Culture

WATERLOO, Ontario, April 13, 2020--A new peer-reviewed paper from five prominent ocular scientists will help eye care practitioners (ECPs) instruct and reassure contact lens wearers during the global COVID-19 / coronavirus pandemic.

Unraveling interactions between metal ions and peptides in the body may eventually lead to improved treatments for diabetes, Alzheimer's and other diseases. Understanding these interactions is the focus of research, co-led by KAUST, that is revealing how metals, such as copper, can affect the formation of harmful clumps of misfolded peptide clusters called fibrils, which underpin many diseases.

In a new study, published in the journal Nature, Michigan State University scientists show how plant genes select which microbes get to live inside their leaves in order to stay healthy.

This is the first study to show a causal relationship between plant health and assembly of the microbial community in the phyllosphere -- the total above-ground portions of plants. The work suggests that organisms, from plants to animals, may share a similar strategy to control their microbiomes.

Bethesda, Maryland (April 10, 2020) -- Today, the American Gastroenterological Association (AGA) published new COVID-19 guidance for gastroenterologists treating patients with inflammatory bowel disease (IBD): AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary.

A new X-ray detector prototype is on the brink of revolutionizing medical imaging, with dramatic reduction in radiation exposure and the associated health risks, while also boosting resolution in security scanners and research applications, thanks to a collaboration between Los Alamos National Laboratory and Argonne National Laboratory researchers.

Researchers are interested in genetically modifying trees for a variety of applications, from biofuels to paper production. They also want to steer clear of modifications with unintended consequences. These consequences can arise when intended modifications to one gene results in unexpected changes to other genes. A new model aims to predict these changes, helping to avoid unintended consequences, and hopefully paving the way for more efficient research in the fields of genetic modification and forestry.

VRAC/LRRC8 chloride channels do not only play a decisive role in the transport of cytostatics, amino acids and neurotransmitters. They can also transport the important messenger substance cGAMP from cell to cell and thus strengthen the immune response to infections with DNA viruses. This has now been demonstrated by Prof. Thomas Jentsch, who originally discovered LRRC8/VRAC channels and works at the Leibniz Research Institute for Molecular Pharmacology (FMP) and the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, together with colleagues from Shanghai led by Prof. Hui Xiao.

Harvesting sunlight to make energy is a complex reaction that plants do naturally, but isn't well understood.

A research team led by a Washington State University professor has developed a new tool to study how lipids interact with proteins in plants to help understand how photosynthesis happens.

In the paper, published in the Journal of Biological Chemistry earlier this year, the scientists used this new tool to find the lipid that controls when a photosynthetic protein switches from a light harvester to an energy dissipater in plants.

In a recent study published in the Proceedings of the National Academy of Sciences (PNAS), University of California San Diego researchers moved one step closer to the ability to make heparin in cultured cells. Heparin is a potent anti-coagulant and the most prescribed drug in hospitals, yet cell-culture-based production of heparin is currently not possible.

April 9, 2020 -- The Lancet commentary "Centring sexual and reproductive health and justice in the global COVID-19 response" highlights the detrimental impact of the global COVID-19 pandemic response on sexual and reproductive health and rights (SRHR). The piece emphasizes the threat to SRH services, caused by policies designating these services as non-essential and diverting resources, and calls for vigilance from the SRH community to prevent access to these services from being lost.

Nano-catalysts usually have higher catalytic activity than traditional bulk catalysts. And it is widely acknowledged that the smaller the particle size of the active component is, the higher the activity would be. However, the active component with small size tends to agglomerate or further grow into large particles.

What The Study Did: This case series describes clinical characteristics of patients who died of coronavirus disease 2019 (COVID-19) in China.

Authors: Haibo Qiu, M.D., Ph.D., of Zhongda Hospital, Southeast University in Jiangsu, China, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2020.5619)

What The Article Says: An essay discusses the challenges associated with caring for patients with cancer during the COVID-19 epidemic in Italy.

Authors: Filippo Pietrantonio, M.D., and Marina Chiara Garassino, M.D., of the Fondazione IRCCS Istituto Nazionale dei Tumori in Milan, are the authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaoncol.2020.1426)

What The Study Did: This study investigates the neurologic symptoms of patients with coronavirus disease 2019 (COVID-19) in Wuhan, China.

Authors: Bo Hu, M.D., Ph.D., and Yanan Li, M.D., Ph.D., of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology in Wuhan, China, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaneurol.2020.1127)

What The Viewpoint Says: The article emphasizes the importance of mitigating the mental health consequences of social distancing in the COVID-19 era.

Authors: Sandro Galea, M.D., of the Boston University School of Public Health, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamainternmed.2020.1562)