Culture
NEW YORK, NY--A new global study of 30-day outcomes in children and adolescents with COVID-19 found that while death was uncommon, the illness produced more symptoms and complications than seasonal influenza.
The study, "30-day outcomes of Children and Adolescents with COVID-19: An International Experience," published online in the journal Pediatrics, also found significant variation in treatment of children and adolescents hospitalized with COVID-19.
Anyone who collects mushrooms knows that it is better to keep the poisonous and the non-poisonous ones apart. Not to mention what would happen if someone ate the poisonous ones. In such "classification problems", which require us to distinguish certain objects from one another and to assign the objects we are looking for to certain classes by means of characteristics, computers can already provide useful support to humans.
Carried like stowaways in the guts of international travelers, new and potentially deadly strains of antimicrobial resistant superbugs may be coming to a community near you, suggests new research from Washington University School of Medicine in St. Louis.
In the present study, Dr. Hidetoshi Hayashi (Professor, Nagoya City University) and collaborators screened small-molecule compounds that suppress UPR, using Myanmar wild plant extracts library. The screening system to track X-box binding protein 1 (XBP1) splicing activity revealed that the ethanol extract of the Periploca calophylla stem inhibited the inositol-requiring enzyme 1 (IRE1)-XBP1 pathway. They isolated and identified periplocin as a potent inhibitor of the IRE1-XBP1 axis.
Researchers from the Hubrecht Institute in Utrecht (The Netherlands) and the Max Planck Institute for Molecular Biomedicine in Münster (Germany) used computer simulations to reveal in atomic detail how a short piece of DNA opens while it is tightly wrapped around the proteins that package our genome. These simulations provide unprecedented insights into the mechanisms that regulate gene expression. The results were published in PLOS Computational Biology on the 3rd of June, 2021.
Research Highlights:
Rates of Kawasaki disease - a condition that creates inflammation in blood vessels in the heart and is more common in children of Asian/Pacific Island descent - have substantially decreased in South Korea during the COVID-19 pandemic.
The decrease could be due to mask-wearing, hand-washing, school closures and physical distancing, suggesting Kawasaki disease may be prompted by infectious agents.
The cause of Kawasaki disease is unknown, though it may be an immune response to acute infectious illness.
CAMBRIDGE, MA -- MIT engineers have discovered a new way of generating electricity using tiny carbon particles that can create a current simply by interacting with liquid surrounding them.
The liquid, an organic solvent, draws electrons out of the particles, generating a current that could be used to drive chemical reactions or to power micro- or nanoscale robots, the researchers say.
Many modern fitness trackers and smartwatches feature integrated LEDs. The green light emitted, whether continuous or pulsed, penetrates the skin and can be used to measure the wearer's heart rate during physical activity or while at rest.
Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive.
Published in Nature Communications and part-funded by the NIHR Maudsley Biomedical Research Centre, the research determined a set of age-related cut-off levels of NfL which could inform its potential use in primary care settings through a simple blood test.
The first double-blind experiment analysing the role of human decision-making in climate reconstructions has found that it can lead to substantially different results.
The experiment, designed and run by researchers from the University of Cambridge, had multiple research groups from around the world use the same raw tree-ring data to reconstruct temperature changes over the past 2,000 years.
NEW YORK, June 7, 2021--Recent studies suggest that new brain cells are being formed every day in response to injury, physical exercise, and mental stimulation. Glial cells, and in particular the ones called oligodendrocyte progenitors, are highly responsive to external signals and injuries. They can detect changes in the nervous system and form new myelin, which wraps around nerves and provides metabolic support and accurate transmission of electrical signals.
Just a few bacterial taxa found in ecosystems across the planet are responsible for more than half of carbon cycling in soils. These new findings, made by researchers at Northern Arizona University and published in Nature Communications this week, suggest that despite the diversity of microbial taxa found in wild soils gathered from four different ecosystems, only three to six groups of bacteria common among these ecosystems were responsible for most of the carbon use that occurred.
Consuming large amounts of daily caffeine may increase the risk of glaucoma more than three-fold for those with a genetic predisposition to higher eye pressure according to an international, multi-center study. The research led by the Icahn School of Medicine at Mount Sinai is the first to demonstrate a dietary - genetic interaction in glaucoma. The study results published in the June print issue of Ophthalmology may suggest patients with a strong family history of glaucoma should cut down on caffeine intake.
Terpenoids are omnipresent in almost all living organisms. Prenylated indoles are prominent representatives that usually display potent medicinal properties (e.g. tryprostatin B). Therefore, significant efforts have been devoted to indole prenylation over the past decades. The known protocols often require a multi-step procedure and rely on the use of stoichiometric promoters.
HOUSTON - (June 7, 2021) - If identical versions of 20 people lived out their lives in dozens of different worlds, would the same people be popular in each world?
If you substitute "fruit flies" for "people" in that question, you have a fair description of a Rice University study showing that the evolution of social structures and the positions of individuals within those structures are based partly on genetics.