Body

Metastatic prostate cancer cases skyrocket

  • Highest increase among men ages 55 to 69, who could benefit the most from screening and early treatment
  • Disease is more advanced when finally diagnosed
  • "Screening saves lives," urologists stress. "If I were a patient, I would want to be vigilant."

Chimpanzees: Travel fosters tool use

Chimpanzees travelling far and for longer time periods use tools more frequently to obtain food. This conclusion results from an analysis of seven years of field experiments conducted at the Department of Comparative Cognition at the University of Neuchâtel and the Swiss Centre for Affective Sciences at the University of Geneva (UNIGE), Switzerland.

Mass. General study reveals how the body disposes of red blood cells, recycles iron

What happens when red blood cells become damaged or reach the end of their normal life span, and how is the iron required for carrying oxygen recycled? A new study led by Massachusetts General Hospital (MGH) investigators contradicts previous thinking about where and how worn-out red blood cells are disposed of and their iron retained for use in new cells. Their findings, being published online in Nature Medicine, may lead to improved treatment or prevention of anemia or iron toxicity.

Bariatric surgery associated with improved mobility, less walking pain

A new study published online by JAMA Pediatrics suggests bariatric surgery was associated with faster walking by teens, less walking-related musculoskeletal pain and lower heart rates as soon as six months following surgery and as long as two years after surgery.

Like adults, teens are not immune to the consequences of severe obesity, which can exacerbate functional mobility limitations and lead to a decline in physical activity because of the resulting musculoskeletal pain.

Poor African-American men have lowest likelihood of overall survival

African American men living below poverty had the lowest overall survival in a study that examined the effects of sex, race and socioeconomic status on overall mortality, according to an article published online by JAMA Internal Medicine.

NIH scientists discover that defective HIV DNA can encode HIV-related proteins

Investigators from the National Institutes of Health have discovered that cells from HIV-infected people whose virus is suppressed with treatment harbor defective HIV DNA that can nevertheless be transcribed into a template for producing HIV-related proteins. This finding may affect scientists' understanding of the long-term effects of HIV infection and what a cure would require.

Synthetic membranes created to mimic properties of living cells

Biochemists at the University of California San Diego have developed artificial cell membranes that grow and remodel themselves in a manner similar to that of living mammalian cells.

Researchers create means to monitor anthropogenic global warming in real time

A research team including a Scripps Institution of Oceanography at the University of California San Diego climate scientist simulated in a computer model, for the first time, the realistic evolution of global mean surface temperature since 1900.

In doing so, the researchers also created a new method by which researchers can measure and monitor the pace of anthropogenic global warming, finding that the contribution of human activities to warming in the surface waters of the Pacific Ocean can be distinguished from natural variability.

Dual antigen targeting may improve CAR T cell cancer therapy

Chimeric antigen receptor T cells (CAR T cells) are a promising immunotherapy approach to cancer treatment in which a patient's own immune cells attack tumors by targeting an identifying marker, or antigen, that is displayed at high levels on cancerous cells. However, CAR T cells that target a single antigen have had mixed results in clinical trials, which may be due to ongoing variability in the antigens that tumors display.

Ridiculously cute mouse lemurs hold key to Madagascar's past

Today, Madagascar is home to a mosaic of different habitats--a lush rainforest in the east and a dry deciduous forest in the west, separated by largely open highlands. But the island off the southeast coast of Africa hasn't always been like that--a new study published in the Proceedings of the National Academy of Sciences announces that these two ecologically different portions of the island were once linked by a patchwork of forested areas. And to figure it out, the scientists analyzed the DNA of some of the cutest animals on earth--mouse lemurs.

The pains and strains of a continental breakup

Every now and then in Earth's history, a pair of continents draws close enough to form one. There comes a time, however, when they must inevitably part ways.

Now scientists at Australia's EarthByte research group, in collaboration with the German Research Centre for Geosciences, have revealed the underlying mechanics of a continental breakup when this time arrives in a supercontinent's life cycle.

Scientists discover how proteins in the brain build-up rapidly in Alzheimer's

Cambridge researchers have identified - and shown that it may be possible to control - the mechanism that leads to the rapid build-up of the disease-causing 'plaques' that are characteristic of Alzheimer's disease.

What are gut bacteria doing in critically ill lungs? New discovery could change ICU care

ANN ARBOR, Mich. -- No one knows for sure how they got there. But the discovery that bacteria that normally live in the gut can be detected in the lungs of critically ill people and animals could mean a lot for intensive care patients.

Today, scientists are reporting that they found gut bacteria in the deepest reaches of failing lungs -- an environment where they normally aren't found and can't survive. The more severe the patients' critical illness, the more their usual lung bacteria were outnumbered by the misplaced gut bugs.

Some adolescent cancer survivors may require more comprehensive mental health screening

Most adolescent survivors of childhood cancer have no reported psychological symptoms, but an analysis led by St. Jude Children's Research Hospital found that those who do often have multiple symptoms and distinct symptom profiles. The findings, which appear today in the Journal of Clinical Oncology, highlight strategies to improve mental health screening and interventions.

Study identifies rare genetic syndrome associated with infections and lung disease in infants

An international team of researchers has identified a new rare genetic condition - a chromosome breakage syndrome associated with severe infections and lung disease in infants. The discovery provides an explanation for this deadly pulmonary disease, possibilities to diagnose it and opportunities for developing alternate ways to treat it. The results appear today in the Journal of Clinical Investigation.