A team of researchers led by the University of Leicester has shed new light on how the regulation machinery that controls gene expression works by characterising a complex known as the NuRD complex.
The study, led by John Schwabe, Professor of Structural Biology and Head of Department of Molecular and Cell Biology at the University of Leicester and published in the journal eLIFE, focuses on three protein components which make up the core of the NuRD complex: MTA1, RBBP4 and HDAC1.