Tech

WEST LAFAYETTE, Ind. -- Autonomous underwater vehicles have become versatile tools for exploring the seas. But they can be disruptive to the environment or have trouble traveling through confined spaces.

Purdue University researchers are studying an alternative: highly maneuverable, low-cost underwater gliders that operate silently. Components and sensors of the glider also can be easily swapped out or added according to a wide range of mission specifications.

Redirection of lymphocytes, via T-cell bispecific antibodies (TCBs) and chimeric antigen receptors (CARs), is already approved to treat some hematologic malignancies. In solid tumors these immune-based strategies continue to fail.

In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. The findings suggest endocrine-targeted therapies and an assessment of biomarkers in hormone and insulin signaling pathways may be useful in the prevention and treatment of endometrial cancer recurrence. The study is a collaboration with researchers at the University of Hawaii and The International Agency for Research on Cancer (IARC) and is published online today in the journal Cancer Epidemiology Biomarkers and Prevention.

With a survival rate of only five years, the most common and aggressive form of primary brain tumor, glioblastoma multiforme, is notoriously hard to treat using current regimens that rely on surgery, radiation, chemotherapy and their combinations.

Using the symmetries of the systems, people can define various topological invariants to describe different topological states. The topological materials can be accurately discovered by calculating the topological invariants.

A new research study out of the University of Nevada, Reno's School of Community Health Sciences has just been published by the American Journal of Public Health and addresses state preemption of local sugar-sweetened beverage (SSB) taxes, issuing an emerging public health threat. Assistant Professor Eric Crosbie examines commercial determinants of health and public health policy, specifically in industries like tobacco and food and beverage.

Isn't it convenient when office building windows adaptively darken according to the intensity of sunlight? Or when standard glasses turn into sunglasses under the sun and switch back as you enter a building? Such feats are possible thanks to photochromic materials, whose optical (and other) properties change radically when irradiated by visible or ultraviolet light.

URBANA, Ill. ¬- In today's global economy, production of goods depends on inputs from many trade partners around the world. Companies and governments need a deeper understanding of the global value chain to reduce costs, maintain a profitable production system, and anticipate ripple effects of disruptions in the supply chain.

The development of low-energy-consumption and user-friendly electronic displays has become a long-term goal for future global sustainable development. Bistable electronic display, which requires very little electric drive to turn pages without consuming additional power to continuously display information/images, is one of the very good potential alternatives. Reflective display technologies with partial/complete bistable characteristics include e-ink, cholesteric liquid crystal, and electrochromic technologies, etc.

The yellow fever mosquito (Aedes aegypti) is a main vector of deadly diseases like dengue fever, chikungunya, and the Zika virus, which result in hundreds of thousands of deaths worldwide each year. Because Ae. aegypti prefers to bite humans and there are no vaccines for many of these diseases they carry, developing methods to control these insects is imperative in the fight to control illness.

Integrated photonics was rejuvenated as Si starting challenging the dominant position of conventional III-V compound semiconductors at onset of the new millennium. Heterogeneous Si photonics utilizes wafer bonding to transfer functioning non-Si thin film onto Si substrate to make up missing or weak optoelectronic functionalities of Si material. In the past 15 years, it has evolved into a broad technology with many branches as shown in Fig. 1.

As part of the Journal of Experimental Biology's Special Issue dedicated to climate change, Anthony Pagano (San Diego Zoo Global, USA) and Terrie Williams (University of California, Santa Cruz, USA), discuss the impact of environmental change on two iconic polar species; the polar bear and narwhal. Their review article is published in Journal of Experimental Biology at https://jeb.biologists.org/content/224/Suppl_1.

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren't completely successful. Now, researchers reporting in ACS' Nano Letters have developed magnesium-based micromotors propelled by hydrogen bubbles, which improved rheumatoid arthritis symptoms when injected into the joints of rats.

PHILADELPHIA - A machine learning-based tool was able to predict the risk of malignancy among patients presenting with multiple pulmonary nodules and outperformed human experts, previously validated mathematical models, and a previously established artificial intelligence tool, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

In the largest genome-wide association study of glaucoma comparing the genes of 34,179 people with the disease to 349,321 control subjects, an international consortium of researchers identified 44 new gene loci and confirmed 83 previously reported loci linked to glaucoma. Loci are considered "genetic street addresses," denoting a specific location on a gene.

The study's authors hope the identification of these genes will lead to new treatment targets for this incurable eye disease that is a leading cause of blindness worldwide.