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According to a new study, testosterone therapy may reduce non-alcoholic fatty liver disease in obese
Testosterone therapy may help obese men with functional hypogonadism and type-2 diabetes reduce the prevalence of non-alcoholic fatty liver disease (NAFLD), according to a study being presented at the 23rd?European Congress of Endocrinology (e-ECE 2021), on Tuesday 25 May 2021 at 14:00 CET (www.ece2021.org). The two-year study found that therapy with testosterone undecanoate normalised testosterone levels, reduced NAFLD, and suppressed the symptoms of hypogonadism in men living with these conditions.
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Nonprofits, federal government surpass pharma to lead Alzheimer's drug development
Two articles published online today by Alzheimer's & Dementia: Translational Research & Clinical Interventions, a journal of the Alzheimer's Association, show substantial changes in the focus and funding of clinical trials for Alzheimer's disease therapies.
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Soft X-ray method promises nanocarrier breakthroughs for smart medicine
A new technique using chemically-sensitive "soft" X-rays offers a simpler, non-disruptive way of gaining insight into nanocarriers. Currently researchers have to rely on attaching fluorescent dyes or heavy metals to label parts of organic nanocarrier structures for investigation, often changing them in the process. Researchers have demonstrated the capability of the new X-ray method on a smart drug delivery nanoparticle and a polysoap nanostructure intended to capture crude oil spilled in the ocean.
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Odd angles make for strong spin-spin coupling
A Rice University-led study finds a unique form of tunable and ultrastrong spin-spin interactions in orthoferrites under a strong magnetic field. The discovery has implications for quantum simulation and sensing.
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Engineering matter at the atomic level
In a breakthrough that will contribute to this, published in Nature Communications, researchers from the RIKEN Cluster for Pioneering Research and RIKEN Center for Advanced Photonics, along with collaborators, have developed a way to use a "dry transfer technique"--a technique that uses no solvent--to position optical quality carbon nanotubes in a precise way.
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Press (re)play to remember - How the brain strengthens memories during sleep
While we sleep, the brain produces particular activation patterns. When two of these patterns - slow oscillations and sleep spindles - gear into each other, previous experiences are reactivated. The stronger the reactivation, the clearer will be our recall of past events, a new study reveals.
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Harnessing next generation sequencing to detect SARS-CoV-2
Researchers at the Vienna BioCenter designed a testing protocol for SARS-CoV-2 that can process tens of thousands of samples in less than 48 hours. The method, called SARSeq, is published in the journal Nature Communications and could be adapted to many more pathogens.
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"Scuba-diving" lizards use bubble attached to snout to breathe underwater
A team of evolutionary biologists including faculty at Binghamton University, State University of New York have shown that some Anolis lizards, or anoles, have adapted to rebreathe exhaled air underwater using a bubble clinging to their snouts.
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Delivering "serendipity": Seemingly random product discovery, aided by technology
Marketers can capitalize on the power of serendipity to increase consumer satisfaction.
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UBCO researchers examine how pandemics impact the homeless
A team of UBC Okanagan researchers is looking at strategies that could help the homeless during a pandemic. John Graham, director of UBC Okanagan's School of Social Work, says while many populations have been targeted with guidelines to keep them safe, homeless people have been mostly overlooked.
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Mothers' depression impacts mother-infant relationships
Research led by King's College London has found that women with depression during pregnancy, or with a history of depression, had a reduced quality of mother-infant interaction at both eight weeks and 12 months after their babies were born.
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Whale carcasses help answer mysteries of elusive species
A new study published by the open access publisher Frontiers shows the usefulness of opportunistically collected specimens, such as stranded carcasses, to study elusive species. The researchers used stable isotope analysis of skin, muscle, and bone tissue of Sowerby's beaked whales to study their spatial ecology. They found that the species exhibits both short- and long-term habitat fidelity. The results are published in Frontiers in Conservation Science and show the importance of such studies for marine wildlife conservation.
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ED visits for appendicitis, miscarriage fell sharply in first wave of COVID-19 pandemic
Emergency department visits for common conditions such as appendicitis, miscarriage, gallbladder attacks and ectopic pregnancy decreased markedly at the start of the COVID-19 pandemic, but patient outcomes were not worse, found research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.202821.
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Ancient fish bones reveal non-kosher diet of ancient Judeans, say researchers
Ancient Judeans commonly ate non-kosher fish surrounding the time that such food was prohibited in the Bible, suggests a study published in the peer-reviewed journal Tel Aviv.This finding sheds new light on the origin of Old Testament dietary laws that are still observed by many Jews today. Among these rules is a ban on eating any species of fish which lacks scales or fins.
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Mapping the local cosmic web
A new map of dark matter in the local universe reveals several previously undiscovered filamentary structures connecting galaxies. The map, developed using machine learning, could enable studies about the nature of dark matter as well as about the history and future of our local universe.
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Antibodies that enhance SARS-CoV-2 infection -- A possible factor for severe COVID-19
Osaka University researchers found that infection with SARS-CoV-2 produces not only neutralizing antibodies that prevent infection, but also infection-enhancing antibodies. They demonstrated that the infection-enhancing antibodies enhance the infectivity of SARS-CoV-2 by modulating the conformation of spike protein of SARS-CoV-2. Furthermore, the infection-enhancing antibodies attenuated the ability of neutralizing antibodies to prevent infection. Their findings will help to develop vaccines that do not induce the production of infection-enhancing antibodies.
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Intermittent fasting in mice effective at promoting long term memory retention
Intermittent Fasting (IF) is an effective means of improving long term memory retention and generating new adult hippocampal neurons in mice. Researchers hope that this has the potential to slow the advance of cognitive decline in older people.
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COVID-19 infections were high among hospital staff but re-infection rates are very low
A study of healthcare workers shows they were three times more likely to become infected during the COVID-19 pandemic compared to the general population. However, health care workers who had been infected were very unlikely to contract COVID-19 a second time in the following six months.
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RMRS scientists recommend approach to adapt to uncertainty in wildland management
Scientists from the Rocky Mountain Research Station collaborated to explore how research and management can confront increasing uncertainty due to climate change, invasive species, and land use conversion. In new research published in Frontiers in Forests and Global Change, the authors recommend a more inclusive and collaborative governance model that would increase public and stakeholder participation, integrate research and management, and incorporate multiple forms of knowledge, including from indigenous communities.
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Columbia Engineering team builds first hacker-resistant cloud software system
Columbia Engineering researchers have developed SeKVM, the first system that guarantees--through a mathematical proof--the security of virtual machines in the cloud. "This is the first time that a real-world multiprocessor software system has been shown to be mathematically correct and secure," said Computer Science Professor Jason Nieh. "This means that users' data are correctly managed by software running in the cloud and are safe from security bugs and hackers."
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