Earth

Is it possible to simultaneously address the increase of the concentration of carbon dioxide (CO2) in the atmosphere and the resulting acidification of the oceans? The research of the project DESARC-MARESANUS, a collaboration between the Politecnico di Milano and the CMCC Euro-Mediterranean Center on Climate Change Foundation, explores the feasibility of this process, its chemical and environmental balance, and the benefits for the marine sector, focusing on the Mediterranean basin.

Electrochemical processes could be used to convert CO2 into useful starting materials for industry. To optimise the processes, chemists are attempting to calculate in detail the energy costs caused by the various reaction partners and steps. Researchers from Ruhr-Universität Bochum (RUB) and Sorbonne Université in Paris have discovered how small hydrophobic molecules, such as CO2, contribute to the energy costs of such reactions by analysing how the molecules interact in water at the interface.

Scientists at the Walter Reed Army Institute for Research demonstrated the potential of a novel blood test for cathepsin B, a well-studied protein important to brain development and function, as an indicator for a range of disease states.

It cannot be denied that, over the past few decades, the miniaturization of electronic devices has taken huge strides. Today, after pocket-size smartphones that could put old desktop computers to shame and a plethora of options for wireless connectivity, there is a particular type of device whose development has been steadily advancing: wearable biosensors. These tiny devices are generally meant to be worn directly on the skin in order to measure specific biosignals and, by sending measurements wirelessly to smartphones or computers, keep track of the user's health.

Researchers from North Carolina State University have found a way to fine-tune the molecular assembly line that creates antibiotics via engineered biosynthesis. The work could allow scientists to improve existing antibiotics as well as design new drug candidates quickly and efficiently.

Bacteria - such as E. coli - harness biosynthesis to create molecules that are difficult to make artificially.

After interviewing various stakeholders from public and private healthcare systems (in Lithuania and the US), researchers Dr Agne Gadeikiene, Prof Asta Pundziene, Dr Aiste Dovaliene from Kaunas University of Technology (KTU), Lithuania designed a detailed structure revealing added value of remote healthcare services, i.e. telehealth. Adopting the concept of value co-creation common in business research to healthcare, the scientists claim that this is the first comprehensive analysis of this kind in the healthcare field involving two different healthcare systems.

What The Study Did: Changes in quality of diet from different sources of food among U.S. children and adults from 2003 to 2018 were examined in this survey study.

Authors: Junxiu Liu, Ph.D., of the Icahn School of Medicine at Mount Sinai in New York, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2021.5262)

What The Study Did: Researchers compared the risk of death between infants with and without prenatal opioid exposure and also the difference in risk if diagnosed with neonatal opioid withdrawal syndrome.

Authors: JoAnna K. Leyenaar, M.D., Ph.D., M.P.H., of Children's Hospital at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

Convenience and access win out over reputation when people over 50 look for a doctor for themselves, a new study finds.

But online ratings and reviews of physicians play an important role, and should receive attention from providers and policymakers, the researchers say.

About 20% of older adults called such ratings very important to them, but 43% said they had checked such reviews in the past for physicians they were considering for themselves.

Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations--mutations--that affect how genes act and function. Added together, millions of small genetic variations make it hard to predict how a particular mutation will impact any individual. Cold Spring Harbor Laboratory (CSHL) Professor and Howard Hughes Medical Institute Investigator Zach Lippman showed how genetic variations in tomatoes can influence the way a specific mutation affects the plant.

A unique residential study has concluded that, contrary to perceived wisdom, people with eating disorders do not lose self-control - leading to binge-eating - in response to stress. The findings of the Cambridge-led research are published today in the Journal of Neuroscience.

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer. The scientists targeted a vulnerability in how the cancer cells reproduce, increasing already high levels of replication stress ¬¬-- a hallmark of out-of-control cell growth in many cancers that can damage DNA and force cancer cells to constantly work to repair themselves. In a small clinical trial, the drug duo shrank the tumors of SCLC patients.

BEER-SHEVA, Israel...April 13, 2021 - Researchers at Ben-Gurion University of the Negev (BGU) have for the first time identified new drug candidates based on molecules isolated from probiotic Kefir yogurt for combating pathogenic bacteria and treating various inflammatory conditions, including inflammatory bowel disease (IBD) and COVID-19 related cytokine storms.

The research, published in Microbiome, a leading peer-reviewed publication was led by Orit Malka, a Ph.D. student of Prof. Raz Jelinek, GU vice president and dean for research and development.

GEOGRAFI A new study by a University of Copenhagen researcher finds that thawing permafrost in Alaska causes colder water in smaller rivers and streams. This surprising consequence of climate change could affect the survival of fish species in the Arctic's offshore waters.

Arctic stream

The study's researchers discovered that thawing permafrost causes groundwater to run deeper, where it becomes cooler than when it flows near the soil surface.

Researchers at the University of Calgary and The Hospital for Sick Children (SickKids), in Toronto, have discovered genetic risk factors for OCD that could help pave the way for earlier diagnosis and improved treatment for children and youth.