Tech

A new study reveals a possible biological reason that Alzheimer's Disease (AD) progresses at different rates in different patients.

The study, which was led by Massachusetts General Hospital researchers, focused on tau, a protein found in the neurofibrillary tangles in the brain that are a well-known sign of AD.

Tau can undergo a variety of modifications during the course of the disease including phosphorylations. Researchers found that the presence of different forms of phosphorylated tau could explain why the disease has variable effects.

ITHACA, N.Y. - New research by Cornell University and the City College of New York (CCNY), shows that by enforcing a $20 toll for cars and taxis to enter the central business district of Manhattan, traffic congestion could be reduced by up to 40%, public transit ridership could grow by 6% and greenhouse gas emissions could be reduced by 15%.

MISSOULA - Melting of Arctic ice due to climate change has exposed more sea surface to an atmosphere with higher concentrations of carbon dioxide. Scientists have long suspected this trend would raise CO2 in Arctic Ocean water.

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism. While medications are used to treat some of the manifestations of the disease, safe and more effective treatments targeting disease at a fundamental level are lacking.

UNIVERSITY PARK, Pa. -- Conservation efforts that open up the canopy of overgrown habitat for threatened timber rattlesnakes--whose venom is used in anticoagulants and other medical treatments--are beneficial to snakes but could come at a cost, according to a new study by researchers at Penn State and the University of Scranton. The researchers confirmed that breeding areas with more open canopies do provide more opportunities for these snakes to reach required body temperatures, but also have riskier predators like hawks and bobcats.

One way that scientists seek to bring to Earth the fusion process that powers the sun and stars is trapping hot, charged plasma gas within a twisting magnetic coil device shaped like a breakfast cruller. But the device, called a stellarator, must be precisely engineered to prevent heat from escaping the plasma core where it stokes the fusion reactions. Now, researchers at the U.S. Department of Energy's (DOE) Princeton Plasma Physics Laboratory (PPPL) have demonstrated that an advanced computer code could help design stellarators that confine the essential heat more effectively.

A new machine learning algorithm allows researchers to explore possible designs for the microstructure of fuel cells and lithium-ion batteries, before running 3D simulations that help researchers make changes to improve performance.

Improvements could include making smartphones charge faster, increasing the time between charges for electric vehicles, and increasing the power of hydrogen fuel cells running data centres.

The paper is published today in npj Computational Materials.

Under changing, increasingly dynamic climatic conditions, temperate soils are forecast to experience a high degree of variability in moisture conditions due to periods of drought and/or flood. These periodic shifts between well-drained and waterlogged conditions have the potential to enhance carbon cycling by microbes and influence soil quality and land-derived greenhouse gas emissions.

An international team of researchers, affiliated with UNIST has unveiled a novel material that could enable major leaps in the miniaturization of electronic devices. Published in the prestigious journal Nature, this study represent a significant achievement for future electronics.

Facebook is a more fertile breeding ground for fake news than Twitter, and those on the far ends of the liberal-conservative spectrum are most likely to share it, according to new CU Boulder research.

The paper, in the journal Human Communication Research, also found that people who lack trust in conventional media, and in one another, post misinformation more often.

One-click purchases and instant delivery have helped fuel the growth of e-commerce, but this convenience has come at the cost of increased traffic congestion, longer commute times, and strained urban communities. A 2018 report from Texas A&M University found that delivery trucks represent just 7% of U.S. traffic but account for 28% of the nation's congestion. Delivery drones could help take some of the load off the pavement, and aerial delivery systems already operate in some countries. But even the best drones have limited payload capacity and flight range.

Xiang-Dong Fu, PhD, has never been more excited about something in his entire career. He has long studied the basic biology of RNA, a genetic cousin of DNA, and the proteins that bind it. But a single discovery has launched Fu into a completely new field: neuroscience.

UC researchers have found a potential new combination therapy for breast cancer that would integrate use of the body's immune system with targeted treatment for a particular protein that advances cancer.

What The Viewpoint Says: The use of online platforms to guide effective consumption of information, facilitate social support and continue mental health care delivery during the COVID-19 pandemic is discussed in this Viewpoint.

Authors: Yuval Neria, Ph.D., of the Columbia University Irving Medical Center in New York, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamapsychiatry.2020.1730)

Scientists from the German Cancer Research Center and the Universities of Cambridge and Edinburgh have been studying the evolution of tumors following chemical damage. They discovered that the DNA lesions caused by the chemical are not eliminated immediately, but are passed on unrepaired over several rounds of cell division. Both DNA strands with their independent sets of lesions are separated during cell division, resulting in two daughter cells with different patterns of DNA changes - their mutation profiles.