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AI analytics predict COVID-19 patients' daily trajectory in UK intensive care units

Eurekalert - May 11 2021 - 00:05
Researchers used AI to identify which daily changing clinical parameters best predict intervention responses in critically ill COVID-19 patients.
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New USask research will make bean crops hardier, help improve global food security

Eurekalert - May 11 2021 - 00:05
Tepary beans--a high protein legume common to the southwest United States and Mexico--may hold the key to adapting bean crops for the increasingly harsh conditions brought on by a changing climate, according to research led by University of Saskatchewan (USask) and Michigan State University.
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COVID-19 wastewater testing proves effective in new study

Eurekalert - May 11 2021 - 00:05
The research offers some of the first clear guidance on the most effective methods to perform testing to detect COVID-19 in wastewater.
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A scientist from HSE University has developed an image recognition algorithm

Eurekalert - May 11 2021 - 00:05
A scientist from HSE University has developed an image recognition algorithm that works 40% faster than analogues. It can speed up real-time processing of video-based image recognition systems. The results of the study have been published in the journal Information Sciences.
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New ancient shark discovered

Eurekalert - May 11 2021 - 00:05
In a new study, an international team led by Sebastian Stumpf from the University of Vienna describes a fossil skeleton of an ancient shark, which is assigned to a new, previously unknown genus and species.
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In the blood: Which antibodies best neutralize the coronavirus in COVID-19 patients?

Eurekalert - May 11 2021 - 00:05
Blood tests to detect antibodies against SARS-CoV-2, the virus that causes COVID-19, are an important tool for diagnosing the disease, developing potential treatments, and checking vaccine efficacy. Although such tests are available, we have very little understanding on how different antibodies interact with virus antigens. Scientists from Fujita Health University set out to assess various antigen-specific antibodies and determined which of them had the strongest neutralizing activity against SARS-CoV-2.
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Adolescence is a window of opportunity for improving health literacy

Eurekalert - May 11 2021 - 00:05
A study by the University of Southampton has shown its LifeLab programme, aimed at improving adolescent health through hands-on learning, significantly increases young people's understanding of what it means to lead a healthy lifestyle.
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Better treatment for miscarriage patients is more cost effective than standard NHS treatment

Eurekalert - May 11 2021 - 00:05
A new drug combination that is better at treating miscarriage is also more cost effective than current standard NHS treatment, finds a new study led by the University of Birmingham and Tommy's National Centre for Miscarriage Research.
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Transferability of surface-functionalized metallic nanoparticles

Eurekalert - May 11 2021 - 00:05
Announcing a new article publication for BIO Integration journal. In this review the authors Muhammad Arif Asghar, Rabia Ismail Yousuf, Muhammad Harris Shoaib, Muhammad Arif Asghar and Nazish Mumtaz from Jinnah Sindh Medical University, Karachi, Pakistan, University of Karachi, Karachi, Pakistan, Food and Marine Resources Research Centre, Pakistan and Benazir Bhutto Shaheed University, Karachi, Pakistan discuss toxicity and challenges in transferability of surface-functionalized metallic nanoparticles from animal models to humans.
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Online CBT effective against OCD symptoms in the young

Eurekalert - May 11 2021 - 00:05
Obsessive-compulsive disorder (OCD) in children and adolescents is associated with impaired education and worse general health later in life. Access to specialist treatment is often limited. According to a study from Centre for Psychiatry Research at Karolinska Institutet in Sweden and Region Stockholm, internet-delivered cognitive behavioural therapy (CBT) can be as effective as conventional CBT. The study, published in the prestigious journal JAMA, can help make treatment for OCD more widely accessible.
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Coral reef restorations can be optimized to reduce flood risk

Eurekalert - May 11 2021 - 00:05
A new study sets out guidelines to maximize the benefits of reef restoration, not only for the coral ecosystem, but also to protect local communities from coastal flooding. Researchers simulated waves travelling over different reef profiles at various stages of restoration and found that to reduce the risk of flooding, the upper fore reef and middle reef flat, typically characterized by physically-robust coral species, should be targeted for restoration.
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Gout treatment success doubled by combining two drugs, study finds

Eurekalert - May 11 2021 - 00:05
If left untreated, gout can cause severe disability. But unlike rheumatoid arthritis, there are only a handful of ways to treat it. Researchers say a combination of two existing drugs disrupts antibody production and doubles treatment efficacy.
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