Body

Mass. General study links developmental and lipid handling pathways in C. elegans

A Massachusetts General Hospital (MGH) research team reports finding that a previously unknown interaction between metabolic pathways in two different tissues within the C.elegans roundworm triggers a key step in maturation.

New study shows differences in blood pressure variation across ethnicity

BINGHAMTON, NY - Differences in circadian blood pressure variation due to a combination of genetic and cultural factors may contribute to ethnic differences in cardiovascular morbidity, according to new research from Binghamton University, State University of New York.

Study finds first evidence that PD-1 antibody could help men with metastatic prostate cancer

Restoring tumor-specific immunity is a treatment strategy that works well in melanoma and lung cancer patients. Now a new study out of the OHSU Knight Cancer Institute is reviving hope that the approach also may help men with life-threatening prostate cancer.

It is a surprising turnaround because prior results in men with aggressive, advanced-stage prostate cancer showed no evidence of anti-tumor activity with immune therapies that work by blocking PD-1 signals.

UNC professor identifies research priorities for National Institutes of Health

CHAPEL HILL, NC - More than 20 percent of all blood clots in veins occur in cancer patients. These clots, also known as venous thromboembolism (VTE), pose serious threats for cancer patients. Nigel Key, MB, ChB, FRCP, director of the UNC Hemophilia and Thrombosis Center, is lead author of an advisory opinion on research priorities to address VTE in cancer patients.

Sugar-binding protein galectin-9 found to be a new weapon to cure HIV

July 13, 2016, San Francisco, CA-- The ultimate impediment to a cure for HIV infection is the presence of latent, HIV-infected cells, which can reawaken and produce new virus when antiretroviral drug therapy is stopped. These latent, HIV-infected cells are untouched by antiretroviral therapy and are unseen by the immune system.

Differences in CEO leadership style, company culture improve firm performance, study finds

ATLANTA--Chief executive officers (CEOs) should have a different leadership style from an organization's culture in order to improve a firm's performance, according to researchers at Georgia State University, Arizona State University, the University of South Australia and Auckland University of Technology.

Early preschool bedtimes cut risk of obesity later on

COLUMBUS, Ohio - Preschoolers who are regularly tucked into bed by 8 p.m. are far less likely to become obese teenagers than young children who go to sleep later in the evening, new research has found.

Bedtimes after 9 p.m. appeared to double the likelihood of obesity later in life, according to a study from The Ohio State University College of Public Health.

"For parents, this reinforces the importance of establishing a bedtime routine," said Sarah Anderson, lead author and associate professor of epidemiology.

New opioid use in older adults with COPD associated with increased risk of death

TORONTO, July 14, 2016 - Older adults with chronic obstructive pulmonary disease who start using opioids have a more than two-fold higher risk of dying from a respiratory-related complication compared to non-opioid users, St. Michael's Hospital researchers have found.

When researchers looked specifically at more potent opioids, they found the risk for respiratory-related death was five times higher for new opioid users compared to non-opioid users.

Weight loss can lower levels of some proteins associated with cancer

Bottom Line: Overweight and obese women who lost weight through diet and exercise lowered the levels of certain proteins in their blood that play a role in angiogenesis, the process of blood vessel growth that can promote the growth and survival of cancer cells.

Journal in Which the Study was Published: Cancer Research, a journal of the American Association for Cancer Research

Author: Catherine Duggan, PhD, principal staff scientist in the Public Health Sciences Division at the Fred Hutchinson Cancer Research Center in Seattle, Washington.

Forty years of the Nurses' Health Study: An evidence goldmine with a long-lasting legacy

It started in 1976 as an investigation into the potential health consequences of oral contraceptives, but the long-running Nurses' Health Study has yielded increasingly greater benefits to scientific knowledge of health and disease, according to a paper published today in the journal Public Health Research & Practice.

Losing weight lowered levels of proteins associated with tumor growth

SEATTLE - Overweight or obese women who lost weight through diet or a combination of diet and exercise also significantly lowered levels of proteins in the blood that help certain tumors grow, according to a Fred Hutchinson Cancer Research Center study published July 14 in Cancer Research, a journal of the American Association for Cancer Research.

New guidelines OK less antibiotics for hospital-acquired, ventilator-associated pneumonia

AT A GLANCE

PrEP can reduce new HIV cases by a third among MSM over next 10 years

A daily pill to prevent HIV infection can reduce new cases among men who have sex with men (MSM) by a third in the U.S. over the next 10 years, according to a new modeling study published in The Journal of Infectious Diseases and available online. The expected significant drop in HIV incidence, however, will depend on clinicians prescribing the medication according to federal guidelines and on patients using it as directed.

Early preschool bedtimes cut risk of obesity later on

COLUMBUS, Ohio - Preschoolers who are regularly tucked into bed by 8 p.m. are far less likely to become obese teenagers than young children who go to sleep later in theevening, new research has found.

Bedtimes after 9 p.m. appeared to double the likelihood of obesity later in life, according to a study from The Ohio State University College of Public Health.

"For parents, this reinforces the importance of establishing a bedtime routine," said Sarah Anderson, lead author and associate professor of epidemiology.

Feather-munching bacteria damage wild bird plumage

A new study in The Auk: Ornithological Advances links feather-degrading bacteria to damaged plumage on wild birds for the first time, offering new insights into how birds' ecology and behavior might affect their exposure to these little-studied microbes.