A cytomegalovirus (CMV)-based vaccine provides long-lasting protective immunity against Ebola virus, and has potential for development as a disseminating vaccine strategy to prevent ebolavirus infection of wild African ape populations.
A new study shows the durability of a novel 'disseminating' cytomegalovirus (CMV)-based Ebola virus (Zaire ebolavirus; EBOV) vaccine strategy that may eventually have the potential to reduce ebolavirus infection in wild African ape species.
For people taking glucocorticoids such as prednisone, the increased risk of bone fracture is a well-documented side effect. Used to treat a variety of medical conditions, including autoimmune diseases and allergies, glucocorticoids are known to cause rapid deterioration in bone strength.
A new study finds that it is possible to detect endometrial cancer using tumor DNA picked up by ordinary tampons. DNA samples from vaginal secretions can show the presence of chemical "off" switches - known as methylation - that can disable genes that normally keep cancer in check.
The finding is a critical step toward a convenient and effective screening test for endometrial cancer, which is the most common gynecologic malignancy in the United States.
Milk is a key element for household food security and provides a stable income to farmers including women, who are usually in charge of taking care of the milk-producing animals in the low-income countries. Currently pathogen growth in milk is managed with refrigeration or with chemicals.
Although bacterial growth in milk is managed with refrigeration in the high-income countries, a high cost of infrastructure and a demand for a permanent electricity supply prevent milk refrigeration in the rural areas in the low-income countries.
Recycling plastic works, additives to biodegrade plastic do not, according to a new study from Michigan State University which finds that several additives that claim to break down polyethylene (i.e., plastic bags) and polyethylene terephthalate (i.e., soda bottles) simply don't work in common disposal situations such as landfills or composting.
"Making improper or unsubstantiated claims can produce consumer backlash, fill the environment with unwanted polymer debris and expose companies to legal penalties," said Susan Selke, co-author of the study and MSU packaging professor.
The first blood test for osteoarthritis could soon be developed, thanks to research by the University of Warwick.
The research findings could potentially lead to patients being tested for osteoarthritis and diagnosed several years before the onset of physical symptoms.
Conducted by the University's Medical School, the research identified a biomarker linked to both rheumatoid and osteoarthritis.
Sipuleucel-T (trade name Provenge) has been approved since September 2014 for men with metastatic prostate cancer who have few or no symptoms and do not yet require chemotherapy. In the dossier assessment conducted by the German Institute for Quality and Efficiency in Health Care (IQWiG) in January 2015, no added benefit could be derived for sipuleucel-T.
If every new car made in the United States had a built-in blood alcohol level tester that prevented impaired drivers from driving the vehicle, how many lives could be saved, injuries prevented, and injury-related dollars used for something else?
To combat global climate change caused by greenhouse gases, alternative energy sources and other types of environmental recourse actions are needed. There are a variety of proposals that involve using vertical ocean pipes to move seawater to the surface from the depths in order to reap different potential climate benefits. A new study from a group of Carnegie scientists determines that these types of pipes could actually increase global warming quite drastically. It is published in Environmental Research Letters.
If kidney cancer is diagnosed early -- before it spreads -- 80 percent of patients survive. However, finding it early has been among the disease's greatest challenges.
Now, researchers at Washington University School of Medicine in St. Louis have developed a noninvasive method to screen for kidney cancer that involves measuring the presence of proteins in the urine.
The findings are reported March 19 in the journal JAMA Oncology.
A new study adds fuel to the already hot debate about whether electric vehicles are more environmentally friendly than conventional vehicles by uncovering two hidden benefits.
They show that the cool factor is real - in that electric vehicles emit significantly less heat. That difference could mitigate the urban heat island effect, the phenomenon that helps turn big cities like Beijing into pressure cookers in warm months.
When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients' health can deteriorate rapidly. New research published in the American Journal of Transplantation indicates that emergency evaluations of living liver donors can be conducted safely to allow acute liver failure patients to undergo transplantation before their condition worsens.
A phase 3 trial of brentuximab vedotin (BV), the first new drug for Hodgkin lymphoma in over 30 years, shows that adults with hard-to-treat Hodgkin lymphoma given BV immediately after stem cell transplant survived without the disease progressing for twice as long as those given placebo (43 months vs 24 months).
The findings, published in The Lancet, are potentially practice changing for this young cancer population who have exhausted other treatment options and for whom prognosis is poor.
Using discarded electronic boards, the UPV/EHU researcher Andoni Salbidegoitia has, in collaboration with international researchers, developed a system for obtaining clean hydrogen that can be used as fuel. The researchers have already registered the patent of the process in Japan.
The Chemical Technologies for Environmental Sustainability (TQSA) Group of the Department of Chemical Engineering of the UPV/EHU's Faculty of Science and Technology is aiming to make use of discarded plastic as effectively as possible from the environmental as well as energy and economic point of view.
Without antibodies we would be at the mercy of pathogens or cancer cells. Therapeutic antibodies are used as passive vaccines, for cancer therapy or for controlling autoimmune diseases such as multiple sclerosis. According to "bccresearch.com" the global market for antibody drugs was worth nearly 70 billion USD in 2014 and should rise to 122 billion USD until 2019.