A bile acid that can turn off a receptor in the gut has prevented and reversed fatty liver disease in mice, according to an international team of researchers. The compound may help treat certain metabolic disorders, such as Type 2 diabetes and obesity, as well.
Obese and diabetic mice fed glycine-beta muricholic acid -- Gly-MCA -- pills with a high-fat diet had significantly less fat and less insulin resistance than the untreated control group, according to Andrew Patterson, associate professor of molecular toxicology, Penn State.