Body

Further clues in the fight against Chronic Fatigue Syndrome

New findings regarding the pathology of Chronic Fatigue Syndrome (CFS) are bringing Griffith University researchers closer to identifying the cause of this disabling illness.

This is the news from a team at the National Centre for Neuroimmunology and Emerging Diseases at the Menzies Health Institute Queensland.

Professors Marshall-Gradisnik and Don Staines and their research team have identified significant impairments in cellular function of people with CFS.

Loss of chromosome 8p governs tumor suppression and drug response

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

Nation's beekeepers lost 44 percent of bees in 2015-16

Beekeepers across the United States lost 44 percent of their honey bee colonies during the year spanning April 2015 to April 2016, according to the latest preliminary results of an annual nationwide survey. Rates of both winter loss and summer loss--and consequently, total annual losses--worsened compared with last year. This marks the second consecutive survey year that summer loss rates rivaled winter loss rates.

Graphene flakes to calm synapses

The laboratory of SISSA's Laura Ballerini in collaboration with the University of Trieste, the University of Manchester and the University of Castilla -la Mancha, has discovered a new approach to modulating synapses. This methodology could be useful for treating diseases in which electrical nerve activity is altered. Ballerini and Maurizio Prato (University of Trieste) are the principal investigators of the project within the European flagship on graphene, a far-reaching 10-year international collaboration (one billion euros in funding) that studies innovative uses of the material.

University of Leicester scientists identify way to 'sniff' ripeness of fruit

Scientists from the University of Leicester have, for the first time, identified a way to 'sniff' the ripeness of mangoes.

They have identified the unique chemical signature of ripening for mangoes and published their research in the academic journal Metabolomics.

BPD strongly associated with risk of STI/HIV transmission for straight black men in jail

Sexually transmitted infections (STI), including HIV, disproportionately affect incarcerated populations. In 2010, over 90% of the inmates living with HIV in U.S. prisons were men and the prevalence of STIs such as chlamydia, gonorrhea, and syphilis, continues to be much higher among male inmates as compared to the U.S. population at large.

Scientists digitally mimic evolution to create novel proteins

CHAPEL HILL - Proteins are nature's machines. They provide oxygen to power our muscles, catalyze reactions that help us extract energy from food, and fend off infections from bacteria and viruses. For decades, scientists have searched for ways to design new proteins that can serve specific purposes in medicine, research, and industry. Now, researchers at the University of North Carolina School of Medicine have developed a method that creates novel proteins by stitching together pieces of already existing proteins.

Potential target in treatment of oral cancer discovered

(Boston)--For the first time, researchers have identified a reliable marker (PDGFRβ) to detect carcinoma-associated fibroblasts (cells within the tumor that encourage growth and metastasis) (CAFs) in oral cancer tissues. With this discovery, anti-PDGFRβ treatment could soon be combined with existing tumor treatments to provide a more effective cancer therapy.

Research discovers mechanism that causes cancer cells to escape from the immune system

Under normal circumstances, the immune system recognizes and successfully fights cancer cells, eliminating them as they develop. However, sometimes the process breaks down and tumors form, and now we know why. Researchers at the Texas A&M Health Science Center found that when cancer cells are able to block the function of a gene called NLRC5, they are able to evade the immune system and proliferate, according to research published today in the Proceedings of the National Academy of Sciences (PNAS).

How US police departments can clear more homicides

EAST LANSING, Mich. -- Only about 65 percent of homicides in the United States are solved - down 15 percent from the mid-1970s - but a new study led by a Michigan State University criminologist examines how some police departments are getting it right.

With food, similar substitutes are less satisfying

Sometimes the one thing we want isn't available and we have to settle for second best--instead of picking the closest substitute, new research suggests we'd be better off picking a not-so-similar alternative.

Findings from a series of studies published in Psychological Science, a journal of the Association for Psychological Science, indicate that even though people tend to prefer the option that's most similar to the item they can't have, they're likely to be more satisfied with the option that diverges a bit.

Scientists report world's first herbivorous filter-feeding marine reptile

Some strange creatures cropped up in the wake of one of Earth's biggest mass extinctions 252 million years ago. In 2014, scientists discovered a bizarre fossil--a crocodile-sized sea-dwelling reptile, Atopodentatus unicus, that lived 242 million years ago in what today is southwestern China. Its head was poorly preserved, but it seemed to have a flamingo-like beak. However, in a paper published May 6 in Science Advances, Dr.

Fewer overweight or obese children in Canada after years of increased rates

After years of increases, the rates of children who are overweight or obese are declining in Canada, according to new research in CMAJ (Canadian Medical Association Journal)

Between 1978 and 2004, there was a significant increase in Canada in the rates of children who are obese or overweight aged 2 to 17 years, from 23.3% to 34.7%, using the World Health Organization's (WHO) revised growth curves.

International collaboration for genome analysis leads to clues about rare cancer

ANN ARBOR, Mich. - Researchers from across the globe have joined together to improve understanding about one of the most rare -- and lethal -- types of cancer.

Teams from 39 institutions in Europe, North America, South America and Australia collected and analyzed 91 samples of adrenocortical carcinoma. They performed a comprehensive genomic analysis as part of The Cancer Genome Atlas Research Network.

Fooling the test: Antibiotic-resistant bacteria that look susceptible

A diagnostic test used by hospitals says a recently isolated strain of bacteria is susceptible to the last resort antibiotic colistin. But the strain actually ignores treatment with colistin, causing lethal infections in animals.

Through "heteroresistance," a genetically identical subpopulation of antibiotic-resistant bacteria can lurk within a crowd of antibiotic-susceptible bacteria. The phenomenon could be causing unexplained treatment failures in the clinic and highlights the need for more sensitive diagnostic tests, researchers say.