Science 2.0

Knee Point Prediction And Battery Capacity Degradation

Science 2.0 - Dec 03 2024 - 11:12
Electric cars and solar and wind energy alternative schemes have a few crippling limitations; low energy densities and unavailability when people need energy most. Batteries could help with that second one except current batteries are legacy technology that are held back by subsidies and mandates, not improved.

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MicroRNA And The Microprocessor Inside You

Science 2.0 - Dec 03 2024 - 11:12
Since being discovered in 1993, microRNAs have gone on to win a Nobel Prize in Physiology or Medicine, thanks to private sector uptake with the COVID-19 vaccines that saved the world during the pandemic that emerged from Wuhan, China in early 2020. 

Errors in the manufacture of over 1,000 microRNAs can put us at risk for developmental disorders, cancer, or neurodegenerative disease and a new study looks at a molecular machine called Microprocessor (MP), which trims longer molecules called primary microRNAs (pri-miRNAs) - without cutting other kinds of RNA that resemble pri-miRNAs.

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Categories: Science 2.0

MicroRNA And The Microprocessor Inside You

Science 2.0 - Dec 03 2024 - 11:12
Since being discovered in 1993, microRNAs have gone on to win a Nobel Prize in Physiology or Medicine, thanks to private sector uptake with the COVID-19 vaccines that saved the world during the pandemic that emerged from Wuhan, China in early 2020. 

Errors in the manufacture of over 1,000 microRNAs can put us at risk for developmental disorders, cancer, or neurodegenerative disease and a new study looks at a molecular machine called Microprocessor (MP), which trims longer molecules called primary microRNAs (pri-miRNAs) - without cutting other kinds of RNA that resemble pri-miRNAs.

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Kitchen Countertops Are Giving You Cancer

Science 2.0 - Dec 02 2024 - 13:12
“This is a new and emerging epidemic, and we must increase awareness of this disease process so we can avoid delays in diagnosis and treatment for our patients,” says University of California in Los Angeles radiology resident Sundus Lateef, M.D.

Epidemic? Again? No.

Americans are now so healthy that we have migrated from promoting nonsensical fear about virtual pollution (PM2.5) and weedkillers and lumber all the way down to...kitchen countertops.

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Categories: Science 2.0

Kitchen Countertops Are Giving You Cancer

Science 2.0 - Dec 02 2024 - 13:12
“This is a new and emerging epidemic, and we must increase awareness of this disease process so we can avoid delays in diagnosis and treatment for our patients,” says University of California in Los Angeles radiology resident Sundus Lateef, M.D.

Epidemic? Again? No.

Americans are now so healthy that we have migrated from promoting nonsensical fear about virtual pollution (PM2.5) and weedkillers and lumber all the way down to...kitchen countertops.

read more

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Tracking Particles With Neuromorphic Computing

Science 2.0 - Dec 01 2024 - 15:12
At the IV Workshop in Valencia a student from my group, Emanuele Coradin, presented the results of a novel algorithm for the identification of charged particles in a silicon tracker. The novelty is due to the use of neuromorphic computing, which works by encoding detector hits in the time of arrival of current impulses at neurons, and by letting neurons "learn" the true patterns of hits produced by charged particles from the noise due to random hits.

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Categories: Science 2.0

Tracking Particles With Neuromorphic Computing

Science 2.0 - Dec 01 2024 - 15:12
At the IV Workshop in Valencia a student from my group, Emanuele Coradin, presented the results of a novel algorithm for the identification of charged particles in a silicon tracker. The novelty is due to the use of neuromorphic computing, which works by encoding detector hits in the time of arrival of current impulses at neurons, and by letting neurons "learn" the true patterns of hits produced by charged particles from the noise due to random hits.

read more

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Electric Cars Have Killed Nissan

Science 2.0 - Nov 27 2024 - 15:11
Their Infiniti car couldn't ruin Nissan, but a climate where government mandates and subsidizes electric cars, which means deviating down to the revenue and running lean, are going to put them out of business. 

Because they were the world's largest electric car company, and they foolishly believed politicians who said if government forced the product on people, a miracle of capitalism would occur and consumers would like it.


Leaf. Credit: Nissan.

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Categories: Science 2.0

Electric Cars Have Killed Nissan

Science 2.0 - Nov 27 2024 - 15:11
Their Infiniti car couldn't ruin Nissan, but a climate where government mandates and subsidizes electric cars, which means deviating down to the revenue and running lean, are going to put them out of business. 

Because they were the world's largest electric car company, and they foolishly believed politicians who said if government forced the product on people, a miracle of capitalism would occur and consumers would like it.


Leaf. Credit: Nissan.

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Marijuana For ADHD?

Science 2.0 - Nov 27 2024 - 15:11
Cannabis and THC, its main psychoactive compound, have been endorsed by people suffering from anxiety, sleep problems, epilepsy, and cancer pain.

What is missing from such claims is a plausible biological hypothesis for how it can be everything to everyone, which means scientifically it is still just a placebo.

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Categories: Science 2.0

Marijuana For ADHD?

Science 2.0 - Nov 27 2024 - 15:11
Cannabis and THC, its main psychoactive compound, have been endorsed by people suffering from anxiety, sleep problems, epilepsy, and cancer pain.

What is missing from such claims is a plausible biological hypothesis for how it can be everything to everyone, which means scientifically it is still just a placebo.

read more

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If You Like Thanksgiving, Thank Capitalism

Science 2.0 - Nov 27 2024 - 12:11
Europeans who emigrated to the colonies in America had a dream of religious freedom, denied to them by European elites and government-mandated beliefs, and legal equality, absolutely impossible in England if you were poor, but they also believed in an economic Utopia.


That last belief nearly cost them their lives. William Bradford, the first leader of that Massachusetts Bay colony, eventually conceded their socialist ideal failed. Free riders who chose not to work nearly doomed them. By 1621, a year after landing in Massachusetts, they had changed from socialism to a system where each family owned their land and worked it for their family.

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Categories: Science 2.0

If You Like Thanksgiving, Thank Capitalism

Science 2.0 - Nov 27 2024 - 12:11
Europeans who emigrated to the colonies in America had a dream of religious freedom, denied to them by European elites and government-mandated beliefs, and legal equality, absolutely impossible in England if you were poor, but they also believed in an economic Utopia.


That last belief nearly cost them their lives. William Bradford, the first leader of that Massachusetts Bay colony, eventually conceded their socialist ideal failed. Free riders who chose not to work nearly doomed them. By 1621, a year after landing in Massachusetts, they had changed from socialism to a system where each family owned their land and worked it for their family.

read more

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How QbD Can Drive Innovation And Quality In Pharmaceuticals

Science 2.0 - Nov 26 2024 - 18:11

Quality by Design (QbD) is  a decade-long approach that was first introduced by quality expert Joseph M. Juran. Juran proposed a “Juran Trilogy”, of which quality and innovation were two of the pillars necessary to ensure breakthroughs in developing new products, services and processes. Quite simply, Juran believed and evidence has shown that companies could plan for quality and innovation.

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Categories: Science 2.0

How QbD Can Drive Innovation And Quality In Pharmaceuticals

Science 2.0 - Nov 26 2024 - 18:11

Quality by Design (QbD) is  a decade-long approach that was first introduced by quality expert Joseph M. Juran. Juran proposed a “Juran Trilogy”, of which quality and innovation were two of the pillars necessary to ensure breakthroughs in developing new products, services and processes.

read more

Categories: Science 2.0

K0 Regeneration

Science 2.0 - Nov 26 2024 - 14:11
Last week I got to the part of my course in Subnuclear Physics for Statisticians (yes, there is such a course at the Department of Statistical Sciences in Padova, and I have been giving it since its inception 6 years ago!) where I discuss CP violation in the system of neutral K mesons. In one of the most surprising experiments of modern physics, the group of Cronin and Fitch proved in 1964 that the combination of the two symmetries operations called "charge conjugation" C and "parity inversion" P could in some cases modify the properties of physical systems. 

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Categories: Science 2.0

K0 Regeneration

Science 2.0 - Nov 26 2024 - 14:11
Last week I got to the part of my course in Subnuclear Physics for Statisticians (yes, there is such a course at the Department of Statistical Sciences in Padova, and I have been giving it since its inception 6 years ago!) where I discuss CP violation in the system of neutral K mesons. In one of the most surprising experiments of modern physics, the group of Cronin and Fitch proved in 1964 that the combination of the two symmetries operations called "charge conjugation" C and "parity inversion" P could in some cases modify the properties of physical systems. 

read more

Categories: Science 2.0

Queer Death Studies And Shrimp: Welcome To Humanities Academia

Science 2.0 - Nov 26 2024 - 12:11
The abstract for a new humanities paper published by the former Nazis who now own a surprising chunk of science media (Holtzbrinck Publishing Group) reads like it was created using a postmodernism generator.

Maybe it was. It's hard to imagine a human with any critical thinking let this go by, much less the dreaded Reviewer #2, but a pay-to-publish journal like this Journal of Agricultural and Environmental Ethics is really just "editorial review" - the credit card has to clear and then it gets the same level of scrutiny as a paper about astrology gets in an astrology magazine.


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Categories: Science 2.0

Queer Death Studies And Shrimp: Welcome To Humanities Academia

Science 2.0 - Nov 26 2024 - 12:11
The abstract for a new humanities paper published by the former Nazis who now own a surprising chunk of science media (Holtzbrinck Publishing Group) reads like it was created using a postmodernism generator.

Maybe it was. It's hard to imagine a human with any critical thinking let this go by, much less the dreaded Reviewer #2, but a pay-to-publish journal like this Journal of Agricultural and Environmental Ethics is really just "editorial review" - the credit card has to clear and then it gets the same level of scrutiny as a paper about astrology gets in an astrology magazine.


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Categories: Science 2.0

Fake Cheese, Now With More Climate Justice

Science 2.0 - Nov 26 2024 - 09:11
A brand of fake cheese - it must be that Europe doesn't require standards of identity so bacon can label itself vegan if cheese can - is making the rounds on social media again because of its virtue signaling to wealthy progressives that they are saving the planet even more ethically.

By posting their virtual carbon cost. 




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Categories: Science 2.0