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Results from the first experimental arm using veliparib as part of total neoadjuvant therapy (induction chemotherapy followed by chemoradiotherapy and surgery; TNT) in patients with locally advanced rectal adenocarcinoma on the NRG Oncology Phase II clinical trial NRG-GI002 were recently presented at the American Society of Clinical Oncology (ASCO) Annual Meeting. Results were reported on the primary endpoint of pathological regression via the neoadjuvant rectal cancer (NAR) score, a short-term clinical trial surrogate endpoint.
The world’s top 10 crops — barley, cassava, maize, oil palm, rapeseed, rice, sorghum, soybean, sugarcane and wheat — supply a combined 83 percent of all calories produced on cropland. Yields have long been projected to decrease in future climate conditions. Now, new research shows climate change has already affected production of these key energy sources — and some regions and countries are faring far worse than others.
A study by UCLA psychologists provides strong evidence that a certain region of the brain plays a critical role in memory recall. The research, published in the Journal of Cognitive Neuroscience, also shows for the first time that using an electrical current to stimulate that region, the left rostrolateral prefrontal cortex, improves people's ability to retrieve memories.
New Rochelle, NY, May 30, 2019--The body's endocannabinoid system, due to the critical role it plays in regulating neurotransmitter signaling, is an enticing target for drug development against disorders associated with anxiety, stress, and repetitive behaviors, such as obsessive-compulsive disorder (OCD).
In ongoing research to find a treatment for acute kidney injury, Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have further advanced a promising approach using therapeutic factors produced by stem cells by creating a more efficient delivery method that would improve tissue regeneration.
WFIRM researchers wanted to determine if any of the growth factors could lead to kidney function recovery. They developed a gel-based system that contained a cocktail of stem cell derived growth factors.
PHILADELPHIA--Growing up in poverty and experiencing traumatic events like a bad accident or sexual assault can impact brain development and behavior in children and young adults.
Child deaths have fallen in Brazil following complete smoking bans in public places, according to a new study.
Its authors, from Imperial College London, the Brazilian National Cancer Institute (INCA), and Erasmus Medical Centre in the Netherlands, estimate that strengthening smoke-free legislation between 2000 and 2016 in Brazil averted over 15,000 deaths in children under one year old.
The new research is published today, World Health Organisation World No Tobacco Day, in the journal Tobacco Control.
New research published today in the journal Antiquity reveals that ancient faeces from the prehistoric village of Çatalhöyük have provided the earliest archaeological evidence for intestinal parasite infection in the mainland Near East.
A new report in Science provides the first evidence of a mammal -- the highveld mole-rat -- being immune to pain from exposure to allyl isothiocyanate, or AITC, the active ingredient of wasabi.
The scientists who studied the animals say that understanding how these African rodents evolved to be insensitive to this specific type of pain could point to new directions for solving pain in humans.
CORVALLIS, Ore. - Researchers at Oregon State University have made an important advance in understanding the roles that gut bacteria play in human health.
Learning the mechanisms by which gut microbes affect the health of their hosts opens the door to the development of better, more personalized diagnostic methods and therapies.
Most studies so far have focused on how the composition of the microbiome - i.e., which organisms are present, and in what amounts - associates with health in general or various diseases.
Have you ever spent half an hour trying to take the best photo of your pets but they won't stay still in the perfect angle? This is also true for small animal imaging research using positron emission tomography (PET). Because of this, the use of anesthesia is a widespread practice in animal imaging. It's one of the biggest limitations to imaging studies because anesthesia alters the animal's normal physiological state, blurring the answers to the questions that many researchers have been asking.
AURORA, Colo. (May 30, 2019) - Cannabis use among older adults is growing faster than any other age group but many report barriers to getting medical marijuana, a lack of communication with their doctors and a lingering stigma attached to the drug, according to researchers.
The study, the first to look at how older Americans use cannabis and the outcomes they experience, was published this month in the journal Drugs & Aging.
New research out of Loma Linda University Health suggests that unsupportive parenting styles may have several negative health implications for children, even into their adult years.
People with autism often suffer from gut problems, but nobody has known why. Researchers have now discovered the same gene mutations - found both in the brain and the gut - could be the cause.
The discovery confirms a gut-brain nervous system link in autism, opening a new direction in the search for potential treatments that could ease behavioural issues associated with autism by targeting the gut.
A Florida State University researcher has found gender inequality in U.S. states is bad for everybody's health.
In a new study published in the American Sociological Review, FSU Assistant Professor Patricia Homan developed a new structural sexism approach to the study of gender inequality and health. Her approach goes beyond sexist mistreatment by individuals to examine how the degree of systematic gender inequality in power and resources -- i.e. structural sexism -- in a society can impact people's health.