The best of AGA science at DDW® 2016

San Diego, CA (May 16, 2015) -- The gastroenterology and hepatology community will gather in San Diego May 21 through 24, 2016, for Digestive Disease Week® (DDW)http://www.ddw.org to hear cutting-edge science and presentations from leading experts in the field. For media attending DDW 2016, use this guide to find AGA's highlighted abstracts at the meeting. We've also outlined sessions on the gut microbiome, an exciting area of medical research where AGA has expanded its focus over the past several years.

All data presented during DDW is embargoed until the beginning of the presentation or an official DDW press conference, whichever occurs first. For information on DDW press activities, visit http://www.ddw.org/press.

All sessions will be held in the San Diego Convention Center (Pacific Time). For more information on presentations and data being presented, visit http://www.myddw.org.

Presidential Plenary

Hear from AGA Institute President Michael Camilleri, MD, AGAF, during the 2016 AGA Presidential Plenary, on Monday, May 23, 2016, 8 to 11:30 a.m. in Room 20BCD. Mixed in with high-level presentations on the topics of obesity management, hollow organ failure and upper GI cancers, the following seven abstracts will be highlighted:

  • Abstract 594: Final Results of Multi-Center, Prospective, Controlled Trial of the Duodeno-Jejunal Bypass Liner for the Treatment of Type 2 Diabetes Mellitus in Obese Patients: Efficacy and Factors Predicting a Suboptimal Effect; Marek Benes
  • Abstract 595: Post-Colonoscopy Colorectal Cancer Rates Have Decreased Over Time in Average-Risk Patients Aged 50 to 74: A Population-Based Study from Ontario, Canada; Sanjay Murthy
  • Abstract 596: Detection of Pancreatic High-Grade Dysplasia and Cancer using Novel Methylated DNA Markers: Discovery and Tissue Validation; Shounak Majumder
  • Abstract 597: Molecular Markers Help Define Cyst Type in the Pancreas: An International, Multicenter Study of Over 300 Cysts; Anne Marie Lennon
  • Abstract 598: Efficacy and Safety of Naldemedine for the Treatment of Opioid-Induced Constipation in Subjects With Chronic Non-Cancer Pain Receiving Opioid Therapy: Results From Two Phase 3 Clinical Trials; Martin Hale
  • Abstract 599: The Monoclonal Antibody, Bezlotoxumab Targeting C. Difficile Toxin B Shows Efficacy in Preventing Recurrent C. Difficile Infection (CDI) in Patients at High Risk of Recurrence or of CDI-Related Adverse Outcomes; Ciaran Kelly
  • Abstract 600: Multi Donor Intense Faecal Microbiota Transplantation is an Effective Treatment for Resistant Ulcerative Colitis: A Randomised Placebo-Controlled Trial; Sudarshan Paramsothy

Noteworthy AGA Clinical Abstracts

On Tuesday, May 24, 2016 AGA will highlight the most noteworthy clinical practice data presented at DDW 2016 during the Clinical Practice Distinguished Abstract Plenary, taking place from 8 to 9:30 a.m. in Room 32. Abstracts to be presented include:

  • Abstract 819: Black-White Disparity Trends in Colorectal Cancer Incidence and Stage at Presentation in the United States; Folasade May
  • Abstract 820: Gastrointestinal Safety of Direct Oral Anticoagulants: A Head-to-Head Study; Neena Abraham
  • Abstract 821: A Low FODMAP Diet Improves Quality of Life, Reduces Activity Impairment, and Improves Sleep Quality in Patients With Irritable Bowel Syndrome and Diarrhea: Results From a United States Randomized, Controlled Trial; Shanti Eswaran
  • Abstract 822: Prevalence and Predictors of Irritable Bowel Syndrome in the United States; Christopher Almario
  • Abstract 823: Increased Detection of Celiac Disease and Avoidance of Gluten Without a Diagnosis in the United States; Rok Seon Choung
  • Abstract 824: Project Sonar: Reduction in Cost of Care in an Attributed Cohort of Patients With Crohn's Disease; Lawrence Kosinski

AGA Basic Science Abstracts

Attend the AGA Basic Science Plenary on Sunday, May 22, 2016, from 4 to 5:30 p.m. in Room 25, where the most noteworthy contributions to gastroenterology basic science research will be presented, including:

  • Abstract 431: Protease-Activated Receptor 2 Signals From Endosomes to Control Sensitivity of Nociceptors; Peishen Zhao
  • Abstract 432: ATG16L1 and XBP1 Coordinate Interleukin 22 Dependent Signals in Intestinal Epithelium; Konrad Aden
  • Abstract 433:?Functional Enteric Nervous System in Human Small Intestine Derived From Pluripotent Stem Cells; Maxime Mahe
  • Abstract 434: CD44 Is Required for Regeneration of the Gastric Epithelium in Response to Injury: A Mechanism Lost in the Aging Stomach; Joel Gabre
  • Abstract 435: Microbiota-Dependent Signals Link ATF6-Driven Unfolded Protein Response to Colonic Tumorigenesis; Elena Lobner
  • Abstract 436: Transmissible Protection From Fructose Induced Hepatic Steatosis Using Microbiota From Mice With Defective Intestinal Chylomicron Production; Yan Xie

Microbiome Programming

Through the AGA Center for Gut Microbiome Research and Education http://www.gastro.org/about/initiatives/aga-center-for-gut-microbiome-research-education, AGA is committed to advancing research into the gut microbiome. To that end, there will be several AGA sessions at DDW 2016 focused on this important area of research, including:

  • Gut Bugs and Their Products: The Keys to Inflammatory Drive?, Saturday, May 21, 8-9:30 a.m., Room 29BUnderstanding the Microbial Host Interaction, Saturday, May 21, 2-3:30 p.m., Room 29B
  • Gut Microbiome in Pediatric Gastrointestinal Diseases, Sunday, May 22, 10-11:30 a.m., Room 29A
  • Active Learning Session on the Gut Microbiome: Fundamental Principles in Theory and Practice, Sunday, May 22, 4-5:30 p.m., Room 33

Learn more about AGA's highlighted sessions at DDW 2016.http://www.ddw.org/program/program-highlights-by-society/aga-highlights

Source: American Gastroenterological Association