Tech

A small molecule that inhibits energy production in immune T-cells allows some tumours to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

For people living with HIV, any level of alcohol consumption is associated with lower levels of a protein involved in bone formation, raising the risk of osteoporosis, according to a new study by researchers from the Boston University School of Public Health (BUSPH) and School of Medicine (BUSM) and published in the journal Alcoholism: Clinical and Experimental Research.

Most people know that good oral hygiene - brushing, flossing, and regular dental visits - is linked to good health. Colorado State University microbiome researchers offer fresh evidence to support that conventional wisdom, by taking a close look at invisible communities of microbes that live in every mouth.

With a small zap of electricity, biomedical engineers at Michigan Technological University take an underwater smart glue prototype from sticky to not in seven seconds.

A smartphone app that allows users to check for jaundice in newborn babies simply by taking a picture of the eye may be an effective, low-cost way to screen for the condition, according to a pilot study led by UCL and UCLH.

Jaundice, where the skin and whites of the eyes turn yellow, causes 114,000 newborn deaths and 178,000 cases of disability a year worldwide, despite being a treatable condition. Three quarters of deaths are in south Asia and sub-Saharan Africa.

TROY, N.Y. -- From cell phones, to solar power, to electric cars, humanity is increasingly dependent on batteries. As demand for safe, efficient, and powerful energy storage continues to rise, so too does the call for promising alternatives to rechargeable lithium-ion batteries, which have been the dominant technology in this space.

Across the globe, humans are using freshwater resources faster than those resources can be naturally replenished. In the Western United States, for example, water extractions from the Colorado River have exceeded total river flow, causing rapid depletion of water storage reservoirs. In addition, as these water sources dry up, species of fish, plants and animals are also adversely impacted.

New Rochelle, NY, March 2, 2020--A new Commentary identifies three actionable challenges for translating pharmacomicrobiomics to personalized medicine in 2020. Pharmacomicrobiomics is the study of how microbiome variations within and between individuals affect drug action, efficacy, and toxicity. This personalized medicine horizon scanning is featured in OMICS: A Journal of Integrative Biology, the peer-reviewed interdisciplinary journal published by Mary Ann Liebert, Inc., publishers.

HOUSTON - (March 2, 2020) - Now there's evidence that oil and water do mix. Sort of.

Scientists at Rice University's Brown School of Engineering show that microscopic saltwater droplets emulsify crude oil when each has the right composition. Understanding how they combine is important to enhanced oil recovery.

Rice chemical and biological engineer Sibani Lisa Biswal and her colleagues went to great lengths to characterize the three elements most important to oil recovery: rock, water and the crude itself.

Pollination by bees is vital even when crops are assumed to be pollinator independent. That's according to a study co-authored by Ethel Villalobos, a researcher in the University of Hawaii at Manoa's College of Tropical Agriculture and Human Resources Department of Plant and Environmental Protection Sciences and lead of the UH Honeybee Project.

PITTSBURGH, March 2, 2020 - Frail patients in private-sector, multi-hospital health systems may benefit from a tool that can quickly predict their risk for poor outcomes following surgery, including postoperative mortality, readmission and extended hospital stays.

CHAMPAIGN, Ill. -- Novel biomedical advances that show promise in the lab often fall short in clinical trials. For researchers studying peripheral artery disease, this is made more difficult by a lack of standardized metrics for what recovery looks like. A new study from University of Illinois at Urbana-Champaign researchers identifies major landmarks of PAD recovery, creating signposts for researchers seeking to understand the disease and develop treatments.

Plexin-B2, an axon guidance protein in the central nervous system (CNS), plays an important role in wound healing and neural repair following spinal cord injury (SCI), according to research conducted at the Icahn School of Medicine at Mount Sinai and published today in Nature Neuroscience. The study's findings could aid the development of therapies that target axon guidance pathways for more effective treatment of SCI patients.

U.S. states with laws regulating the storage of firearms in households with minors had a 13 percent reduction in firearm fatalities in children under 15 compared to states with no such regulations, finds a study from Boston Children's Hospital. States with the most restrictive laws had the greatest reduction: 59 percent reduction as compared to states with no laws. Results of this analysis, spanning 26 years, were published in a paper on March 2, 2020 in JAMA Pediatrics.

A technique based on the principles of MRI has allowed researchers to observe not only how next-generation batteries for large-scale energy storage work, but also how they fail, which will assist in the development of strategies to extend battery lifetimes in support of the transition to a zero-carbon future.