Body

Most US adults say today's children have worse health than in past generations

ANN ARBOR, Mich. -- More than half of adults believe children today are more stressed, experience less quality family time and have worse mental and emotional health than children in past generations, according to the C.S. Mott Children's Hospital National Poll on Children's Health.

AACR: Life-preserver microbubbles float tumor cells for analysis

A University of Colorado Cancer Center study presented at the American Association for Cancer Research Annual Meeting 2016 demonstrates the use of gas microbubbles to selectively attach to and float circulating tumor cells from blood samples, allowing analysis of the isolated cells.

Study shows how TRK-fusion lung cancer escapes LOXO-101, offering new treatment strategies

A University of Colorado Cancer Center study presented at the American Association for Cancer Research Annual Meeting 2016 pinpoints ways that cancer cells evolve to resist the drug LOXO-101, a kinase inhibitor of the TRK-fusion genes that drive a subset of cancers. The drug is currently being evaluated in promising phase 1 and phase 2 clinical trials.

SPF30 sunscreens delay melanoma incidence in preclinical model

COLUMBUS, Ohio -- Application of sun protection factor 30 (SPF30) sunscreen prior to exposure to ultraviolet-B (UVB) light delayed melanoma onset in a mouse model of the disease, according to data from a team at The Ohio State University Comprehensive Cancer Center Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute. This data suggest that the mouse model can be used to identify new, more effective melanoma-preventing agents, according to principal investigator Christin Burd, PhD.

Study drug LOXO-101 shows tumor regression in varied cancers

A phase I study of the drug LOXO-101 appears to significantly reduce tumors in patients with varied types of genetically defined cancer, according to a study led by The University of Texas MD Anderson Cancer Center.

The results of the study, which followed patients with unique proteins called tropomyosin receptor kinase fusions (TRKs), were presented at the American Association for Cancer Research's annual meeting held April 16-20 in New Orleans.

Chips or cookies? Toddlers with sweet tooth more likely to experience weight gain

ANN ARBOR, Mich. -- Some say there's always room for dessert - but those who follow that motto young may be more likely to gain unhealthy weight, a new study suggests.

Toddlers who reached for cookies over chips when their bellies were full had a higher risk of body fat increases, University of Michigan researchers report in the May issue of Pediatrics.

Fewer romantic prospects may lead to riskier investments

Encountering information suggesting that it may be tough to find a romantic partner shifts people's decision making toward riskier options, according to new findings from a series of studies published in Psychological Science, a journal of the Association for Psychological Science.

Risk of second major osteoporotic fracture is greatest immediately after first fracture

Malaga, Spain - April 17, 2016 - Today, at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, an international research team presented the preliminary results of a new study which aimed to determine whether the predictive value of a past major osteoporotic fracture (MOF) for future MOF changed with time.

They studied a database of 118,872 men and women born between 1907 and 1935 who were part of the Reykjavik Study during 1967-1991. Data on all fractures from participant entry into the study until December 31, 2012 were extracted.

Study shows hip fracture risk rises in the 10 years after total knee replacement

Researchers from the Sahlgrenska Academy in Molndal, Sweden have published preliminary results of a fracture risk study, which was based on analysis of medical records from 1987 to 2002 covering the entire Swedish population born between 1902 and 1952.

UK study supports cardiovascular safety of calcium and vitamin D supplementation

UK researchers have presented a new study that supports the cardiovascular safety of calcium and vitamin D supplementation. The study was based on analysis of the UK Biobank, a very large study comprising 502,664 men and women aged 40-69 years.

Sarcopenia, which affects up to 20 percent of European seniors, may increase 63 percent by 2045

Today, at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases. researchers from the University of Liège, Belgium presented a study that reveals the enormous and growing burden of sarcopenia in Europe.

Sarcopenia is a disease associated with the ageing process. Hallmark signs of the disorder are loss of muscle mass and strength, which in turn affects balance, gait and overall ability to perform tasks of daily living.

Potential first-in-class treatment is well-tolerated in patients with chronic hepatitis B

April 16, 2016, Barcelona, Spain: New data presented today confirms that a novel first-in-class treatment for Hepatitis B, called NVR 3-778, is well-tolerated and can reduce levels of the virus' genetic material in the body when combined with pegylated interferon after four weeks of treatment. The updated Phase 1b trial results were presented today at The International Liver CongressTM 2016 in Barcelona, Spain.

Low fat diet helps postmenopausal women avoid deadly breast cancers

NEW ORLEANS - Women who stayed on a low fat diet for approximately eight years reduced their risk of death from invasive breast cancers and improved their survival rates when compared with women who had not followed the dietary regimen, according to a study presented at a clinical trial plenary session, entitled "Transformative Clinical Trials in Breast Cancer," at the American Association for Cancer Research (AACR) annual meeting.

Experimental drug guadecitabine found safe in patients with colorectal cancer

In a small, phase I clinical trial, Johns Hopkins Kimmel Cancer Center researchers say they show for the first time that the experimental drug guadecitabine (SGI-110) is safe in combination with the chemotherapy drug irinotecan and may overcome resistance to irinotecan in patients with metastatic colorectal cancer. Results of the study are expected to be presented April 17 at the American Association for Cancer Research (AACR) Annual Meeting 2016 in New Orleans (abstract CT017).

St. Jude Children's Research Hospital research at AACR Annual Meeting

St. Jude Children's Research Hospital research related to survivorship, precision medicine and a wide range of other topics will be presented and highlighted during the five-day American Association for Cancer Research (AACR) annual meeting that begins Saturday in New Orleans.