Culture

Mothers' excess pregnancy weight gain, elevated blood sugar 'imprint' obesity in children

PORTLAND, Ore., May 6, 2016 -- Children whose mothers gain excess weight or have elevated blood sugar during their pregnancies are more likely to become overweight or obese during their first decade of life, according to a new Kaiser Permanente study published today in Maternal and Child Health Journal.

Women undergoing TAVR have a different risk profile and greater survival rate than men

Orlando, Fla. - Data from one of the largest national registries of transcatheter aortic valve replacement (TAVR) patients shows that although women are more likely to experience vascular complications in the hospital, their one-year survival rate is more favorable than men. This STS/ACC TVT Registry™ analysis was presented today as a late-breaking clinical trial at the Society for Cardiovascular Angiography and Interventions (SCAI) 2016 Scientific Sessions in Orlando, Fla.

Young women at greater risk for adverse outcomes following PCI

Orlando, Fla. - Women younger than 55 years of age who undergo percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) are more likely to experience one-year adverse cardiovascular events due to risk factors such as diabetes and chronic kidney disease, yet they are less likely to receive potent antiplatelet therapy than men. The PROMETHEUS study found that outcomes for both men and women post-PCI are dependent on their baseline risk factors, not their sex.

Moderate sedation shows promise for TAVR patients

Orlando, Fla. - The largest observational study of percutaneous transfemoral transcatheter aortic valve replacement (TAVR) demonstrated that moderate sedation use is associated with improved patient outcomes, including lower 30-day mortality and shorter hospital stays, as compared to traditional general anesthesia. This STS/ACC TVT Registry™ analysis was presented today as a late-breaking clinical trial at the Society for Cardiovascular Angiography and Interventions (SCAI) 2016 Scientific Sessions in Orlando, Fla.

Penn study finds moderate sedation more effective than general anesthesia for TAVR patients

PHILADELPHIA - A new study finds the use of moderate sedation, in which patients do not need a breathing tube, leads to better clinical outcomes as compared to general anesthesia for patients undergoing transcatheter aortic valve replacement (TAVR).

DMP 'rheumatoid arthritis': Guidelines cover important health care aspects

On 28 April 2016 the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a search for evidence-based guidelines on the treatment of people with rheumatoid arthritis. The aim of the report is to identify those recommendations from current guidelines of high methodological quality that may be relevant for a potential new disease management programme (DMP) "rheumatoid arthritis". According to the results of the report the recommendations cover nearly all important health care aspects; however, rehabilitation measures are only addressed sporadically.

Blood thinners on 'as needed' basis is safe and effective for lowering stroke risk as compared to long-term use

PHILADELPHIA - Patients with atrial fibrillation (AF), a rapid irregular heartbeat caused by pooling blood in the heart which can lead to heart failure and stroke, are often treated with an ablation, a minimally invasive procedure used to remove the tissue which causes the pooled blood. Following this procedure, patients are often prescribed long-term, daily oral anticoagulation medications -- also known as blood thinners.

Apples or fries

There has been a lot of enthusiasm for nudging individuals to eat better without restricting choice by making healthy foods more visible, attractive, and convenient. One such effort is for restaurants to serve meals with a default healthy side, such as sliced apples instead of fries, while still allowing the customer to opt out of the healthy side in favor of their preferred side dish.

Antibody therapy opens door to potential new treatment for HIV

The development of antiretroviral therapy, a combination of drugs that slows the replication of HIV in the body, has transformed the treatment of this infection. What was once a certain death sentence is now a chronic condition that people can live with for decades.

But this therapy has drawbacks. There are side effects, including kidney problems, decreased bone density, and gastrointestinal problems. And if a person discontinues his or her treatment, even missing a few doses, the level of the virus in the body is able to rebound quickly.

Temple study examines whether compression stockings can prevent post-thrombotic syndrome

(Philadelphia, PA) - Deep vein thrombosis occurs when a blood clot forms in a vein, often in the deep veins of the legs, thigh or pelvis. Approximately half of people with this problem will develop post thrombotic syndrome -- a condition marked by pain, swelling, redness and chronic sores in the affected legs.

Research collaboration IDs serum biomarkers that predict preclinical IBD development and complications

Years before inflammatory bowel disease (IBD) is diagnosed and symptoms exist, biomarkers are already circulating that can help predict risk not only of disease development but also of complications, according to research published online last week, which will also appear in the June 15, 2016 print issue of Alimentary Pharmacology & Therapeutics.

RAND/Harvard study shows teledermatology increases patient access to specialized skin care

PALO ALTO, CALIFORNIA (May 5, 2016) - Teledermatology significantly improved access to specialized skin care for a group of patients that traditionally has limited options, according to an independent study led by researchers at the RAND Corporation and Harvard Medical School's Department of Health. The findings appear in a JAMA Dermatology article published online May 4.

Protein may predict response to immunotherapy in patients with metastatic melanoma

ROCHESTER, Minn. -- A protein called Bim may hold the clue to which patients may be successful on immunotherapy for metastatic melanoma, according to the results of a study by Mayo Clinic researchers led by senior author Haidong Dong, M.D., Ph.D., and published online in the May 5 edition of JCI Insight.

Achieving fish biomass targets: The key to securing a sustainable future for coral reefs

Scientists from WCS (Wildlife Conservation Society), University of Queensland, James Cook University, and Macquarie University have completed a massive study that will help communities and countries of the Western Indian Ocean measure and restore fish populations while identifying the best policies for achieving global sustainable and conservation targets.

Study: AF patients treated long term with warfarin at increased risk for dementia

SAN FRANCISCO, May 5, 2016 - A new study of more than 10,000 patients treated long term with the blood thinner, warfarin, reveals higher rates of dementia for patients with atrial fibrillation versus non-AF patients

The study, by researchers at the Intermountain Medical Center Heart Institute in Salt Lake City, found that atrial fibrillation patients treated long term with warfarin had higher rates of dementia, Alzheimer's disease and vascular dementia compared to anticoagulated non-atrial fibrillation patients.