Seoul, Republic of Korea - Today at the 94th General Session & Exhibition of the International Association for Dental Research, researcher Angus Walls, Edinburgh Dental Institute, Scotland, UK, will give a Keynote Address titled "What is the Role of Diet in Caries Prevention?" The IADR General Session is being held in conjunction with the 3rd Meeting of the IADR Asia Pacific Region and the 35th Annual Meeting of the IADR Korean Division.
Dental caries are caused by bacterial fermentation of dietary sugars that result in the production of acids just below the critical pH for demineralization of enamel and dentine. This process is dynamic because saliva is an efficient remineralizing solution that can repair acid-mediated demineralization. However, there are limits to the extent of demineralization that can be repaired by the action of saliva, and this ability is impaired in people with xerostomia. Strategies for caries prevention can have two approaches, prevention of demineralization and enhancement of remineralization. Evidence for the benefits of fluorides, that act largely by enhancing remineralization, is strong in terms of their use in toothpastes, with water fluoridation and as topical agents, supported by compelling epidemiology long-term observational studies and RCTs. The evidence against sugars consumption, to reduce demineralization, is less strong with mainly observational studies and cross-sectional epidemiology and few if any RCTs.
The research results determined that fluorides work and are effective at preventing caries. The effects of reducing sugars intake are modified by the action of fluoride but the two approaches can work synergistically to reduce caries activity. The use of fluorides alone cannot prevent caries in the presence of a high sugars diet. This is a particular problem in people with impaired salivary defense because of xerostomia.
Source: International & American Associations for Dental Research