DALLAS - Aug. 2, 2016 - UT Southwestern Medical Center researchers have found an important innate immunity role for a gene linked to a rare, fatal syndrome in children. Their study has implications for a much more common disease: tuberculosis.
The study results, posted online today in the journal Immunity, could lead to new therapies for arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome. It also suggests connections to tuberculosis (TB): a hard-to-treat bacterial illness that the World Health Organization calls "a top infectious disease killer worldwide."