Tech

Research conducted at the Irvine Lab at the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology is being utilized in Elicio's AMP-CAR-T Platform

Activation of CAR-T cells with Amphiphiles delivered to the lymph nodes induces massive CAR-T expansion, substantially improved efficacy across cancer types, and durable cures for solid tumors

Achieving a milestone in artificial intelligence (AI) by moving beyond settings involving only two players, researchers present an AI that can outperform top human professionals in six-player no-limit Texas hold'em poker, the most popular form of poker played today. This system is the only AI to have bettered professional poker players at this multi-player game. In recent years, researchers have reported great strides in artificial intelligence. Often, games serve as challenge problems, benchmarks, and milestones for this progress.

WASHINGTON -- In the first of a kind study, plastic surgeons at Georgetown University Medical Center found that when a man chose to have a nip or a tuck on his face, it significantly increased perceptions of attractiveness, likeability, social skills, or trustworthiness.

As a cucumber plant grows, it sprouts tightly coiled tendrils that seek out supports in order to pull the plant upward. This ensures the plant receives as much sunlight exposure as possible. Now, researchers at MIT have found a way to imitate this coiling-and-pulling mechanism to produce contracting fibers that could be used as artificial muscles for robots, prosthetic limbs, or other mechanical and biomedical applications.

SAN FRANCISCO (July 11, 2019) - Africa has new purple-clad warriors more than 200 feet beneath the ocean's surface. Deep-diving scientists from the California Academy of Sciences' Hope for Reefs initiative and the University of Sydney spotted dazzling fairy wrasses--previously unknown to science--in the dimly lit mesophotic coral reefs of eastern Zanzibar, off the coast of Tanzania.

An evaluation of the global energy return on investment for fossil fuels and renewable sources reveals a much more level playing field than previously believed.

An enduring argument for the ongoing use of fossil fuels is their high energy return on energy investment. This refers to the ratio of how much energy a source such as coal or oil will produce compared to how much energy it takes to extract.

For a patient, a diagnostic error can mean the difference between life and death. While estimates vary, likely more than 100,000 Americans die or are permanently disabled each year due to medical diagnoses that initially miss conditions or are wrong or delayed.

"All matter consists of positively charged atomic nuclei and negatively charged electrons," explains Professor Dr.-Ing. Rolf Findeisen from the Institute of Automation Technology at the University of Magdeburg. "These generate electrical potentials. Using conventional methods, until now it has been barely possible to measure these very weak fields, which are responsible for many of the characteristics and functionalities of materials."

The German Act on the Reform of the Market for Medicinal Products (AMNOG) was introduced in 2011 to regulate the early benefit assessment of new drugs. More than half of the drugs that have entered the market in Germany since then have emerged from these assessments without any proven added benefit. In a publication in the British Medical Journal using the first 216 assessments, researchers from the Institute for Quality and Efficiency in Health Care (IQWiG) examine the reasons for this sobering result and develop suggestions for improvements in drug development.

The idea of genetically modifying a patient's own immune cells and deploying them against infections and tumors has been around since the 1980s. But to this day modified T cells are still not as effective as natural T cells and have been only been of limited clinical value. Using the new CRISPR-Cas9 gene editing tool, a team at the Technical University of Munich (TUM) has now engineered T cells that are very similar to physiological immune cells.

The acidification of the oceans is recorded in the crystals of the coral skeleton. This is a new tool for studying past environmental changes and combating climate change. Such is the main conclusion of a study led by the Spanish scientist Ismael Coronado Vila, from the Institute of Paleobiology in Warsaw (Poland).

Since light-emitting diodes only produce monochrome light, manufacturers use various additive colour-mixing processes to produce white light.

A synthetic approach developed by KAUST researchers generates homogeneous and defect-free crystals that could fast-track the commercialization of perovskite solar cells.

"Perovskite solar cells are the fastest developing type of photovoltaic technology, with power-conversion efficiencies rising from 3.8 percent in 2009 to 24.2 percent in 2019 for single-junction devices," says Osman Bakr, who led the study with Omar Mohammed. This rapid increase in performance is associated with inexpensive and simple device fabrication, which makes these solar cells commercially appealing.

ANN ARBOR--An injection of nanoparticles can prevent the body's immune system from overreacting to trauma, potentially preventing some spinal cord injuries from resulting in paralysis.

The approach was demonstrated in mice at the University of Michigan, with the nanoparticles enhancing healing by reprogramming the aggressive immune cells--call it an "EpiPen" for trauma to the central nervous system, which includes the brain and spinal cord.

Researchers from the National University of Science and Technology "MISIS" developed a database that will help create new grades of steels. This will speed up the process of creating innovative steel grades with specified strength and ductility allow at least 10 times, which will allow manufacturing car bodies of the most complex shapes. Article on the research is published in "Calphad".