Sanjiv Gambhir (Stanford University Medical Center) and colleagues describe a linear one-compartment mathematical model that allows estimation of minimal detectable tumor sizes based on blood tumor biomarker assays.Citation: Lutz AM, Willmann JK, Cochran FV, Ray P, Gambhir SS (2008) Cancer screening: A mathematical model relating secreted blood biomarker levels to tumor sizes. PLoS Med 5(8): e170. doi:10.1371/journal.pmed.0050170IN YOUR COVERAGE PLEASE USE THIS URL TO PROVIDE ACCESS TO THE PUBLISHED PAPER: http://medicine.plosjournals.org/perlserv/?request=get-document&doi:10.1371/journal.pmed.0050170
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Source: Public Library of Science