Culture

Cheaper anti-cancer drug as effective as expensive drug in treating wet AMD

An anti-cancer drug has been proven to be equally as effective in treating the most common cause of blindness in older adults as a more expensive drug specifically formulated for this purpose.

The results of a two-year trial, led by Queen's scientist Professor Usha Chakravarthy, and published in The Lancet today (Friday 19 July), show that two drug treatments Lucentis and Avastin are equally effective in treating neovascular or wet age-related macular degeneration (wet AMD).

Childhood abuse raises drug users' suicide risk

PROVIDENCE, R.I. [Brown University] — For health professionals, the message from a new study in the American Journal of Public Health is clear: Asking patients about a history of childhood abuse can directly help assess their risk of attempting suicide. The evidence, authors say, shows that childhood abuse can have life-and-death consequences for the rest of a person's life.

Recommended calorie information on menus does not improve consumer choices, Carnegie Mellon study shows

PITTSBURGH—Despite the lack of any concrete evidence that menu labels encourage consumers to make healthier food choices, they have become a popular tool for policymakers in the fight against obesity.

Obesity and asthma: Study finds a link in the genes

BUFFALO, N.Y. — Genes linked to chronic inflammation in asthma may be more active in people who are obese, according to new research that uncovers several biological ties between obesity and asthma.

"Our findings point the way to the management of asthma in the obese through simple weight reduction," said first author Paresh Dandona, MD, PhD, SUNY Distinguished Professor and Chief of Endocrinology, Diabetes and Metabolism at the University at Buffalo.

New treatment offers hope for short-bowel syndrome patients

Bethesda, MD (July 18, 2013) — A new drug, teduglutide, offers significant relief for patients with short-bowel syndrome intestinal failure who are reliant on intravenous nutrition, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Patients with this relatively rare condition experience massive bowel loss and are unable to absorb nutrients, vitamins and water from digested foods. They rely on parenteral nutrition, or intravenous feeding, to deliver their daily nutrients.

Evolutionary changes could aid fisheries

Evolutionary changes induced by fisheries may benefit the fishers, according to a new study published last week in the Proceedings of the National Academy of Sciences. But if fisheries are not well-managed, this potential benefit turns into economic losses, as stocks decline from overfishing and further suffer from evolution.

Biochemical mapping helps explain who will respond to antidepressants

DURHAM, N.C. -- Duke Medicine researchers have identified biochemical changes in people taking antidepressants – but only in those whose depression improves. These changes occur in a neurotransmitter pathway that is connected to the pineal gland, the part of the endocrine system that controls the sleep cycle, suggesting an added link between sleep, depression and treatment outcomes.

Moderate dose radiotherapy effective in EORTC trial for patients with desmoid-type fibromatosis

A phase 2 EORTC trial for patients with inoperable desmoid-type fibromatosis has shown that moderate dose radiotherapy is an effective treatment for patients with such a rare type of tumor. The study results published in Annals of Oncology show that response after radiation therapy is slow, and that continuing regression is seen even after three years.

Mortality rates for emergency surgical admissions vary widely among hospitals in England

A new study reveals significant hospital-to-hospital variability in patient death rates following emergency surgical admissions in England. Published early online in the BJS (British Journal of Surgery), the study also found that survival rates were higher in hospitals with better resources.

Discovery of stone monument at El Perú-Waka' adds new chapter to ancient Maya history

Archaeologists tunneling beneath the main temple of the ancient Maya city of El Perú-Waka' in northern Guatemala have discovered an intricately carved stone monument with hieroglyphic text detailing the exploits of a little-known sixth-century princess whose progeny prevailed in a bloody, back-and-forth struggle between two of the civilization's most powerful royal dynasties, Guatemalan cultural officials announced July 16.

Spectrum Health study first to identify heart attack-causing plaque in living patients

GRAND RAPIDS, Mich., July 17, 2013 – We may be closer to predicting who is at risk for a heart attack, according to a recently published Spectrum Health study.

Researchers with Spectrum Health's Frederik Meijer Heart & Vascular Institute used new imaging technology on patients being treated for heart attacks. The imaging technology allowed researchers to identify the characteristic makeup, or signature, of arterial plaque blocking an artery and causing a heart attack.

The best defense against catastrophic storms: Mother Nature, say Stanford researchers

Extreme weather, sea level rise and degraded coastal systems are placing people and property at greater risk along the coast. Natural habitats such as dunes and reefs are critical to protecting millions of U.S. residents and billions of dollars in property from coastal storms, according to a new study by scientists with the Natural Capital Project at the Stanford Woods Institute for the Environment.

Empty decoys divert antibodies from neutralizing gene therapy in cell, animal studies

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene. The decoy was effective in animal studies, and if the approach succeeds in humans, it offers a potential new treatment for genetic diseases such as hemophilia, while advancing the broader field of gene therapy.

Cost of treating dizziness in the emergency room soars

A new Johns Hopkins research report says emergency room visits for severe dizziness have grown exponentially in recent years, with costs topping $3.9 billion in 2011 and projected to reach $4.4 billion by 2015. The investigators say roughly half a billion a year could be saved immediately if emergency room physicians stopped the routine and excessive use of head CT scans to search for stroke in dizzy patients, and instead used simple bedside physical exams to identify the small group of patients that truly needs imaging.

Brazilian government health care leads to declines in infant mortality

A paper in Health Affairs titled Brazil's Conditional Cash Transfer Program Associated With Declines In Infant Mortality Rates describes Brazil's Bolsa Família conditional cash transfer program, an example of recent actions by the Brazilian government to reduce poverty and inequality and increase access to health care among its poorer residents.