Body

New study shows esophageal cancers driven by 'marginal gain' rather than speed

Wellcome Trust Sanger Institute scientists have shown that unexpectedly, oesophageal cancer cells do not divide faster than their normal neighbours. But unlike normal cells, the tumour cells produce slightly more dividing daughter cells than non-dividing ones, forming a tumour.

The study, published in Nature Cell Biology today, could lead to the development of new treatments for cancers that do not respond to current therapies which target fast-growing cells.

New types of African Salmonella associated with lethal infection

The first global-scale genetic study of Salmonella Enteritidis bacteria, which is a major cause of blood poisoning and death in Africa and food poisoning in the Western World, has discovered that there are in fact three separate types. Scientists at the Wellcome Trust Sanger Institute, Liverpool School of Tropical Medicine and University of Liverpool found two novel African types, which looked the same, but were genetically different from the Western type.

Religious actions convey pro-social intent, finds study

Religious expression has a central role in societies around the world, but exactly what role it plays isn't always clear. Santa Fe Institute Omidyar Postdoctoral Fellow Eleanor Power has an answer: whether it's walking across hot coals or simply going to church on Sunday, people who participate in religious acts send a potent signal to others that they're ready and willing to contribute to their communities.

Urban pumping raises arsenic risk in Southeast Asia

Large-scale groundwater pumping is opening doors for dangerously high levels of arsenic to enter some of Southeast Asia's aquifers, with water now seeping in through riverbeds with arsenic concentrations more than 100 times the limits of safety, according to a new study from scientists at Columbia University's Lamont-Doherty Earth Observatory, MIT, and Hanoi University of Science.

Is it your second cousin? Cotton swabs may tell you

Kyoto, Japan -- The precision of DNA testing portrayed on mystery television shows could soon become reality. With a new technique developed at Kyoto University, a simple swab sample can accurately confirm relatedness between two individuals as distant as second cousins. With more DNA datasets at hand, the method could be utilized to identify disaster victims in mass floods and tornadoes that destroy entire communities.

Canine hereditary disorders are more widespread than previously indicated

Genoscoper Ltd. has published in cooperation with the researchers of University of Helsinki and Pennsylvania (USA) so far the most comprehensive study on canine hereditary disorders. The research brings new information about genetic disorders causing diseases in different dog breeds. The results can be utilized both in dog breeding and veterinary diagnostics. The study was published on PLOS ONE on Aug. 15, 2016.

Sick animals limit disease transmission by isolating themselves from their peers

When animals get sick, they may change their behaviour, becoming less active, for example. The study's lead author, Patricia Lopes from the Department of Evolutionary Biology and Environmental Studies at the University of Zurich, says that previous research in wild animals has generally ignored how this change in behaviour may affect social contacts in a group and how, in turn, these changes can impact the transmission of a disease.

Sick mice are not avoided, but remove themselves from the group

Genetic regulation of the thymus function identified

Researchers at the universities of Basel and Oxford have for the first time identified all genes regulated by the protein Foxn1. The results show that Foxn1 not only plays a crucial role in development of the thymus in the embryo, but it also regulates vital functions in the developed, postnatal organ. The decryption of the protein's functions is important in the understanding and treatment of autoimmune diseases, vaccination responses in old age and defense against tumor cells. The study was published in the journal Nature Immunology.

Scientists challenge recommendation that men with more muscle need more protein

Sports nutrition recommendations may undergo a significant shift after research from the University of Stirling has found individuals with more muscle mass do not need more protein after resistance exercise.

Health and exercise scientists from Scotland's University for Sporting Excellence found no difference in the muscle growth response to protein after a full body workout between larger and smaller participants.

New global migration mapping to help fight against infectious diseases

Geographers at the University of Southampton have completed a large scale data and mapping project to track the flow of internal human migration in low and middle income countries.

Researchers from the WorldPop project at the University have, for the first time, mapped estimated internal migration in countries across three continents; Africa, Asia and Latin America and the Caribbean.

Pro-nuclear countries making slower progress on climate targets

A strong national commitment to nuclear energy goes hand in hand with weak performance on climate change targets, researchers at the University of Sussex and the Vienna School of International Studies have found.

A new study of European countries, published in the journal Climate Policy, shows that the most progress towards reducing carbon emissions and increasing renewable energy sources -- as set out in the EU's 2020 Strategy -- has been made by nations without nuclear energy or with plans to reduce it.

Hibernating pygmy-possums can sense danger even while dormant

What happens to hibernating or torpid animals when a bushfire rages? Are they able to sense danger and wake up from their energy-saving sleep to move to safety? Yes, says Julia Nowack of the University of New England in Australia, lead author of a study in Springer's journal The Science of Nature about the reaction of pygmy-possums in such instances. The study is the first to investigate in detail the physical response of hibernating animals to smoke and fire.

Elongation by contraction

Scientists from the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have discovered a new mechanism of cell boundary elongation. Elongation and contraction of the cell boundary is essential for directing changes in cell shape, which is required for the correct development of tissues and organs. The study was published in Current Biology on 11 August 2016.

How do contractile forces lengthen cell boundaries?

AGA answers call for quality colorectal cancer patient info

Bethesda, MD (Aug. 22, 2016) -- Patients depend on the internet for health information, but when it comes to colorectal cancer, currently available resources are not meeting their needs. A new study finds that there is a notable variation in accuracy, quality and readability of patient-oriented web information on colorectal cancer. Further, most websites lack important information regarding polyps and their importance for future follow-up surveillance colonoscopies.

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes

Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins move from one neuron to the next in lysosomal vesicles which travel along the "tunneling nanotubes" between cells. These findings were published in The EMBO Journal on Aug. 22, 2016.