CHAMPAIGN, Ill.-- Searching for the precise, complexly folded three-dimensional structure of a protein can be like hacking through a jungle without a map: a long, intensive process with uncertain direction. University of Illinois researchers developed a new approach, dubbed COMPASS, that points directly to a protein's likely structure using a combination of advanced molecular spectroscopy techniques, predictive protein-folding algorithms and image recognition software.
Led by U. of I. chemistry professor Chad Rienstra, the team published its results in the journal Structure.