Culture

Reasonably good evidence suggests that most diets result in similar modest weight loss and improvements in cardiovascular risk factors over a period of six months, compared with a usual diet, finds a study published by The BMJ today.

Weight reduction at the 12 month follow-up diminished, and improvements in cardiovascular risk factors largely disappeared, except in association with the Mediterranean diet, which saw a small but important reduction in 'bad' LDL cholesterol.

HOUSTON -- A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) T-cell therapy. Findings were published in the April 1 online issue of the New England Journal of Medicine.

MINNEAPOLIS - Depression is common in people with Parkinson's disease and contributes to faster physical and mental decline, but it is often overlooked and undertreated. Cognitive-behavioral therapy has shown promising results for treating depression in people with Parkinson's, yet many people don't have access to therapists who understand Parkinson's and can provide this evidence-based depression treatment.

People with Parkinson's disease who engage in cognitive behavioral therapy -- a form of psychotherapy that increases awareness of negative thinking and teaches coping skills -- are more likely to overcome depression and anxiety, according to a Rutgers study.

The study was published in the journal Neurology.

About 50 percent of people diagnosed with Parkinson's disease will experience depression, and up to 40 percent have an anxiety disorder.

Every spring, American robins migrate north from all over the U.S. and Mexico, flying up to 250 miles a day to reach their breeding grounds in Canada and Alaska. There, they spend the short summer in a mad rush to find a mate, build a nest, raise a family, and fatten up before the long haul back south.

In an effort to provide safer working environments for nuclear medicine professionals and their patients, clinics across five continents have shared their approaches to containing the spread of COVID-19 in a series of editorials, published ahead of print in The Journal of Nuclear Medicine. This compilation of strategies, experiences and precautions is intended to support nuclear medicine clinics as they make decisions regarding patient care.

Bethesda, Maryland (April 1, 2020) -- Today, the American Gastroenterological Association (AGA) published new COVID-19 recommendations in Gastroenterology, the official journal of the AGA: AGA Institute Rapid Recommendations for Gastrointestinal Procedures During the COVID-19 Pandemic.

In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit. Found abundantly in our brain cells, tau is normally a team player -- it maintains structure and stability within neurons, and it helps with transport of nutrients from one part of the cell to another.

Neolithic populations have long been credited with bringing about a revolution in farming practices across Europe. However, a new study suggests it was not until the Bronze Age several millennia later that human activity led to significant changes to the continent's landscape.

EVANSTON, Ill. -- The Golden Age of Hollywood is known for its glitz, glamour and classic movies. Northwestern University researchers have peeled back the gilded sheen to reveal an industry tarnished by severe gender inequity.

By analyzing a century of data (1910 to 2010) in the American Film Institute Archive and the Internet Movie Database (IMDb), the researchers found that female representation in the film industry hit an all-time low during the so-called Golden Age. Women representation in the industry still is struggling to recover today.

A new analysis reveals long-term trends in female representation in the U.S. movie industry, including a sharp decline associated with the "Studio System" era that dominated Hollywood from 1922 to 1950. Luís A. Nunes Amaral of Northwestern University, Illinois, and colleagues present these findings in the open-access journal PLOS ONE on April 1, 2020.

CHAMPAIGN, Ill. -- Cells will ramp up gene expression in response to physical forces alone, a new study finds. Gene activation, the first step of protein production, starts less than one millisecond after a cell is stretched - hundreds of times faster than chemical signals can travel, the researchers report.

The scientists tested forces that are biologically relevant - equivalent to those exerted on human cells by breathing, exercising or vocalizing. They report their findings in the journal Science Advances.

HOUSTON -- Although metastatic castration-resistant prostate cancer (mCRPC) typically has limited response to immunotherapy, a subset of patients with pretreatment evidence of active T-cell responses in their tumors experienced prolonged survival after following treatment with ipilimumab in a Phase II trial at The University of Texas MD Anderson Cancer Center.

The results, published today in Science Translational Medicine, suggest that certain patients with mCRPC may benefit from immune checkpoint inhibitors and provide biomarkers for identifying this subgroup.

New artifacts uncovered at the Waim archaeological site in the highlands of New Guinea - including a fragment of the earliest symbolic stone carving in Oceania - illustrate a shift in human behavior between 5050 and 4200 years ago in response to the widespread emergence of agriculture, ushering in a regional Neolithic Era similar to the Neolithic in Eurasia.

Human ancestors that lived more than 3 million years ago had brains that were organized like chimpanzee brains, but had prolonged brain growth like humans, new research from the University of Chicago and other leading institutions shows.

That means these hominins -- the species Australopithecus afarensis, made famous by the Lucy and Dikika child fossils found in Ethiopia -- had a mosaic of ape and human features, a hallmark of evolution.