Culture

What The Viewpoint Says: The considerations and challenges affecting the palliative care specialty and delivery of palliative care in the COVID-19 era, as well as potential solutions, are discussed in this Viewpoint.

Authors: Ambereen K. Mehta, M.D., M.P.H., of the University of California, Los Angeles, in Santa Monica, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamaoncol.2020.1938)

What The Article Says: This essay discusses similarities between a doctor's experiences with diagnoses of cancer and COVID-19.

Author: Urvi A. Shah, M.D., of Memorial Sloan Kettering Cancer Center in New York, is the author.

 To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaoncol.2020.1848)

Repurposing existing medicines focused on known drug targets is likely to offer a more rapid hope of tackling COVID-19 than developing and manufacturing a vaccine, argue an international team of scientists in the British Journal of Pharmacology today.

Tsukuba, Japan - Collective behaviors are the result of dynamic local interactions between individual members of the collective. While the actions of a collective are readily observable, the interactions remain hidden and have traditionally been difficult to analyze. Now, researchers from the University of Tsukuba applied integrated information theory to understand how varying sizes of a collective of fish affect the interactions between its individual members.

Tsukuba, Japan - The germline is the cell lineage of an organism that passes on its genetic material to its progeny. Genetic damage to the germline can cause developmental defects and even death of that same progeny. It is thought that biological mechanisms exist that ensure that aberrant germline cells are eliminated to maintain germline integrity, although the specific molecular basis for this is unknown.

Scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes. This molecular auto-control system of lipidic metabolism, so far unknown, could help prevent the damaging effects derived from an excessive activation of the brown adipose tissue.

According to Carlos García Meca and Andrés Macho Ortiz, researchers at NTC-UPV, this new symmetry allows the conservation of the linear moment between dramatically different physical systems. This paves the way to designing pioneering optical, acoustic and elastic devices, including invisible omnidirectional, polarization-independent materials, ultra-compact frequency shifters, isolators and pulse-shape transformers.

As the COVID-19 pandemic enters its third month, businesses in the United States are marketing unlicensed and unproven stem-cell-based "therapies" and exosome products that claim to prevent or treat the disease. In Cell Stem Cell on May 5, bioethicist Leigh Turner describes how these companies are "seizing the pandemic as an opportunity to profit from hope and desperation."

A new study has found an association between low average levels of vitamin D and high numbers of COVID-19 cases and mortality rates across 20 European countries.

The research, led by Dr Lee Smith of Anglia Ruskin University (ARU) and Mr Petre Cristian Ilie, lead urologist of Queen Elizabeth Hospital King's Lynn NHS Foundation Trust, is published in the journal Aging Clinical and Experimental Research.

Plastic may be an indispensable part of our daily lives, but its robustness and abundance have led to its overuse, putting a huge burden on the environment. Large emissions of plastic waste result in its accumulation in water bodies: in fact, recent studies have estimated about 0.27 million tons of plastic floating in the world's oceans. Because plastic does not decompose in water, it is a serious hazard for the marine life. Thus, to prevent plastic pollution, it is crucial to understand exactly how plastic is emitted into the oceans.

As the world economy is falling into one of the biggest contractions of the last decades, a new study of economic recession patterns finds that the likelihood of a downturn was high even before the onset of the Coronavirus crisis.

Current knowledge about the role of aerosols in the transmission of SARS-CoV-2 warrants urgent attention. Current guidance and public health information has slowly shifted focus towards aerosols as a transmission pathway - predominantly associated with breathing and talking by asymptomatic individuals. Providing guidelines for sufficient inhalation protection will be important in curbing the spread of COVID-19.

Tel Aviv University (TAU) researchers have developed a safe and accurate 3D imaging method to identify sperm cells moving at a high speed.

The research, a study of which was published in Science Advances on April 10, was led by Prof. Natan Shaked of the Department of Biomedical Engineering at TAU's Faculty of Engineering together with TAU doctoral student Gili Dardikman-Yoffe.

Washington - (May 4, 2020) - The first ever set of specific recommendations to support transgender autistic young people was co-created by these youth and their families working hand-in-hand with clinical experts. The resulting model offers clinicians a set of concrete ways to provide this unique population the support they need.

CHAMPAIGN, Ill. -- When tested in brain cells and in a mouse model of Alzheimer's disease, a new compound significantly reduced the number of amyloid plaques in the brain, lessened brain inflammation and diminished other molecular markers of the disease.

The researchers who developed the compound report their findings in the journal ACS Chemical Neuroscience.