Earth
A new review published online today in the journal Addiction has compiled the best, most up-to-date source of information on alcohol, tobacco, and illicit drug use and the burden of death and disease. It shows that in 2015 alcohol and tobacco use between them cost the human population more than a quarter of a billion disability-adjusted life years, with illicit drugs costing a further tens of millions.
Thursday, May 10, 2018, Baltimore, MD - Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for target identification, drug discovery and aging research announces the publication of a new research paper in Molecular Pharmaceutics journal titled "Adversarial Threshold Neural Computer for Molecular De Novo Design".
A new study has discovered that horses were first domesticated by descendants of hunter-gatherer groups in Kazakhstan who left little direct trace in the ancestry of modern populations. The research sheds new light on the long-standing "steppe theory" on the origin and movement of Indo-European languages made possible by the domestication of the horse.
The domestication of the horse was a milestone in human history that allowed people, their languages, and their ideas to move further and faster than before, leading both to widespread farming and to horse-powered warfare.
A study by Massachusetts General Hospital (MGH) investigators has found, for the first time in humans, that patients with chronic sciatica - back pain that shoots down the leg - have evidence of inflammation in key areas of the nervous system. In their paper published in the May issue of the journal Pain, the research team reports finding that average levels of a marker of neuroinflammation were elevated in both the spinal cord and the nerve roots of patients with chronic sciatica.
(Geneva, 10 May, 2018) Targeted probiotic supplementation in breastfed infants can significantly reduce the potential for antibiotic resistance, new research presented today at the 51st ESPGHAN Annual Meeting shows [i].
PHILADELPHIA - Different Parkinson's-related brain disorders, called synucleionpathies, are characterized by misfolded proteins embedded in cells. Researchers in the Perelman School of Medicine at the University of Pennsylvania found that the type of brain cell afflicted dictates which pathological form of α-synuclein (α-syn) protein becomes the disease culprit. The team's results were published this week in Nature.
Scientists have shone new light on how the human brain uses past experiences and generalizes them to future events, helping us safely navigate the world around us, a study in eLife reveals.
Our ability to 'generalize' is an important survival technique, but over-generalizing from bad events could explain why some people fear and then avoid scenarios that are not actually dangerous. This over-avoidance has been identified as a significant factor in anxiety, obsessive-compulsive disorder, chronic pain and depression.
TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.
ONC201 was originally identified as a small molecule that inhibits both Akt and ERK, resulting in dephosphorylation of Foxo3a and thereby induces TRAIL transcription.
For years, doctors have associated the BRCA1 and BRCA2 gene mutations with an increased risk of breast cancer.
But researchers at Texas A&M University have now identified another gene that may have an impact on breast cancer--associated with the body's circadian rhythm.
ANN ARBOR, Mich. - Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face.
And despite affecting 1 out of 200 adults over the age of 65 in the United States, general awareness of IPF is low.
Leopards, top predators of the African savannah, are known to feed on a variety of prey species. These include smaller and medium-sized mammals such as impala, gemsbok, kudus and warthogs but they can also target relatively small "appetizers" such as hares.
Researchers from North Carolina State University have demonstrated a connection between the expression of the HMGA2 gene and body size in pigs. The work further demonstrates the gene's importance in body size regulation across mammalian species, and provides a target for gene modification.
New Oxford University research has called for an 'open-skies policy' around the availability of high resolution satellite imagery of Israel and Palestine.
NEW YORK...May 3, 2018 - Researchers from Ben-Gurion University of the Negev (BGU) in Beer-Sheva, Israel have demonstrated for the first time the feasibility of a robotic system that plays Tic Tac Toe with rehabilitation patients to improve real-life task performance.
A new study of chemical reactions that occur when organic matter decomposes in freshwater lakes has revealed that the debris from trees suppresses production of methane - while debris from plants found in reed beds actually promotes this harmful greenhouse gas.
As vegetation in and around bodies of water continues to change, with forest cover being lost while global warming causes wetland plants to thrive, the many lakes of the northern hemisphere - already a major source of methane - could almost double their emissions in the next fifty years.