Culture
Below please find a summary and link(s) of new coronavirus-related content published today in Annals of Internal Medicine. The summary below is not intended to substitute for the full article as a source of information. A collection of coronavirus-related content is free to the public at http://go.annals.org/coronavirus.
1. ACP: Evidence does not support the use of hydroxychloroquine alone or in combination with azithromycin for prophylaxis or treatment of COVID-19
Scientists are working to find ways to monitor ammonia - an increasing species in the atmosphere closely linked to water eutrophication, soil acidity, and biodiversity loss. But measuring ammonia is not easy because ammonia can change from gas to particles quickly in the air.
Although there are accurate methods to determine ammonia in the lab with the aid of a pump, they are unsuitable for long-term measurements and for large-scale surveys in the field, due to the cost, particularly in terms of manpower, and the need for constant power supply.
Plenty of theories, but nobody knows exactly why we sleep. One thing we know for sure: sleepless nights will not help you make it through the day. There have been many studies exploring how sleep works in the brain and what its purposes are. However, how the synapse - the fundamental building block of the brain contributing to the formation of neuronal circuits - works in relation to sleep has been poorly understood.
n an article published today in Cell Host and Microbe, Professor Subbarao stressed the importance of detecting a neutralising antibody response in recovered COVID-19 patients, and of studies of COVID-19 vaccines in animal models.
Neutralising antibodies prevent infection by binding to a virus and blocking their ability to infect. After an infection, a host can produce neutralising antibodies to protect against future infection.
DALLAS, May 14, 2020 -- People with Type 2 diabetes, but not those with prediabetes, had worse cognitive performance three to six months after a stroke than those with normal fasting blood sugar levels, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.
Research from the University of Sheffield has revealed why some bird species take longer to develop than others
Findings could help scientists predict how animals will adapt to climate breakdown and habitat destruction
The study is the first to consider the importance of lifestyle, environment, evolutionary history and body size when explaining variation
A team of biochemists and virologists at Goethe University and the Frankfurt University Hospital were able to observe how human cells change upon infection with SARS-CoV-2, the virus causing COVID-19 in people. The scientists tested a series of compounds in laboratory models and found some which slowed down or stopped virus reproduction. These results now enable the search for an active substance to be narrowed down to a small number of already approved drugs. (Nature DOI: 10.1038/s41586-020-2332-7).
A new proof-of-concept study published in the May issue of The Journal of Nuclear Medicine has demonstrated that molecular imaging can be used for identifying early response to 177Lu-DOTATATE treatment in neuroendocrine tumor patients.
The optimal minimum legal age for non-medical cannabis use is 19 years of age, according to a study published in BMC Public Health.
A team of researchers at the Memorial University of Newfoundland, Canada, investigated how Canadians who started using cannabis at several young ages differed across important outcomes (educational attainment, cigarette smoking, self-reported general and mental health) in later-life.
Detailed analysis from the epicentre of the Italian COVID-19 outbreak describes increase in cases of rare Kawasaki-like disease in young children, adding to reports of similar cases from New York, USA and South East England, UK. Syndrome is rare and experts stress that children remain minimally affected by SARS-CoV-2 infection overall.
Harvard University scientists have identified a new gut-brain connection in the neurodegenerative disease amyotrophic lateral sclerosis, or ALS. The researchers found that in mice with a common ALS genetic mutation, changing the gut microbiome using antibiotics or fecal transplants could prevent or improve disease symptoms.
Published in the journal Nature, the findings provide a potential explanation for why only some individuals carrying the mutation develop ALS. They also point to a possible therapeutic approach based on the microbiome.
Whilst the whole world is in lockdown during the current Corona crisis, certain cells within our bodies are still travelling long-distance: while this happens when you develop pneumonia, any ordinary cut on your finger will also trigger white blood cells--aka leukocytes--to instantly move out of your blood vessels into the site of inflammation. Similarly, cancer cells, which can originate in any tissue or organ, can also spread and reproduce far away from their place of origin. The result: a metastasis.
Researchers at Karolinska Institutet in Sweden have compared two ways of delivering cognitive behavioral therapy, CBT, to treat people with health anxiety, a condition that may increase in the wake of COVID-19. Out of about 200 study participants, half received CBT over the Internet and half were treated with conventional face-to-face CBT. The results, published in JAMA Psychiatry, show that Internet-delivered treatment had comparable effects, and could serve as an alternative to physical meetings in helping people who are worried about their health.
What The Study Did: This study combined the results of 57 studies with 7,000 participants to examine how effective are interventions and programs to enhance the social, emotional and spiritual aspects of wisdom.
Authors: Dilip V. Jeste, M.D., of the University of California, San Diego in La Jolla, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamapsychiatry.2020.0821)
A study led by researchers at the Babraham Institute in collaboration with the Wellcome Sanger Institute has uncovered how variations in a non-protein coding 'dark matter' region of the genome could make patients susceptible to complex autoimmune and allergic diseases such as inflammatory bowel disease. The study in mice and human cells reveals a key genetic switch that helps immune responses remain in check.