Body

COLUMBUS, Ohio - The same mechanisms that that prevent people from having an inflammatory response to harmless environmental exposures in day-to-day life could also all allow rogue cancer cells to spread to the lungs, according to new research from The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James).

CHAPEL HILL - Nearly nine out of 10 physicians and researchers who helped develop a leading set of cancer care guidelines in the United States reported financial ties to the pharmaceutical and medical device industries, a University of North Carolina Lineberger Comprehensive Cancer Center study found.

SCIENTISTS have demonstrated for the first time the 'perfect storm' of conditions that cells need to start forming cancer, helping to explain why some organs are more susceptible to developing the disease, according to a new study published in Cell today (Thursday).

DURHAM, N.C. - The forward march of science often blunders into the realization that nature's way of doing things is a lot more complicated than we thought.

So it is apparently with the process that activates genes to start the machinery for manufacturing proteins, according to a team of Duke scientists.

LA JOLLA--Salk Institute scientists have discovered the holy grail of endless youthfulness--at least when it comes to one type of human kidney precursor cell. Previous attempts to maintain cultures of the so-called nephron progenitor cells often failed, as the cells died or gradually lost their developmental potential rather than staying in a more medically useful precursor state.

PASADENA, Calif., Aug. 25, 2016 -- A new Kaiser Permanente study found an increased risk for becoming overweight or obese among normal-weight 18-year-olds who lived in neighborhoods with lower education or income levels. The study, published today in Pediatric Obesity, found that over a four-year period, 25 percent of these young adults became overweight or obese.

Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. Curbing this infighting has the potential to make treatment more effective, according to a study led by researchers from NYU Langone Medical Center and its Perlmutter Cancer Center.

Proteins perform a wide range of tasks within cells. For everything to run smoothly, the cell must make sure that all the necessary proteins are available and that they are in good condition. Faulty proteins are labeled as such and then recycled. Ligase complexes are able to identify aberrant proteins and attach a small regulatory protein called ubiquitin (Ub) to mark them as faulty. However, further steps are needed before the protein degradation pathway is triggered.

CHAPEL HILL - A group of University of North Carolina Lineberger Comprehensive Cancer Center researchers is calling for an overhaul of the process that determines which cancer drugs used off-label -- or beyond their approved use -- are reimbursed by federally-funded health insurance in the United States.

PHILADELPHIA - A new biomaterial can be used to study how and when stem cells sense the mechanics of their surrounding environment, found a team led by Robert Mauck, PhD, the Mary Black Ralston Professor for Education and Research in Orthopaedic Surgery, in the Perelman School of Medicine at the University of Pennsylvania. With further development, this biomaterial could be used to control when immature stem cells differentiate into more specialized cells for regenerative and tissue-engineering-based therapies.

Google "telecommuting" and you'll find business articles like:

"Four reasons why telecommuting is bad for business" or: "Is telecommuting an effective way to work" and, of course: "Four reasons telecommuting is good for employees"

Clearly, the jury is still out on the practice. Some companies do it, some don't. Others, like Yahoo, used to do it but have now said no more.

Scientists have identified a new "multicomponent" virus -- one containing different segments of genetic material in separate particles -- that can infect animals, according to research published today in the journal Cell Host & Microbe.

Can the woolly mammoth be brought back from the dead? Scientists say it's only a matter of time.

In fact this year, the International Union for Conservation of Nature issued its first official set of guidelines on resurrecting extinct species. What's more, university research labs and non-governmental agencies have projects in motion to bring back extinct species. But is all of this a good idea?

Scientists have discovered an alternative way to create a stronger binding between pharmaceutical drugs and the part of the body they are targeting - a development that can be used to fight a variety of diseases, including breast cancer. The study published in PLOS Computational Biology shows that flexible molecules, instead of rigid ones, as previously thought, can bind more effectively to the proteins causing the disease.

BOSTON - (August 25, 2016) - Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis. There are no established drugs to improve angiogenesis in diabetes. However, researchers at Joslin Diabetes Center now have identified a gene called CITED2 in a molecular pathway that may offer targets for drugs that treat these conditions by strengthening angiogenesis.