Culture

What The Study Did: Describes testing for and treatment of children with coronavirus disease 2019 (COVID-19) in Madrid.

Authors: Alfredo Tagarro, Ph.D., M.D., of the Hospital Infanta Sofía de San Sebastián de los Reyes in Madrid, Spain,  is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamapediatrics.2020.1346)

Fungi play an important role for mankind. In the soil, they decompose dead organic material, making it accessible to plants as a nutrient. In industrial biotechnological plants, fungi produce vast quantities of chemicals and food every day. In addition, fungi produce very complex active ingredients that could have potential for medical applications.

To this end, the team identified several thousand proteins, determined their respective amounts in mutant and reference lines and combined the findings with measurements of photosynthetic performance. Their findings were published in the journal Nature Communications on 3 April 2020.

Mutations cause defects

WASHINGTON, April 8, 2020 — Crooner Bing Crosby knew a thing or two about sound. In 1947, recognizing that recorded music sounded better on magnetic reel-to-reel tape than on vinyl records, he invested in a company to develop equipment to record his radio shows. Soon, reel-to-reel tapes and recording and playback machines were a household craze. Now, as reel-to-reel tapes make a comeback among audio buffs, scientists are unraveling the secret of why some decades-old tapes are unplayable, while others retain their original superb audio fidelity.

What The Study Did: The case of a patient with coronavirus disease 2019 (COVID-19) whose main symptom was a loss of smell without nasal obstruction is reported in this article.

Authors: Michael Eliezer, M.D, of Lariboisière University Hospital in Paris, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaoto.2020.0832)

New data from a landmark study done by Monash University researchers in Australia raises significant concerns that even short-term exposure to low level air pollution can affect gene expression, leaving us at risk of other diseases such as cancer, cardiovascular and respiratory diseases.

The rate of pregnant women with opioid use disorder, or OUD, when giving birth more than quadrupled from 1999 to 2014, according to the Centers for Disease Control and Prevention. This indicates a significant public health concern related to adverse health outcomes for both mother and child. Impacts may range from preterm labor or neonatal abstinence syndrome, to adverse child welfare outcomes and early foster care placement.

New research has uncovered the risk factors for Fijians carrying a pneumonia-causing bacteria.

The collaborative study, led by the Murdoch Children's Research Institute (MCRI) and the Fiji Ministry of Health and Medical Services, will help determine further public health interventions to prevent people carrying and transmitting the bacteria.

MCRI's Eleanor Neal said Streptococcus pneumoniae was a leading cause of childhood illness and death around the world.

Research findings suggest gut microbes can effect allergic immune responses. Tasuku Ogita who has recently joined Shinshu University is an expert on teas and their effects on gut bacteria. In this study, his team looked at green tea and the abundance of Flavonifractor plautii (FP) bacteria found in the gut. FP has been reported to be a part of the catechin metabolism in the intestines. Catechin is an antioxidant found in a variety of foods including green tea, of which 30 to 42% of its dry weight is catechin.

Researchers at Lund University in Sweden have succeeded in restoring mobility and sensation of touch in stroke-afflicted rats by reprogramming human skin cells to become nerve cells, which were then transplanted into the rats' brains. The study has now been published in the research journal PNAS.

A European Union (EU) programme aimed at reducing carbon dioxide (CO2) emissions has made significant progress despite low prices in carbon markets, according to a study at the Universities of Strathclyde and Pittsburgh.

Under the EU's Emissions Trading System (ETS), introduced in 2005 in response to the Kyoto Protocol, governments set a cap on an allowable total amount of emissions over a certain period. They also issue tradable emission permits, which allow for one ton of CO2.

The German National Academy of Sciences Leopoldina has published a second ad-hoc-statement entitled "Coronavirus Pandemic - Measures Relevant to Health". The paper focuses on measures, which can contribute to a gradual normalisation of public life. Three measures are particularly important: (1) general use of mouth and nose protection, (2) short-term use of mobile phone data, and (3) increase in testing capacities.

In the summer of 2017, Christie Petrenko, an assistant professor and research associate at the University of Rochester’s Mt.

Using a combination of experimental and computational data, researchers discover paths to optimize pulses from highly intense X-ray beams.

Scientists have long pursued the ability to see the structure of a single, free-form molecule at atomic resolution, what many call the ?“holy grail” of imaging. One potential method involves aiming extremely short, highly intense X-ray free-electron laser (XFEL) pulses at a sample material. But this ultrafast imaging technique also destroys its target, so time is of the essence.

Depression is a common psychiatric disorder and one of the leading causes of disability worldwide. Antidepressants are the first-line treatment for moderate to severe major depressive episodes. Despite their effectiveness, only 40% of patients respond to the first antidepressant they try. A recent paper in Nature Communication strongly suggests that a particular protein, GPR56, is involved in the biology of depression and the effect of antidepressants. The McGill led research team believe that this protein could offer a novel target for new antidepressant drugs.