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Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with epigenetic agents.
Subsequently, the progenitor stem-like cells were directly differentiated into endothelial, mesenchymal stem, and osteogenic cells that constitute the periodontal ligament.
Background
There are some tasks that traditional robots -- the rigid and metallic kind -- simply aren't cut out for. Soft-bodied robots, on the other hand, may be able to interact with people more safely or slip into tight spaces with ease. But for robots to reliably complete their programmed duties, they need to know the whereabouts of all their body parts. That's a tall task for a soft robot that can deform in a virtually infinite number of ways.
Tsukuba, Japan - Researchers from the Department of Applied Physics at the University of Tsukuba demonstrated second-order nonlinear optical effects in diamonds by taking advantage of internal color center defects that break inversion symmetry of diamond crystal. This research may lead to faster internet communications, all-optical computers, and even open a route to next generation quantum sensing technologies.
WASHINGTON--Among women who develop diabetes during pregnancy, night owls have a higher risk of complications for mother and baby than early birds do, according to a study whose results will be presented at ENDO 2021, the Endocrine Society's annual meeting.
WASHINGTON--Addressing sleep symptoms during menopause may reduce susceptibility to weight gain, according to a small study presented virtually at ENDO 2021, the Endocrine Society's annual meeting.
WASHINGTON--Higher levels of the stomach-derived hormone ghrelin, which stimulates appetite, predict a greater preference for smaller immediate monetary rewards over larger delayed financial rewards, a new study finds. The study results will be presented at ENDO 2021, the Endocrine Society's annual meeting.
In a world first, a cross-institutional research collaboration has used a two-photon microscope (*1) with a combination of calcium imaging (*2) and holographic stimulation (*3) to reveal that the functional connectivity between neurons located in the primary somatosensory cortex is increased in response to acute pain.
PITTSBURGH, March 19, 2021 - Non-circulating memory T cells, whose main function is to provide local protection against re-infection, contribute to chronic transplant rejection, University of Pittsburgh School of Medicine researchers reveal in a paper published today in Science Immunology.
CAMBRIDGE, MA -- Many viruses infect their hosts through mucosal surfaces such as the lining of the respiratory tract. MIT researchers have now developed a vaccination strategy that can create an army of T cells that are ready and waiting at those surfaces, offering a quicker response to viral invaders.
The researchers showed that they could induce a strong memory T cell response in the lungs of mice by giving them a vaccine modified to bind to a protein naturally present in mucus. This can help ferry the vaccine across mucosal barriers, such as the lining of the lungs.
Tokyo, Japan - Researchers from Tokyo Metropolitan University have devised and implemented a simplified algorithm for turning freely drawn lines into holograms on a standard desktop CPU. They dramatically cut down the computational cost and power consumption of algorithms that require dedicated hardware. It is fast enough to convert writing into lines in real-time, and makes crisp, clear images that meet industry standards. Potential applications include hand-written remote instructions superimposed on landscapes and workbenches.
Nearly two-thirds of middle-aged and older adults in Canada report adverse childhood experiences
Hamilton, ON (Mar. 19, 20121) - New research from McMaster University has found that roughly three in every five Canadian adults aged 45 to 85 have been exposed to childhood abuse, neglect, intimate partner violence or other household adversity.
The research, which estimates the prevalence of a broad range of adverse childhood experiences, was published in CMAJ Open.
Due to their tissue-like mechanical properties, hydrogels are being increasingly used for biomedical applications; a well-known example are soft contact lenses. These gel-like polymers consist of 90 percent water, are elastic and particularly biocompatible. Hydrogels that are also electrically conductive allow additional fields of application, for example in the transmission of electrical signals in the body or as sensors.
Researchers at the Paul Scherrer Institute PSI have for the first time observed photochemical processes inside the smallest particles in the air. In doing so, they discovered that additional oxygen radicals that can be harmful to human health are formed in these aerosols under everyday conditions. They report on their results today in the journal Nature Communications.
Sabrina L. Spencer, PhD, is a CU Boulder researcher and a CU Cancer Center member. Spencer recently won two awards: the Damon Runyon-Rachleff Innovation Award (from the Damon Runyon Cancer Research Foundation) and the Emerging Leader Award (from The Mark Foundation for Cancer Research).
Binge drinking in adolescence is associated with changes in the volume of the cerebellum in young adulthood, a new study from the University of Eastern Finland and Kuopio University Hospital shows. Earlier studies have shown that excessive, long-term alcohol consumption causes damage to the cerebellum in adults, but there is very little data on the effects of adolescent drinking on the cerebellum. The findings were published in Alcohol.