The UK's self-regulatory approach to preventing pharmaceutical companies from promoting off-label use of their drugs detects mainly high-visibility promotional activity such as print advertising, according to a document analysis of off-label promotion rulings published this week in PLOS Medicine by Shai Mulinari and colleagues at Lund University, Sweden, and King's College London, UK. The study indicates that the UK self-regulatory approach is less capable of uncovering complex marketing campaigns than the government-led approach in the US.
Tech
People who have used Bitcoin, and those who don't have any experience with it, have something in common: Both groups share misconceptions about how the controversial digital currency actually works.
WHAT:Oral immunotherapy for peanut allergy induces early, distinct changes in immune T-cell populations that potentially may help researchers determine which people will respond well to the therapy and which immune mechanisms are involved in the response, a new study suggests. The work was funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and conducted by scientists at Stanford University.
TALLAHASSEE, Fla. -- A Florida State University researcher and his team have developed a comprehensive analysis of oil in the Gulf of Mexico and determined how much of it occurs naturally and how much came from the 2010 Deepwater Horizon spill.
And more importantly, their data creates a map, showing where the active natural oil seeps are located.
The research was recently released online by the Journal of Geophysical Research Oceans and is also the basis for a paper with researchers at Columbia University published today in Nature Geoscience.
(CAMBRIDGE, Massachusetts) - Researchers in the field of mechanobiology are evolving our understanding of health by revealing new insights into how the body's physical forces and mechanics impact development, physiological health, and prevention and treatment of disease. At the Wyss Institute for Biologically Inspired Engineering at Harvard University, engineers and biomedical scientists have assembled to form collaborative teams that are helping to drive this exciting area of research forward toward real-world applications.
When an automobile's engine is improperly lubricated, it can be a major hit to the pocketbook and the environment.
For the average car, 15 percent of the fuel consumption is spent overcoming friction in the engine and transmission. When friction is high, gears have to work harder to move. This means the car burns more fuel and emits more carbon dioxide into the atmosphere.
BUFFALO, N.Y. - Like Beanie Babies and Steve Urkel, the systems we use to transmit information through water bring to mind the 1990s.
The flashback is due to the speed of today's underwater communication networks, which is comparable to the sluggish dial-up modems from America Online's heyday. The shortcoming hampers search-and-rescue operations, tsunami detection and other work.
But that is changing due in part to University at Buffalo engineers who are developing hardware and software tools to help underwater telecommunication catch up to its over-the-air counterpart.
In the water above natural oil seeps in the Gulf of Mexico, where oil and gas bubbles rise almost a mile to break at the surface, scientists have discovered something unusual: phytoplankton, tiny microbes at the base of the marine food chain, are thriving.
The United States could slash greenhouse gas emissions from power production by up to 78 percent below 1990 levels within 15 years while meeting increased demand, according to a new study by NOAA and University of Colorado Boulder researchers.
The study used a sophisticated mathematical model to evaluate future cost, demand, generation and transmission scenarios. It found that with improvements in transmission infrastructure, weather-driven renewable resources could supply most of the nation's electricity at costs similar to today's.
"Humidity is one of the most controlled and most monitored aspects nowadays owing to its great importance in a whole range of industrial processes or in areas such as food monitoring, air quality, biomedicine or chemistry," explained Aitor Urrutia, who is from Auritz/Burguete, but who currently resides in Irúñea-Pamplona. "Yet problems remain in terms of measuring and monitoring it in specific situations such as environments where the humidity level is very high".
Lincoln, Neb., Jan. 22, 2016 -- A 200-square-foot slab of seemingly ordinary concrete sits just outside the Peter Kiewit Institute as snowflakes begin parachuting toward Omaha on a frigid afternoon in late December.
The snow accumulates on the grass surrounding the slab and initially clings to the concrete, too. But as the minutes pass and the snow begins melting from only its surface, the slab reveals its secret: Like razors, stoves and guitars before it, this concrete has gone electric.
Fukuoka, Japan - Carbon capture and storage projects rely on effective monitoring of injected CO2. However, the high number of necessary surveys makes this a costly endeavor.
Researchers from North Carolina State University have demonstrated the transfer of triplet exciton energy from semiconductor nanocrystals to surface-bound molecular acceptors, extending the lifetime of the originally prepared excited state by six orders of magnitude. This finding has implications for fields ranging from solar energy conversion to photochemical synthesis to optoelectronics to light therapy for cancer treatment.
Too much confidence is placed in economic games, according to research by academics at Oxford University.
While traditional economic and evolutionary theory predicts that people will typically seek to maximise their own success, the results of economic games have shown people to be much more altruistic than expected.
A limitation of organ transplant is acute rejection of the graft by the host immune system. Graft rejection is mediated by the development of CD8+ cytotoxic T cells that target donor MHC class I molecules, and in animal models, these cells have been shown to develop in secondary lymphoid organs. However, in humans, there is evidence that cytotoxic T cells mature within the graft without trafficking to secondary sites. A new study in the inaugural issue of JCI Insight indicates that the development of graft-targeting CD8+ cytotoxic T cells requires CD4+ effector memory T cells.